Sentences with phrase «than mice treated»

The scientists of the Farncombe Family Digestive Health Research Institute at McMaster University discovered that mice that harboured in their gut the opportunistic bacteria Pseudomonas aeruginosa (Psa) isolated from celiac patients, metabolized gluten differently than mice treated with Lactobacillus, often used as probiotics.

The researchers showed that female mice swabbed with HSV - 2 and an ointment containing ZOTEN had significantly fewer genital lesions than mice treated with a cream lacking ZOTEN.

Not exact matches

Both TRPV1 / WT and KO mice treated with capsaicin and TPA together exhibited higher COX - 2 protein levels than groups treated with TPA alone (Fig. 2A), and tumors from TRPV1 / KO mice expressed the highest level of COX - 2 as a result of treatment with capsaicin and TPA together (Fig. 2A).

Residual tumors, spawned from the remaining cancer cells, were 3.5 times smaller in the treated mice than in untreated mice.

The team found that humans are equipped with tiny differences in a particular regulator of gene activity, dubbed HARE5, that when introduced into a mouse embryo, led to a 12 % bigger brain than in the embryos treated with the HARE5 sequence from chimpanzees.

The mice treated with rapamycin also ended up with better quality memory T - cells than the control mice.

LIPINDORA was given to near - term pregnant mice and the researchers found that the treated mice were significantly less likely than controls to have preterm uterine contractions or to deliver prematurely.

«What we found was, if we block mGluR5, which is the glutamate receptor we're interested in, the mice become hyper locomotive so they become able to move better than wild type mice suggesting glutamate receptors might be a good target for treating movement disorders such as Parkinson's disease.

The boost in survival time allowed the mice to live roughly 25 percent longer than those treated with radiation alone.

Dwarki notes that the weight has stayed off the treated mice for more than 8 months.

When we treat mice with resveratrol, it doesn't do anything other than make them sick.»

In the knockout mice, the virus replicated to higher levels than in those treated with the antibody, killing most of the fetuses.

Mice treated with antisense RNA (bottom) produced more dystrophin — colored red in this image — than did control mice (tMice treated with antisense RNA (bottom) produced more dystrophin — colored red in this image — than did control mice (tmice (top).

Mice treated with these viruses were less sensitive to painful stimuli than their untreated counterparts.

They plan to further optimize their protocol and follow their treated mice to see if they retain hearing longer than the two months already observed.

«We also carried out behavioral assessments which showed the treated mice spent more time on running wheels than the mice who aged without intervention.»

Philip Laipis of the University of Florida, who has also observed tumors in AAV vector - treated mice, agrees, at least for studies using a similarly high dose of AAV to target liver cells, which are more likely than other cell types to take up the AAV vector.

The treated mice developed much less severe symptoms and staved off illness for a longer period of time than did those that didn't receive the treatment.

They found that the phages from antibiotic - treated mice carried significantly higher numbers of bacterial drug - resistance genes than they would have carried by chance.

Treating mice with CK2 - ASO or housing them at 17 degrees C (62.6 degrees F) each prevented more than 25 percent of this weight gain.

DNA comparisons showed that mice treated with antibiotics had a higher proportion of bacteria belonging to the group Firmicutes than control animals.

When they were treated with leptin over the course of two days, control animals that weren't exposed to either chemical lost more weight than BPA - or DES - exposed mice.

When the mice were treated with the anthracycline doxorubicin, they survived more than normal mice and their heart function was completely preserved.

Spinal cord neuropathology showed higher pathology scores in demyelination, meningitis, perivascular cuffing (inflammation), and overall pathology in mice that had been given resveratrol during the early phase compared with mice fed a control diet, whereas mice treated with resveratrol during the entire treatment period had significantly higher pathology scores in meningitis and overall pathology than controls.

In 2009, US scientists discovered another effect: Mice treated with rapamycin lived longer than their untreated counterparts.

The treated mice lived an average of 36 days longer than untreated mice, and they were better at building nests, which reflects a combination of social behavior, cognitive performance and motor capabilities.

Importantly, levels of total tau and tau tangles in the brains of treated 12 - month - old mice were lower than in untreated 9 - month - old mice, suggesting that the treatment not only had stopped but reversed the buildup of tau.

When they exposed the treated mice to the influenza virus, the animals recovered from the illness even better than healthy mice infected with flu that had not undergone the treatment.

Mice treated with such combination therapy survived significantly longer than mice just treated with the Angiopoietin - 2 antibMice treated with such combination therapy survived significantly longer than mice just treated with the Angiopoietin - 2 antibmice just treated with the Angiopoietin - 2 antibody.

Surprisingly, while neither form of chemotherapy had any effect on the growth of these seeded metastases, Angiopoietin - 2 antibody treated mice had significantly less metastases in the lungs and in the bone and survived longer than untreated control mice.

The researchers discovered that mice inoculated with bacteria from the antibiotic - treated donors were indeed fatter than the germ - free mice inoculated with bacteria from untreated donors.

Cortical bone — one of the two types of bone tissue — was stronger in the treated mice than the controls, the researchers report online today in the Proceedings of the National Academy of Sciences.

The treated mice also grew fatter than the untreated mice when both were fed a high - fat diet.

These types of engineered tumors are much more difficult to treat than human tumors implanted in mice, because they suppress the immune response against them.

When researchers in Paul Kellam's group at the Wellcome Trust Sanger Institute exposed mice treated with Amphotericin - B to influenza A virus, the animals became very ill and lost more than 25 percent of their body weight.

Four weeks after transplanting these cells into the kidney cavities of mice with a form of kidney anaemia, the treated animals had blood EPO levels 20 times higher than those in controls (Science Translational Medicine, doi.org/cdmx).

In mice, the skin lesions that were treated with the nanosponge - hydrogel were significantly smaller than those that were left untreated.

The discovery may help explain why humans evolved more elaborate brains than mice, and it could suggest ways to treat disorders such as autism and epilepsy that arise from abnormal neural development.

Acute alcohol - treated FOXO3 - deficient mice developed more severe liver injury than that of wild - type mice, and this was attributed to decreased expression of autophagy - related genes.

The Wnt - treated mice had three - and - a-half times more bone in the injury site after 72 hours than the mice that received only saline, the team reports today in Science Translational Medicine.

Jaenisch's study comes hard on the heels of experiments in which mice with a Parkinson's - like condition were successfully treated using genetically - matched neurons created by cloning, rather than genetic reprogramming.

Female mice and male mice that had been treated with estrogen were able to clear the bacteria from their lungs more rapidly than normal male mice.

In mice, the dose required for contraception was 10 times lower than that required for treating Gaucher's disease patients.

The treated mice were able to run longer, maxing out at 15 minutes, than untreated ill animals, which managed only 10 minutes before becoming exhausted, the researchers report.

Last, spontaneous cage activity was more than 6-fold greater in IL - 15Rα — KO mice compared with B6129 control mice, and this amount of cage running activity was greater than that noted in other mouse models, including the HIF - 1α — KO mouse (45) and mice treated with PPAR agonists (46).

The experimental drug activated maternal PWS genes, and the treated mice had better growth and weight gain than untreated mice, with 15 percent surviving to adulthood without serious side effects.

When the researchers administered daily doses of BCX to mice before and after they injected the rodents with a nicotine - derived carcinogen, they found that the mice treated with BCX had fewer lung tumors than those that got no BCX.

The antibiotic - treated mice also showed more than a two-fold decrease in Aß plaques compared to controls, and a significant elevation in the inflammatory state of microglia in the brain.

By day 60, the average tumor volume in mice treated with tamoxifen plus CDB4124 was 70 percent lower than the original tumors.

One caveat is that actually, the untreated mice lived a little bit shorter than they «should» have by historical precedent, and the treated mice only lived as long as they «should.»