Not exact matches
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and
other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger
than anticipated shift in payer mix to more highly discounted payer segments and geographic
regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or
other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or
at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over
other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or
other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and
other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
On some measures, and in some products, Australian markets are smaller
than others in the Asian
region, but nonetheless,
at the height of the Asian and Russian crises, overseas banks chose to operate in Australia to cover positions established in Asian markets because liquidity in those markets was inadequate
at the time.
Souza Cescon Barrieu & Flesch Advogados represented clients in 32 deals valued
at $ 2.3 billion last year — a higher value
than any
other law firm in the
region, according to Dealogic.
Spreads in Asia, which were already
at significantly lower levels
than in
other regions, have been relatively steady in recent months.
According to a Reuters article, «the total stock of non-performing loans (NPL) in the EU is estimated
at over $ 1 trillion, or 5.4 % of total loans, a ratio three times higher
than in
other major
regions of the world.»
In the brutal politics of a
region where the withdrawal of American power has led to seven demons worse
than the first, Chaldean Catholics are especially
at risk because, as Father Bazi put it, they «can't play the game the way the
others do» — they can't indulge in revenge killings because their faith forbids them to do so.
Owing to this, the UHT milk market is rising in the Asia Pacific
region at a faster rate
than in
other regions.
Today, Latin America is more urbanized
than any
other part of the world — 85 percent of its population will live in cities by 2025 — placing the
region at the forefront of the fight to reduce food waste in the urban environment.
The Welsh unemployment rate is reducing
at a slower rate
than any
other UK
region, new figures released today show.
During a news conference
at Glens Falls Hospital Wednesday, Governor Andrew Cuomo said that the environment is one of the factors they'll look
at, as they study why Warren County and three
other regions of the state have higher cancer rates
than the rest.
Addressing members of the Tertiary Education Institution Network, TEIN,
at the Tamale Technical University, Vice President Amissah - Arthur said it is a known fact that some
regions are well resourced
than others and it is incumbent on government to bridge that gap as part of nation building.
For more
than two hours hours, Capital
Region Democratic Rep. Paul Tonko took questions
at a town hall meeting on, among
other topics, environmental policies pushed by Trump, the manufacturing workforce, efforts to repeal of the Affordable Care Act and hate crimes that have gained considerable attention since the election.
The unemployment rate also compares favorably with those in most
other upstate cities, with only Glens Falls,
at 5.3 percent, and Ithaca,
at 4.8 percent, posting lower rates
than the Capital
Region.
Mayo's resolution sat in committee for more
than a year before it came to the legislature for a vote, where it was defeated shortly after the Times Union revealed through a two - month - long examination of municipal payrolls and
other public records that
at least 11 local elected officials in the Capital
Region have
at least three relatives each working in local government.
Brain scans show that
at times some areas are more active
than others, but no
region in a healthy brain is simply turned off.
In the deep forest, the chimps are fearless, «approaching us in the trees to get a better look,» Hicks says, rather
than fleeing
at the sight of humans, as chimps in
other regions tend to do.
No less
than four
other expeditions were in the Antarctic
regions at the time while Amundsen was forcing his way south.
More
than two weeks after Hurricane Sandy, now that its floodwaters have receded and the
region's utilities and transportation systems have largely been restored, researchers and authorities are beginning to look
at Sandy's
other effects.
In the late 1990s brain - imaging studies revealed that discrete
regions of the temporal lobe — a section of the human brain important for object recognition — fired up more strongly when people looked
at faces
than at any
other thing.
But immigrants from Latin America are less likely to have those requests granted
than are immigrants from
other regions, according to a new study conducted by scholars
at MIT and Brown University — a study that also suggests a potential remedy for this problem, by finding that this regional disparity does not exist when officials examine cases in greater detail.
Mud cores show that sea level rise is happening in the
region faster
than at any
other time over the past 1,500 years.
«We tend to measure the impact of human activity based on the area it affects on a map, but mountaintop mining is penetrating much more deeply into the earth
than other land use in the
region like forestry, agriculture or urbanization,» said Emily Bernhardt, a professor of biology
at Duke and co-author on the study.
Its replacement is not due to come online until 2017, leaving a huge data gap
at a time when the Arctic is warming faster
than any
other region and its ozone hole is approaching the size of the Antarctic's.
But some
regions may become redder and darker
than others because parts of the atmosphere collapse, exposing those spots to more surface - darkening radiation from space, researchers report March 22
at the Lunar and Planetary Science Conference in The Woodlands, Texas.
In a study of structural brain connectivity led by the University of Illinois
at Chicago and UCLA, those participants with anorexia nervosa who scored lowest on a test measuring their ability to form insight had more connective abnormalities
than other patients in brain
regions linked to error detection and conflict monitoring as well as self - reflection.
Doctors
at the Abramson Cancer Center treat more cancers
than those
at many
other cancer centers, and are available to see patients
at multiple locations throughout the
region.
No
region in China eats
at these macronutrient ratios, but one comes substantially closer
than others: the county of Tuoli.
My guess is that it may seem like your lower ab muscles are «hard to develop,» but it's not really an issue of «muscle development»
at all, you simply have too much body fat and are storing it in your lower abdominal
region more readily
than other parts of your body and you can't see the muscles through the fat.
By Our Friends
at Food Revolution Why do people in some
regions live longer — and healthier —
than others?
Do couples, who happen to be neighbours with the Angel of the North, spend more time yelling
at each
other than any
other region?
«If you look
at the starting point of many pupils in the North East, the
region is making much better progress
than other areas.»
The lower bound interest rates for
Regions Bank unsecured personal loans are generally higher
than those
at other institutions — some lenders, such as SoFi and LightStream, have starting rates under 6 %.
In fact, there are
at least 35 DOP and IGP products in Emilia Romagna, more
than any
other region in Italy, and I think the world.
Protected from Pacific breezes by surrounding hillside, this
region is warmer
than other areas of Sonoma, yet cools a bit
at night.
Tides and beach breaks
at the Playa Carmen are less challenging
than in
other surf spots on the Pacific
region of Costa Rica, which makes it suitable for surfing beginners.
- the team has been adding weapons one by one because they want the same amount of attention for each weapon - the team learned that when they added two new weapons
at once, one would end up getting overshadowed by the
other - there were more new stages
than returning stages because bringing back old stages would have little surprise - since they want to satisfy both new and returning players, they changed the order of stage additions - there weren't any major direction changes in balancing from Splatoon 1 - there have been more pattern combinations between weapons and stages, so there was more involved to balance them all - matchmaking is handled by getting 8 players with similar rank points, and then they're split by weapons - the rank point gap between S + players is bigger
than ordinary players - only about one in 1,000 active players are in the S +40 to S +50
region in Ranked Battles - there's even less
than one in 10 players that reach S +, while 80 % of the overall player base are in A or less - about 90 % of S + ranked players are within a + / -150 hidden ranked power range - rock was the popular genre in Splatoon, so they tried changing it for the sequel - they prioritized making good background music first before forming the band to play that music - the design team would make the CD jacket - like artwork afterwards - due to this, the band members would often change; some getting added while some
others removed - Off the Hook is an exception, as they first decided they would be a DJ and rapper along with their visuals first - Off the Hook's song came afterwards - In Splatoon street fashion was the trend, but in Splatoon 2 they tried adding more uniqueness - the aim was to add Flow with ethnic clothing and Jelfonzo with high fashion - all Jellyfish in this world are born by splitting, which means Jelfonzo was born by splitting from Jelonzo - Jellyfish are like a hive mind - when they hold a wedding ceremony, they're just simply holding the ceremony - Jelonzo and Jelfonzo start gaining their own consciences so they can speak - Flow used her working holiday to go on a trip before reaching Inkopolis Square - during the trip, she met the owner of Headspace - the owner liked her, so she got hired to work there - Bisk has a unique way of speaking: anastrophe - the team tried to express him as an adult man - they made him into a giant spider crab because they wanted someone with high posture - he came from a cold country and broke up with his girlfriend to join a band - just like Flow, he became attracted to squids - Crusty Sean finally has his own shop, but he opened it because he's someone who follows the current trends - one of the trends happens to be people opening their own shops - drink tickets aren't stacked, but the probability is higher
than a single brand - the music in Inkopolis Square changes depending on the player's location - sounds contribute to creating atmosphere in the location - the song
at front of Grizzco Industries had an atmosphere that feels like some smell can radiate from the game screen - as for Salmon Run, they imagined it as a Japanese restaurant outside Japan that is not run by a Japanese person - each time the player moves between the shops, the game uses an arrange shift that shows the personality of each inhabitant - the arrangement in Shella Fresh is related to Bisk's guitar and mystery files that describe his past - with the Squid Sisters moved to Hero Mode, Off the Hook was put in charge in guiding battles and festivals - Bomb Rush Blush has an orchestra «because it would sound like the final boss» - the team wanted to express the feel of the story's real culprit with this music - the probability of each event occurring in Salmon Run is different - there are no specific requirements, meaning they're picked randomly - this means it's possible for fog to appear three times in a row - the Salmon have different appearances based on the environment they're raised in - if the environment is harsher, they would become large salmon - Steelheads and Maws have big bodies, while Scrappers and Steel Eels have high intelligence - Salmons basically wield kitchenware, but everybody else has a virtue in fighting to actually cook the Salmons - Grill is the ultimate form of this - when Salmons are fighting to the death, they can feel the same sense of unity - they would be one with the world if they were eaten by
other creatures, and they also fight for the pride of their race - MakoMart is based on a large supermarket in America - the update also took place on Black Friday in America, which was why Squids are buying a lot of things in the trailer - Arowana Mall looks like it has more passages because there are changes in tenants and also renovation work - Walleye Warehouse has no changes
at all, because the team wanted to have
at least one map that stayed intact - the only thing different in this map is the graffiti, which is based on the winner of Famitsu's Squid Fashion Contest - all members in the band Ink Theory graduated from music university - they are well - educated girls who also do aggressive things - the band members wearing neckties are respecting the Hightide Era from the prequel - the team will continue adding weapons and stages for a year, and Splatfests for two years - the team will also continue to make more updates including balancing
At different moments, diverse aesthetic interests have flourished so that Britain, despite having fewer cultural, economic and political ties with the
region than with
other parts of the globe, throughout the past century has nevertheless been engaged with and touched by key aspects of Latin American art.
If the money is being divided up among a number of states /
regions, very little will get done
other than some studies and minor upgrades to existing systems, which is certainly a start, but not really the funding levels and speed
at which we should be doing this.
The warm air above nocturnal or polar inversions, or even stable air masses with small positive lapse rates, are warmer
than otherwise because of heat capacity and radiant + convective heating during daytime and / or because of heating occurring
at other latitudes /
regions that is transported to higher latitudes /
regions.
These new «secondary» forests are emerging in Latin America, Asia and
other tropical
regions at such a fast pace that the trend has set off a serious debate about whether saving primeval rain forest — an iconic environmental cause — may be less urgent
than once thought.
One example is a plan to look
at the upper portions of Smith Glacier in West Antarctica, which is thinning faster
than any
other glaciers in the
region.
Here we are moving out of the «very likely» (> 90 %)
region into a more uncertain category: let's be generous and call it «more likely
than not» (> 50 %) that this would occur
at all, all
other things being equal.
But, they say, their work does imply that factors
other than ocean temperature,
at least for thousands of years, appear to have played a pivotal role in shaping storminess in the
region.
If China can do it, the hope,
at least, is that
other rapidly growing
regions will also modernize more cleanly
than the West did.
Although the energy consumption of developing countries in
other regions is expected to grow
at a slower pace
than in Asia, rates are still expected to exceed the global average (Table 1).
With more
than half the world's population, Asia has more
at stake
than any
other region.
From that he asserts that the Arctic
at that time — and all
other previous times — had «one
region warmer
than normal while another
region was cooler».
The results here reveal a larger picture — that the western tropical Indian Ocean has been warming for more
than a century,
at a rate faster
than any
other region of the tropical oceans, and turns out to be the largest contributor to the overall trend in the global mean sea surface temperature (SST)»
According to several news reports (for example, by the Times Picayune, Sept. 9), the Associated Press collected raw data from state regulatory agencies and
other sources and performed an analysis which revealed that more
than 30 fuel and chemical storage tanks
at facilities in the
region collapsed or otherwise failed during Hurricane Harvey, releasing more
than 600,000 gallons of crude oil, gasoline, and
other fuels and chemicals.
What we — and
other competent researchers — have all found is that the warmth was far more regional
than modern warmth, with some large
regions, like the tropical Pacific, having been unusually * cold *
at the time, and when you average over the globe, the warmth of the medieval warm period / medieval climate anomaly simply doesn't reach modern warmth.