Sentences with phrase «thalidomide birth»

FDA medical officer Frances Oldham Kelsey averted the tragedy of thalidomide birth defects in the United States

Holmes also notes that the relative paucity of thalidomide births in the United States means that few researchers there can speak with authority on the drug's effects.

Not exact matches

Meanwhile, reports of startling birth defects in babies born to mothers who had taken thalidomide were surfacing in Germany, Australia and other countries where the drug was legal — including Kelsey's native Canada.

For example, in its current work, the team showed that the micro-hearts didn't develop properly if exposed to thalidomide, a drug that infamously resulted in birth defects when pregnant women took it to treat morning sickness.

If you look at the original work on the epidemiology of thalidomide [a morning - sickness drug that turned out to cause birth defects], there were specific time points where, if the woman was exposed, the baby had a high probability of having bona fide autism.

One victory: Gilla Kaplan, now a researcher at the Public Health Institute in Newark, New Jersey, found that the drug thalidomide — banned in 1962 after it was linked to severe birth defects — could reduce inflammatory responses and might be valuable in managing HIV, tuberculosis, cancer, and autoimmune diseases such as lupus.

The prime example is thalidomide, which was outlawed in the 1960s because it caused birth defects but has now found a niche in the treatment of cancer and leprosy.

To test the potential of the system as a drug - screening tool, the researchers exposed the differentiating cells to thalidomide, a drug known to cause severe birth defects.

When scientists tried to clarify the fatal effects the drug had when taken by pregnant women, they found that only (S)- thalidomide caused birth defects, whereas (R)- thalidomide had the desired calming and anti-nausea effects.

In other work, Henning Moelle has been acting as international lead counsel for the pharmaceutical company Grünenthal in product liability claims for alleged birth defects caused by thalidomide.