In these studies, we developed a method to simultaneously record the activity of multiple excitatory
thalamic neurons (ETN) together with the axonal activity of inhibitory
thalamic neurons (ITN) in the same brain volume.
Recording from downstream neurons in the caudate and from
thalamic neurons projecting to the medial frontal cortex indicated that this phenomenon originates within cortical networks.
Seibt J., Schuurmans C., Gradwhol G., Dehay C., Vanderhaeghen P., Guillemot, F. and Polleux F. (2003) Neurogenin2 specifies the connectivity of
thalamic neurons by controlling axon responsiveness to intermediate target cues.
Dr. Lee's team flashed laser pulses onto light sensitive central
thalamic neurons of sleeping rats, which caused the cells to fire.
Previous studies suggested that stimulation of
thalamic neurons may awaken patients who have suffered a traumatic brain injury from minimally conscious states.
Not exact matches
These channels enable
thalamic reticular nucleus
neurons to generate burst firing, leading the
neurons to enter a hyper - excited state.
The work of Kremkow and colleagues indicates that the organization of all maps originates from the same principle: an arrangement of
thalamic afferents that minimizes differences in spatial position, eye input and light / dark polarity among neighboring cortical
neurons.
«Our latest research findings support a newly emerging model of how the brain focuses attention on a particular task, using
neurons in the
thalamic reticular nucleus as a switchboard to control the amount of information the brain receives, limiting and filtering out sensory information that we don't want to pay attention to,» says senior study investigator and neuroscientist Michael Halassa, MD, PhD.
The distribution and morphology of
neurons and axonal endings (puncta) immunostained with antibodies to gamma - aminobutyric acid (GABA) and glycine (Gly) were analyzed in auditory brainstem,
thalamic,
YanGang Sun, Juan Pita - Almenar, Chia - Shan Wu, John J Renger, Victor N. Uebele, Hui - Chen Lu, Michael Beierlein (2013) «Biphasic cholinergic synaptic transmission controls action potential activity in
thalamic reticular nucleus
neurons», Journal of Neuroscience 33: 2048 - 59.
Significance of the
Thalamic Reticular Nucleus GABAergic
Neurons in Normal and Pathological Activity of the Brain