Sentences with phrase «than normal mice when»

In another experiment, mice lacking the cells that produce serotonin scratched less than normal mice when exposed to a skin irritant.

Not exact matches

Aside from a food intake in laboratory mice that's about 40 percent fewer calories than normal, however, it's been found that another way to activate this pathway is with rapamycin, which appears to have a significant impact even when used late in life.

When they next measured responses in the auditory regions of the brain, a more sensitive test, the mice responded to much quieter sounds: 19 of 25 mice heard sounds quieter than 80 decibels, and a few could heard sounds as soft as 25 - 30 decibels, like normal mice.

These modified mice had significantly smaller testes and lower sperm counts than their normal counterparts — and when the group bred them with normal females, they found that the litter size was around half normal.

When the researchers examined mice with disrupted IL - 27 function, they found that they were more likely than normal mice likely to die when infected with the virus, and that they died as a consequence of rampant lung inflammatWhen the researchers examined mice with disrupted IL - 27 function, they found that they were more likely than normal mice likely to die when infected with the virus, and that they died as a consequence of rampant lung inflammatwhen infected with the virus, and that they died as a consequence of rampant lung inflammation.

The NK1R - deficient mice consumed far less alcohol — especially later in the trial when alcohol concentration was higher — than the normal mice did.

Using mice in which the production of the enzyme was blocked, the researchers found that mice lacking FIH in their muscles require more oxygen than normal when exercising.

When the researchers then induced stroke in mice either with or without the PARP gene, they found that the resulting tissue damage in the mice without the enzyme was 80 % less than in normal mice.

When the mice died at 31 weeks, their brains had 20 % fewer neurons than normal mouse brains in regions that Huntington's strikes in people.

When they exposed these mice to the cold, the animals developed far fewer beige fat cells than did normal animals, suggesting that macrophages were key to browning of white fat.

When the mice were treated with the anthracycline doxorubicin, they survived more than normal mice and their heart function was completely preserved.

Mice with a disrupted biological clock slept less, ate more, and gained more body fat than normal mice, indicating that, when it comes to understanding the molecular basis of obesity, timing may be Mice with a disrupted biological clock slept less, ate more, and gained more body fat than normal mice, indicating that, when it comes to understanding the molecular basis of obesity, timing may be mice, indicating that, when it comes to understanding the molecular basis of obesity, timing may be key.

The scientists also noticed that Clock mice slept about one to two hours less than normal mice, and when they weren't sleeping, they were eating.

On the other hand, as they aged, these «knockout mice» grew fatter than the normal mice, especially when fed a high - fat diet.

The quest for better opioids got a much - needed jolt in 1999, when researchers at Duke University showed that mice lacking a protein called beta - arrestin 2 got more pain relief from morphine than normal mice did.

The fact that Connexin 30 knockout mice had a higher number of grafted cells than normal mice, and that some of the grafted cells expressed CONNEXIN 30 is a very important finding when considering cell transplantation as a treatment for hereditary hearing loss caused by CONNEXIN deficiency.

And, consistent with other studies, when these mice ate a high - fat diet, they gained weight faster than their normal counterparts.

When the researchers injected extra copies of the betatrophin gene into the liver of normal mice, the animals» pancreases responded by making as much as 30 times more β cells than usual.

Yet when Evans and his colleagues recently gave a PPAR & # 948 - boosting drug to normal adult mice, the rodents developed no greater stamina than nondoped counterparts — until the researchers had the animals combine the drug with a workout routine.

Earlier studies had suggested that animals — including fruit flies, dogs and mice — live longer when they ate about 25 percent fewer calories than normal.

When the researchers induced wounds in these mice, they found that the mice without TSP2 healed significantly better and faster than other mice that had diabetes along with normal levels of TSP2.

They also found that mice genetically altered to have reduced AIM2 function, when treated with the chemicals, showed significantly more tumors than normal mice.

But the mice were fed food containing higher - than - normal levels of the heavy isotope so that when the mice ate this food, their bodies absorbed the nitrogen isotopes and used it for several purposes, including to make GFAP molecules.

But when they looked at the activity in the bad NMDA channels, they found more in HD mouse brains than normal mouse brains.

Remarkably, outcomes following loss of the switch mirrored what the group had previously observed when they physically removed the gene itself: the lungs of mutant mice contained many more melanoma cells than did lungs of normal mice.