Sentences with phrase «thalidomide binds»
Handa's team found that beads tagged with thalidomide bound to a little - known protein called cereblon, which is expressed widely in both embryonic and adult tissues.
http://www.sciencemag.org/ Not exact matches
In both zebrafish and chick embryos, adding a version of cereblon that doesn't bind to thalidomide seemed to blunt the drug's effects.
Now, for the first time, researchers have found a specific protein that binds to thalidomide and may help explain its devastating effects on fetal development.