Sentences with phrase «than cell lines»

When it comes to the deadly skin cancer melanoma, studying functional tissue rather than cell lines may better provide insight into the disease's development, according to new research from a Howard...

Not exact matches

Due to the 2.5 GW exemption for imported cells, there is no more reason to install cell lines in the U.S. than there was before the Section 201 process.

Modern psychosomatic medicine has made some progress in analyzing along these lines; for example, it seems quite possible that the emotional tone of my soul may directly alter the patterns of physical feeling in my stomach.4 Still, we should not suppose too quickly that the aims of a human personality have any very effective direct influence on the molecules of body cells, other than those in the brain.

In my district, someone in my food services department described how kids who couldn't partake in a la carte were getting their photos taken by cell phone in the «uncool» subsidized meal line to shame them, and some of these kids would rather go hungry than be seen standing in that line.

Despite the presumed virulence of the strain — experiments with mouse lungs showed it produces 1000 times more bacteria in infected cells than do standard varieties — Valway says the number of TB cases that developed were kept in line with other typical outbreaks, which «shows that doing good contact investigations is important and preventative therapy works.»

In these instances, the committee says, the use of existing embryonic cell lines derived from embryos fewer than 14 days old should be considered before resorting to the use of cells taken from surplus in vitro fertilization embryos fewer than 14 days old.

Where permitted, ES cells should be drawn from sources in the following order: (1) existing ES cell lines, originating from ES cells derived from embryos less than 14 days old; and (2) surplus human embryos less than 14 days old that were created for fertility treatment.

Under the Obama administration, the number of embryonic stem cell lines available for federally funded research had more than tripled, but no money was going toward the creation of any cell lines (a process that destroys the embryo).

The researchers also tested a Runx2 knock - down variant of a human multiple myeloma cell line and found that it produced significantly less tumor growth in immunodeficient mice than the original human multiple myeloma cells.

In this study, rather than studying one iPS cell line, the researchers derived and sequenced 10 iPS cell clones from each patient tissue sample to get a better understanding of mitochondrial DNA mutation rates.

When they sequenced the iPS cell lines, they found higher numbers of mitochondrial DNA mutations, particularly in cells from patients older than 60.

In its comment on the draft policy, the the International Society for Stem Cell Research asks NIH to define some «core principles» covering what is ethically acceptable rather than set explicit rules that might exclude «lines that have been in routine use for the past ten years.»

But cell towers are easier to install than telephone land lines, even in such challenged areas, and mobile or cellular phones are widely used among the poor and wealthy alike.

One cell line produced ten times more than any of the others, most produced very few, and some produced none at all.

Proponents of ESC research counter that most of the new cell lines could be derived from donated, unused human embryos created by couples seeking fertility treatment, and that more than a third of zygotes fail to implant after conception, so those would be lost by chance anyway.

The researchers showed that cabazitaxel worked better than docetaxel in human prostate cancer cells lines that were resistant hormone treatment, both in terms of slowing cancer - cell growth and in its ability to kill cancer cells.

In women younger than 18, the layer of cells lining the cervix and genital tract is thinner than in mature women.

If a woman has an abortion, she's left with a large number of these immature cells lining her breast ducts, and she is therefore more vulnerable to cancer down the road — 30 percent more vulnerable, Brind says, than a woman who has never had an abortion.

Significantly, most of the tissues come directly from patient samples rather than from cell lines that have been developed for lab use.

People travelling on the Jubilee line — which opened in 1979 and was extended in 1999 — breathe in fractionally more fungal cells than those on the Central line, which opened in 1900.

The toxicity of chokeberry extract on normal blood vessel lining cells was tested and found to have no effects up to the highest levels used (50 ug / ml), suggesting that the cell death effect is happening in a way other than through preventing new blood vessel formation (anti-angiogenesis), a process that is important in cancer cell growth.

We found that the U87MG cell line from ATCC had a different DNA profile than the original cell line in Uppsala», says Bengt Westermark.

Microscopic imaging of the intestines revealed that the average distance between gut bacteria and the intestinal cells was reduced by more than half; bacteria seemed to be advancing toward the gut lining.

«Further tests conducted at the Institute for Molecular Bioscience demonstrated that this compound was more toxic to cancer cell lines than other compounds found in sea slugs.»

One is a relatively unknown company, CyThera, set up less than 2 years ago in San Diego, that claims to have nine embryonic stem cell lines and is currently trying to develop pancreatic islet cells for treatment of diabetes.

All Dicty lines, especially in the winning group, also got a boost from their quick starts, moving from maze's starting area into the channels much faster than the HL60 cells.

However, more than 90 percent of the cell lines had a strong dependency on at least one of a set of 76 genes, suggesting that many cancers rely on a relatively few genes and pathways.

As a result, in late June, more than a year after Science retracted the 2004 paper, researchers at ISC were able to claim the discovery of human parthenogenetic cell lines as their own in the journal Cloning and Stem Cells.

One of the gene areas identified suggests that cells within the lining of the uterus play a larger - than - expected role in the length of pregnancy, which in turn provides a new target for medications to help prevent preterm birth.

Although the president's decision may temporarily halt a political push for more research opportunities, his assertion that some 60 ES cell lines would be available for research is more than twice the number most scientists would cite.

«Such a cell line could produce say 10 times, 100 times, 1000 times more of those interesting compounds than the plant out there,» says Reuter.

A bill that would allow federal funding for derivation of new lines of human embryonic stem (ES) cells passed the U.S. House of Representatives yesterday 238 to 194 after more than four hours of debate.

This study utilized 36 well - characterized melanoma cell lines assembled by the MGH Center for Molecular Therapeutics to test all possible combinations of more than 100 oncology drugs, two - thirds of which are currently in clinical use.

More than 5,775 potential drug combinations, as well as each single drug, were screened against each cell line, looking for effects on the number and viability of tumor cells.

In this report, we found that CSCs (CD24 − / CD44 + / ESA +) isolated from metastatic breast cell lines are significantly more metastatic than non-CSC populations in an organ - specific manner.

«By using an animal model to expand tumor cells recently removed from patients, we hoped to re-create more closely what actually happens in patients with pancreatic cancer rather than by using existing artificial cell lines,» said Wei Zhang, Ph.D., an endowed Hanes and Willis Family Professor in cancer at Wake Forest School of Medicine, a part of Wake Forest Baptist, and principal investigator of the study.

We have generated more than 10 knockout cell lines using homologous recombination and AAV - based system.

In the last decade, PHENOMIN has generated and validated more than 30 cell specific inducible CreERT2 deleter lines (http://www.ics-mci.fr/mousecre).

In studies of cell lines from more than 20 Friedreich's patients, the molecular prosthesis restored expression of the frataxin protein.

While none of the cells managed to efficiently break down imidacloprid, one cell line, containing a P450 gene called CYP9Q3, metabolized almost all of its thiacloprid dose in less than 60 minutes, Nauen says.

The exception was one cell line, out of 5, where the mitochondrial DNA type associated with the transferred pronuclei increased over time to much higher levels than present in the embryo after PNT.

To better understand this complex tissues and its functions — and the diseases that affect it — a multicenter team led by researchers at the Broad Institute of MIT and Harvard and Massachusetts General Hospital has released a census of the cells that make up the lining of the small intestine, using gene expression profiles of more than 53,000 individual cells from the mouse gut or gut organoid models.

«Finally, to assess the potential fate of mtDNA under condition when the cells can replicate extensively (longer than allowed by UK law), they derived human embryonic stem cell (hESC) lines from five ePNT blastocysts.

It also works in cells taken directly from human patients, which are usually much more difficult to manipulate than human cell lines grown specifically for lab research.

The majority of gene - targeting experiments in mice are performed in 129Sv - derived embryonic stem (ES) cell lines, which are generally considered to be more reliable at colonizing the germ line than ES cells derived from other strains.

Still, laying siege to cancer cells» supply lines may cast a wider net than targeted therapies aimed at rare oncogenic mutations.

More than 50,000 cell lines derived from patients are cryopreserved, representing an invaluable patrimony for the study of over 500 pathologies.

Shaheen, whose granddaughter was recently diagnosed with Type 1 diabetes, and Fox have joined a majority of medical researchers around the country who believe that embryonic stem cell research offers more potential than other stem cell lines, which have also attracted research attention.

Tissue / Cell line enriched (expression in one tissue at least five-fold higher than all other tissues / cell liCell line enriched (expression in one tissue at least five-fold higher than all other tissues / cell licell lines)

On the other hand, cells of line 4.1 differentiated into endoderm lineages more easily than cells of line 11.1 (data not shown).