Sentences with phrase «than mouse brain»

The reconstruction of a non-human primate brain, with a volume 100 times larger than a mouse brain, is being considered for a later study.

It's so much bigger than the mouse brain, which is kind of an almond - size thing.

The group also found that the virus could be detected in fetal tissues other than mouse brain tissue, such as the lymph nodes.

This and subsequent similar experiments used guinea pig brains because they're larger and easier to work with than mouse brains.

Not exact matches

For all the human - mouse mixing, however, the rodents were no better learners than those with mouse - only brains.

These mice performed better than their normal counterparts on learning tests well into old age, and their brains did not exhibit the decline in neurogenesis typically seen in aged mice.

«We don't know if the observed reversibility of the disease symptoms as observed in the mouse,» he says, «exists in humans who have a much longer period of pre - and post-natal brain development than mice — months and years in humans, weeks in mice.»

The Salk team therefore took human brain organoids that had been growing in lab dishes for 31 to 50 days and implanted them into mouse brains (more than 200 so far) from which they had removed a tiny bit of tissue to make room.

Scientists imaged more than 1,700 mouse brains to build the most comprehensive mammalian brain map yet.

In 1999 van Praag showed that more new nerves formed in the hippocampus — one of the key centers in the brain for memory and learning — in physically active mice than in inactive ones.

When the researchers attached probes to the mice to measure brain activity, they found mice without ErbB4 had brain regions that were acting independently, rather than together in synchrony.

The behavioral tests used here modeled one dimension of the disease — an inability to experience pleasure from normal activities — but not others, such as stress and anxiety, and probably tap into different brain mechanisms in mice than in humans, he says.

In the study, led by post-doctoral fellow Long N. Nguyen of Duke - NUS, researchers found that mice without the Mfsd2a transporter had brains a third smaller than those with the transporter, and exhibited memory and learning deficits and high levels of anxiety.

The team found that humans are equipped with tiny differences in a particular regulator of gene activity, dubbed HARE5, that when introduced into a mouse embryo, led to a 12 % bigger brain than in the embryos treated with the HARE5 sequence from chimpanzees.

For instance, Evan's blue, a dye that stains the cellular protein albumin, penetrates the brain 10 times more efficiently in stressed mice than in unstressed mice.

«Mice that don't have these molecules seem to be able to change their brain circuits with experience much more rapidly than normal mice,» Shatz sMice that don't have these molecules seem to be able to change their brain circuits with experience much more rapidly than normal mice,» Shatz smice,» Shatz says.

Scientists imaged more than 1,700 mouse brains (injected with a tracer virus) at resolutions less than a micrometer, or 50 times smaller than a human hair.

David Holtzman of Washington University School of Medicine in St Louis, Missouri, and colleagues found that beta - amyloid levels were higher in mouse brains when the mice were awake than when they were sleeping.

When they next measured responses in the auditory regions of the brain, a more sensitive test, the mice responded to much quieter sounds: 19 of 25 mice heard sounds quieter than 80 decibels, and a few could heard sounds as soft as 25 - 30 decibels, like normal mice.

The HSP70 - boosted mice were much better than the others at finding their way around mazes, and post-mortems showed their brains to be free of the characteristic beta - amyloid plaques that clog the brains of people with Alzheimer's.

To investigate the longer - term effects of higher - than - normal acetylcholine levels on the brain, Hermona Soreq of the Hebrew University of Jerusalem and her colleagues first induced high levels of acetylcholine by forcing 26 mice to swim, an activity stressful to mice.

A dye used for more than a century to stain autopsied brain tissue can prevent the devastating effects of Huntington's disease in mice, new research shows.

«Caloric restriction in combination with low - fat diet helps protect aging mouse brains: Low - fat diet plus limited caloric intake prevented aging - induced inflammatory activation of microglia; exercise was significantly less effective than caloric restriction in preventing these changes.»

Stevens and her colleagues manipulated mice to make one eye more active than the other, creating a disparity in activity between the two neural circuits linking the eyes to the brain.

«I'm not saying that everyone who has influenza is cognitively impaired for 10 years,» he says, noting that human brains are much more complex than those of mice.

The mice received doses that were proportionally a thousand times greater than that given to people, along with a toxin that makes the blood - brain barrier leaky.

Removing a single gene from the brains of mice and zebrafish causes these animals to become more anxious than normal.

Brain changes in the mice lasted for more than four months, equivalent to years in humans.

A powerful X-ray tomography scanner allowed the researchers to image particularly thick sections of the brains of mice, which afforded them views into intact neural areas much larger than are customary in microscope imaging.

Then they injected the rodents» brains with Salmonella bacteria to cause an infection and waited to see whether the mice making the extra amyloid did better than controls at fighting off the microbes.

lost less weight, had fewer bacteria in their brains, and lived up to roughly 30 hours longer than the control mice

Once the microglia were mobilized in mouse models of Alzheimer's disease, the researchers observed a more than 60 percent reduction in amyloid beta in the brain.

Levels of A-beta in the blood of mice that received APOE2 were higher than in the other groups, suggesting that the protective variant had increased clearance of A-beta from the brain.

Mouse brains are physically smaller and grow faster than human brains.

When Gan imaged their brains, he found mice that had slept developed more dendrites — the tiny filaments that allow neurons to communicate — than did sleep - deprived mice.

The new study — published October 18, 2016 in the journal Molecular Psychiatry — combined genetic analysis of more than 9,000 human psychiatric patients with brain imaging, electrophysiology, and pharmacological experiments in mutant mice to suggest that mutations in the gene DIXDC1 may act as a general risk factor for psychiatric disease by interfering with the way the brain regulates connections between neurons.

When the mice died at 31 weeks, their brains had 20 % fewer neurons than normal mouse brains in regions that Huntington's strikes in people.

In a mouse brain, the CAQK peptide binds to injured sites more effectively than the control.

They found that germ - free mice broke down brain chemicals associated with anxiety, such as noradrenaline and dopamine, faster than did the other mice.

Young mice paired with old mice (left chart, two - toned) made fewer new cells in the brain's hippocampus than when paired with another young mouse (yellow).

Using novel technologies developed at HMS, the team looked at how a single sensory experience affects gene expression in the brain by analyzing more than 114,000 individual cells in the mouse visual cortex before and after exposure to light.

Importantly, levels of total tau and tau tangles in the brains of treated 12 - month - old mice were lower than in untreated 9 - month - old mice, suggesting that the treatment not only had stopped but reversed the buildup of tau.

Old mice made hundreds more new brain cells when paired with a young mouse (right chart, two - toned) than when paired with an old mouse (teal).

The microscopy techniques that permit imaging of brain cells in awake mice generally can't visualize anything deeper than a fraction of a millimeter below the brain's surface, whereas the mPOA is several millimeters deep.

Mice, for example, have brains that are around a thousand times smaller than the human one.

Well, human mating is a bit more complicated than it is for mice, and our perfumes have far less power over our brains (whatever the beliefs of pushy department - store perfumers).

As a result, the embryos carrying human HARE5 have brains that are 12 % larger than the brains of mice carrying the chimp version of the enhancer.

The blue stains in these developing mice embryos show that the human DNA inserted into the rodents turns on sooner and is more widespread (right) than the chimp version of the same DNA, promoting a bigger brain.

Now, Jennifer Rodger from the University of Western Australia in Crawley and colleagues have found that stimulating the brain at intensities lower than would make a neuron fire can remove unwanted neural connections in mice.

The authors also found abnormalities in the subthalamic nucleus occur earlier than in other brain regions, and that subthalamic nucleus nerve cells progressively degenerate as the mice age, mirroring the human pathology of Huntington's disease.