Sentences with phrase «than normal mice»

At the same time, the rodents had an even greater response to social defeat stress than normal mice do, suggesting their brains also are more susceptible to a depressive - like state.

Male mice from both strains lived 15 per cent longer than normal mice or females.

The scientists also noticed that Clock mice slept about one to two hours less than normal mice, and when they weren't sleeping, they were eating.

Scientists found that mice with a faulty internal Clock (right) gained more body fat than normal mice (left).

Both groups of animals are more resistant to insulin than normal mice are, the researchers discovered.

In subsequent tests, the mice with the mutation did a worse job than normal mice at learning new motor skills.

But when they looked at the activity in the bad NMDA channels, they found more in HD mouse brains than normal mouse brains.

The fact that Connexin 30 knockout mice had a higher number of grafted cells than normal mice, and that some of the grafted cells expressed CONNEXIN 30 is a very important finding when considering cell transplantation as a treatment for hereditary hearing loss caused by CONNEXIN deficiency.

When the researchers examined mice with disrupted IL - 27 function, they found that they were more likely than normal mice likely to die when infected with the virus, and that they died as a consequence of rampant lung inflammation.

Results showed the first two groups didn't develop PCOS, unlike the mice in the control group, whereas the test subjects with ovary ARs still contracted the disease, albeit at a lower rate than the normal mice.

To show why, he pulls out a raft of study results collected in a large three - ring binder and points to several studies showing that mice subjected to stress developed more cancers than normal mice.

Malcolm Eames of the BUAV says Harvard supported its patent application by claiming that tests of potential carcinogens would need fewer onco - mice than normal mice.

Mice engineered to lack REG3G and fed alcohol for eight weeks were more susceptible to bacterial migration from the gut to the liver than normal mice who received the same amount of alcohol.

This chocolate chia pudding (Mousse) looks like a sinful indulgence and yes is indeed incredible and rich and divine in every way but don't be fooled, its 100X more healthy than any normal mouse or pudding.

To their surprise, they found that these Th17 - deficient mice experienced far more aggressive cancer growth than normal mice — with the cancer completely smothering the lungs within 16 days.

In fact, the study, published recently online ahead of print in the journal Genes, Brain and Behavior, found these animals showed decreased aggressive behavior toward strangers and, instead, engage in more repetitive behavior than normal mice.

«Mice that don't have these molecules seem to be able to change their brain circuits with experience much more rapidly than normal mice,» Shatz says.

Experiments in mice injected with metastatic melanoma cells show that animals unable to produce Helios developed far fewer cancerous nodules in their lungs than normal mice did, and survived far longer.

They were also more sensitive to alcohol's effects than the normal mice were; studies have shown that the more sensitive a person is to alcohol, the less likely he or she is to abuse it.

But the males — despite having smaller testes and lower sperm counts than normal mice — were clearly fertile and produced offspring.

In the new study, Ji's group put SHANK3 - deficient mice through a battery of sensory tests, finding that the animals had lower sensitivity than normal mice to heat and heat - related pain — akin to the soreness a person feels after a sunburn.

The researchers found that mutant mice lacking Del - 1 had more severe attacks of the EAE than normal mice, with more damage to myelin, the fatty sheath that coats neurons and helps in the transmission of signals along the cell.

These mice prefer colder environments than normal mice and have wavier hair.

When the mice died at 31 weeks, their brains had 20 % fewer neurons than normal mouse brains in regions that Huntington's strikes in people.

Zeroing in on this kinase was encouraging, Goga said, because other researchers have shown that genetic - knockout mice that lack the entire family of PIM kinases are slightly smaller than normal mice, but «basically fine,» indicating that a drug targeting just PIM1 may have manageable levels of toxicity in breast cancer patients.

That indicates that they are less anxious than normal mice, the researchers report online today in the Proceedings of the National Academy of Sciences.

For one thing, not all descendants were easier to startle than normal mice — it's not known why.

Mice genetically engineered not to produce a key cytokine (TNF - alpha) fared no better than normal mice during infections.

The quest for better opioids got a much - needed jolt in 1999, when researchers at Duke University showed that mice lacking a protein called beta - arrestin 2 got more pain relief from morphine than normal mice did.

KLF15 - deficient mice produced 40 to 50 percent less bile acid than normal mice, making them less capable of absorbing the lipids and the nutrients they contained.

The scientists found that transgenic mice in which phospholipase Cγ1 was unlinked from the TrkB receptor were less susceptible to seizures than normal mice.

Sinclair's lab is now working on developing what he calls a possible «supermouse» with elevated levels of NAMPT to see if it lives longer and is more disease - resistant than normal mice.

The resulting mice had the prairie voles» receptor distribution in their limbic systems; and although not monogamous, they were more devoted than normal mice to female cagemates, showing some of the other vole's eagerness in sniffing and grooming.

The drugs were identified by screening the St. Jude library of 7,389 compounds looking for ones that targeted group 3 mouse tumor cells rather than normal mouse brain cells.

In another experiment, mice lacking the cells that produce serotonin scratched less than normal mice when exposed to a skin irritant.

REG3G - deficient mice also developed more severe alcoholic liver disease than normal mice.

When they removed the gene that codes for POU6F2, the affected mice had thinner corneas than normal mice.

They also found that mice genetically altered to have reduced AIM2 function, when treated with the chemicals, showed significantly more tumors than normal mice.

However, they also developed softer bones, more infections, and more cataracts than normal mice.

Gordon and his team found several years ago that genetically obese mice (the animals lacked the ability to make leptin, a hormone that limits appetite) had 50 percent fewer Bacteroidetes bacteria and 50 percent more Firmicutes bacteria than normal mice did.

Experiments in Muc1 knockout mice and mice with Muc1 knockdown have shown that under Helicobacter infection, mice deficient in Muc1 develop far more cancer - promoting inflammation than normal mice.

I also jumped into Project 1999 with some friends and nearly forgot that I was playing the game with something other than a normal mouse.

Mice lacking a key cilia protein appear to have dulled heat and touch perception, they further discovered: These animals left their tails in hot water baths significantly longer than normal mice did, and they responded more slowly to pokes of their hind paws.

Mice with a disrupted biological clock slept less, ate more, and gained more body fat than normal mice, indicating that, when it comes to understanding the molecular basis of obesity, timing may be key.

Older modified male mice metabolised sugar faster than normal mice and females, suggesting that SIRT6 might extend life by protecting against metabolic disorders such as diabetes.

Several years later, Turek's team noticed that mice that lacked a functioning Clock gene were heavier than normal mice.

The mice also held fewer beta cells and secreted less insulin than normal mice.