The new study by NYU Langone Medical Center researchers reveals that mice given lifelong low doses of penicillin starting in the last week of pregnancy or during nursing were more susceptible to obesity and metabolic abnormalities
than mice exposed to the antibiotic later in life.
The same researchers found that mice exposed to chemicals released by disposable diapers were more likely to have irritated airways
than mice exposed to emissions from cloth diapers.
Not exact matches
Twelve transgenic piglets endowed with a
mouse UCP1 gene were better able to maintain their body temperature
than their unmodified counterparts when they were
exposed to cold for a 4 - hour period, the authors report today in the Proceedings of the National Academy of Sciences.
Both kinds of vaginal bacteria were eliminated from the bladder within 12 hours, but this short sojourn in the bladder was enough for E. coli to reappear in the urine of more
than half of the
mice exposed to G. vaginalis, indicating a recurrent UTI.
The scientists
exposed a group of
mouse lemurs to moderate chronic caloric restriction (30 % fewer calories
than their peers consuming a normal diet) from the outset of early adulthood (Restrikal cohort, see visuals below).
The researchers found that wounds
exposed to vibration five times a week for 30 minutes healed more quickly
than wounds in
mice of a control group.
As rodents prefer to spend more time with novel objects
than familiar ones, the researchers first
exposed the
mice to two identical objects (cones or pyramids, in either black or white).
As rodents prefer to spend more time with novel objects
than familiar ones, the researchers first
exposed the
mice to two identical objects for habituation (cones or pyramids) and later measured the animals attention towards a novel object with different shape.
The analysis found the
mice that were
exposed to BPA had a significant decrease in beta cell mass and lower levels of insulin secretion
than the control animals.
Offspring also had more neurons that detect the orange blossom scent
than mice whose parents weren't
exposed to the scent.
«Most surprisingly, the male
mice born to male
mice that were
exposed to DEHP also exhibited similar reproductive abnormalities — indicating prenatal exposure to DEHP can affect the fertility and reproductive capacity of more
than one generation of offspring,» Barakat said.
Some studies have found an increased cancer risk in
mice and rats who were fed acrylamide, but those studies used doses between 1,000 and 10,000 times higher
than levels that people would be
exposed to in food.
They report that females
exposed to the higher dose of BPS during pregnancy and lactation spent significantly more time on the nest
than controls at one observation point, an unexpected finding given that
mouse mothers usually spend less time on the nest as pups grow and develop.
When they were treated with leptin over the course of two days, control animals that weren't
exposed to either chemical lost more weight
than BPA - or DES -
exposed mice.
When they
exposed these
mice to the cold, the animals developed far fewer beige fat cells
than did normal animals, suggesting that macrophages were key to browning of white fat.
Mice that were
exposed to the two compounds had larger and denser breast cancer tumors
than the control group.
Their tumors were also larger and more frequent
than in
mice not
exposed to triclosan.
In another study, his team found that
mice given chow containing trace amounts of arsenic, then
exposed to a standard daily dose of ultraviolet light, had higher rates of skin cancers
than mice given untainted chow.
When they
exposed the treated
mice to the influenza virus, the animals recovered from the illness even better
than healthy
mice infected with flu that had not undergone the treatment.
Mice that were previously
exposed to early - life stress performed worse
than control animals and demonstrated poor learning and memory skills.
That research showed that
mice on a normal diet who were
exposed to low doses of antibiotics throughout life, similar to what occurs in commercial livestock, packed on 10 to 15 percent more fat
than untreated
mice and had a markedly altered metabolism in their liver.
To the researchers» surprise, the
mice subjected to both prenatal infection and stress during puberty showed far greater behavioral deficits and cellular changes in brain regions relevant to schizophrenia
than those that had been
exposed to infection or stress alone.
Mice living in cages with these fabrics for up to six months had more cell damage in their liver and brain than mice who weren't exposed to this third - hand sm
Mice living in cages with these fabrics for up to six months had more cell damage in their liver and brain
than mice who weren't exposed to this third - hand sm
mice who weren't
exposed to this third - hand smoke.
When researchers in Paul Kellam's group at the Wellcome Trust Sanger Institute
exposed mice treated with Amphotericin - B to influenza A virus, the animals became very ill and lost more
than 25 percent of their body weight.
Mice given this bacterial strain and then exposed to enough UV light to cause skin tumours developed around 20 per cent fewer tumours than mice given a different strain (Science Advances, doi.org/gcz8
Mice given this bacterial strain and then
exposed to enough UV light to cause skin tumours developed around 20 per cent fewer tumours
than mice given a different strain (Science Advances, doi.org/gcz8
mice given a different strain (Science Advances, doi.org/gcz86k).
In another experiment,
mice lacking the cells that produce serotonin scratched less
than normal
mice when
exposed to a skin irritant.
«Female
mice exposed to BPA and EE were less active
than the control
mice,» Rosenfeld said.
Mice given this bacterial strain and then exposed to enough UV light to cause skin tumours developed around 20 per cent fewer tumours than mice given a different strain (Science Advance
Mice given this bacterial strain and then
exposed to enough UV light to cause skin tumours developed around 20 per cent fewer tumours
than mice given a different strain (Science Advance
mice given a different strain (Science Advances...
In other preliminary experiments, Martins - Green and her team found that
mice exposed to THS are less social
than unexposed
mice.
When blood from vaccinated subjects was then transferred to
mice, more
than 90 percent of the animals were protected from death and illness despite being
exposed to a lethal dose of the Zika virus.
The researchers observed two versions of the experiment for less
than 20 minutes:
mice with injected hearts
exposed to light and
mice that were kept in the dark.
Mice that had been
exposed to a pollutant now moved more quickly around the stranger
than unexposed animals did.
The study found that when
mice with Staphylococcus epidermidi (and therefore, 6 - HAP as well) were
exposed to cancer - causing UV rays, they developed significantly fewer tumors
than the
mice without the 6 - HAP - producing bacteria.
A new study suggests that
mice who were prenatally
exposed to phthalates — a chemical commonly found in beauty products — were less likely
than others to exercise as adults.
In a study involving dietary ketosis via a low carbohydrate diet (less
than 10 percent of total calories), compared to subjects on a 50 percent carbohydrate diet, the low - carbohydrate subjects demonstrated better performance on memory tests, with higher scores being correlated to higher serum KB levels.14 A study using cultured
mouse hippocampal cells showed that addition of the KB β - hydroxybutyrate (β - OHB) to cells
exposed to Aβ resulted in no decrease in the numbers of dendrites or total neurons — two of the noted pathological changes in AD.
The
mice developed far fewer tumors
than a control group, and when
exposed to additional carcinogens demonstrated a significantly lower risk of developing cancers of the stomach, colon and liver.
In studies using estrogen - resistant
mice, exposure to Tordon caused significant hormonal effects — reproductive problems and bone malformations.1, 2 Where I live in the Bitterroot Valley of Montana, more people and animals are
exposed to Tordon each spring
than to any of the many other pesticides used.
Although all groups of db / db
mice weighed significantly more
than WT
mice [Fig. 1 (a — d); effect of genotype, F1, 36 = 76.55, P < 0.001], db / db
mice exposed to TE weighed significantly less
than SED db / db
mice at the end of the experiment [Fig. 1 (d); post hoc comparison, db / db SED vs db / db WBV, not significant; db / db SED vs db / db TE, t14 = 3.75, P < 0.01].