Sentences with phrase «than risk treatment»

A few of these cases are so far advanced that it is safer to simply treat the organ damage rather than risk treatment to kill the worms.

Not exact matches

Risk management coverage and assurance mapping: Is each material financial and non-financial risk (no more than 12 - 15) covered (via explicit mapping) through identification, treatment, independent assurance and upward reportRisk management coverage and assurance mapping: Is each material financial and non-financial risk (no more than 12 - 15) covered (via explicit mapping) through identification, treatment, independent assurance and upward reportrisk (no more than 12 - 15) covered (via explicit mapping) through identification, treatment, independent assurance and upward reporting?

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Sadly, Hitchens's treatment of addiction fails to recognize the various ways in which addiction impacts the will, and rather than empowering addicts, his position runs the risk of encouraging people to abandon them to their own diminished willpower.

Even if Sturridge was available on the cheap, which is pretty likely considering his injury record, can Arsenal really afford to take the risk of having another member of the squad spending more time in the treatment room than on the pitch?

There are times when it would be dangerous to breastfeed during an illness such as when the treatment for the illness carries a higher risk to the baby in the mother's milk than not breastfeeding would.

I've done homebirths [in the UK] and the potential for irreparable disaster was present at every one, although there was a crisis in only one [abruption] and mother and baby were both saved, they were also at much greater risk at home than in the hospital and in the end required much more intensive treatment [largely because of time delays] than if the same situation had happened in hospital.

Also, the risk of spontaneous abortions in practitioners after the tenth week of pregnancy was significantly increased when they gave deep - heat treatments (for strain injuries or as mobilisation therapy) for more than five hours a week, and ultrasound for more than 10 hours a week.

«Morning Joe» host Joe Scarborough issues a warning to AG Andrew Cuomo today, saying he should change his media strategy or risk harsher - than - usual treatment from the Capitol press corps when and if he becomes governor.

«Rather than educating youth about the dangers of opioids, focusing on getting hardened drug dealers poisoning our children off the streets, and offering addicts effective treatment, we will instead signal to users that addiction is a manageable condition and you can partake in illegal opioid use nearly risk - free.»

One of the studies, published in 2008, suggested that patients whose antiretroviral treatment was deferred until their CD4 cell counts were below 250 were at greater risk of opportunistic infection than those that received antiretroviral treatment when CD4 cell counts were higher than 350.

Active surveillance involves regular testing to check for cancer growth rather than immediate treatment, and many patients with low - risk prostate cancer on active surveillance may be able to avoid treatment for several years or altogether.

Previous studies also demonstrate that moderate hypo - fractionated radiation therapy (HRT), consisting of daily treatment for one month using a larger dose per treatment, provides a similar low risk of recurrence, and may even be lower with HRT than CRT.

However, during and after the treatment of breast cancer, having optimal control of heart disease risk factors is important, because older breast cancer survivors are more likely to die of heart disease than breast cancer,» Dr. Mehta said.

Breast cancer was first associated with combined HRT treatment in 2003, when a large US trial found that the risk of developing breast cancer was 1.26 times higher for women taking HRT than those who weren't.

Generally, however, studies in children must meet a higher standard than adult trials in protecting children from risk, particularly if the treatment has little chance of providing benefit.

Another problem is that modeling studies, like this one, are inherently less powerful than other kinds of medical research: randomized clinical trials, the gold standard in medical research, in which patients are randomly assigned different treatments or no treatment; case - control studies, which compare patients who have a condition with those who do not; or cohort studies, which determine the risk of contracting a disease by studying a group of people with similar demographics.

Since children of mothers with preclinical RA also had an increased risk of epilepsy, Rom said the findings point towards an important role of the disease itself rather than an effect of treatments for RA.

Many studies show that these patients are at increased risk of infertility and are less likely than normal - weight women to conceive after fertility treatment.

Instead, researchers told the European Breast Cancer Conference that their findings suggest that extending screening programs to older women results in a large proportion of women being over-treated, and at risk from the harmful effects of such treatment, because these women were more likely to die from other causes than from any tumors detected in the early stages of growth.

«It may be the treatments used for migraines that are responsible for this risk reduction rather than the migraine itself,» says study co-author Christopher Li, a cancer epidemiologist at Fred Hutchinson Cancer Research Center in Seattle.

According to Dr Emberson, «Although alteplase increased the risk of death from intracranial haemorrhage by about 2 % within the first few days after stroke, by a few months survivors treated with alteplase were less likely to be disabled than those not receiving such treatment.

Further, the study confirmed earlier studies that found a twofold increase in heart attack risk shortly after treatment began in men older than 65.

«However, if hormonal treatment is taken more than 10 years after menopause, the cardiovascular risk is effectively increased.

«We're really strongly recommending them for treatment rather than prevention,» said Schuchat, stressing that prophylaxis should be reserved for people who are at high risk for severe disease.

* The ACC / AHA cholesterol treatment guideline recommends prescribing the strongest statins at high doses to most men older than 65, even those with no history of heart disease, or any major risk factor for heart attacks, and with normal cholesterol levels.

«When used in the right context, specifically in postmenopausal women younger than 60 years old for whom the benefits outweigh risks, menopausal hormonal therapy is effective for both the prevention and treatment of osteoporosis,» said the study's first author, Georgios Papadakis, MD, of the Lausanne University Hospital in Lausanne, Switzerland.

Volunteers are often more than willing to accept those risks if the experimental intervention offers potentially more promising treatment for their condition, compared with what is on the market.

Egg donation, like IVF and ICSI, is considered a safe treatment, despite the older age of patients, but a new study from France has found that the pregnancies of egg donation patients are at a higher risk of disorders — particularly relating to high blood pressure — than the pregnancies of routine IVF patients using their own eggs.

Our aim was to find out whether pregnancies from egg donation are genuinely associated with a higher risk of hypertension and pre-eclampsia than those from treatments using the patient's own eggs.

«So the exact mechanisms behind the observed increase in risk are still unknown,» explained Dr Jensen, «but it is generally believed that underlying infertility has a more important role in adverse effects in the offspring than the treatment procedures.

Significant anti-tumor activity was observed as well: nearly 70 percent had a near complete or complete response within three months post treatment, which compares favorably with the expected responses (less than 40 percent) in patients without high - risk disease following an ASCT.

Numerous studies suggest that Colón, Nitkowski and others trying untested stem cell treatments may be risking more than they think.

During an average follow - up time of more than seven years, lithium treatment was associated with the lowest risk of rehospitalisation in mental or physical disease, with a risk reduction of about 30 per cent compared with no treatment at all.

In a study that included more than 71,000 stroke patients, implementation of a quality initiative was associated with improvement in the time to treatment and a lower risk of in - hospital death, intracranial hemorrhage (bleeding in the brain), and an increase in the portion of patients discharged to their home, according to the study appearing in the April 23/30 issue of JAMA, a neurology theme issue.

I think that, with more sick people coming to our treatment centres rather than staying in the community and risking spreading the virus, and with continued education, we will see a big change in the situation.

For instance, recent trials show that if people are treated when their blood contains 350 to 500 cells per cubic millimetre, their risk of transmitting the virus is 96 per cent lower than if they begin treatment when their counts fall below 350.

In order to determine which treatment is most effective, researchers at Karolinska Institutet compared the risk of re-admission to hospital in more than 18,000 patients in Finland who had previously been hospitalised for bipolar disorder.

A higher risk was also seen for both ischemic and haemorrhagic stroke if the treatment was initiated later than five years after the onset of menopause and contained conjugated equine oestrogens.

In such cases, blacks are at significantly higher risk than whites of not receiving treatment for the cancer that in many cases would be effective.

Women who reported continuous or remote past HT use had less pronounced kyphosis by the time they were in their mid-80s than never - users, supporting the argument for HT as a possible early postmenopause treatment for women concerned about their posture and fracture risk.

The study, which published today in the Journal of Investigative Dermatology, is the first to link psoriasis severity to an increased risk of death using an objective measure of disease severity — called Body Surface Area (BSA)-- rather than treatment patterns, such as whether or not a patient was receiving oral, injectable or phototherapy treatment for the condition.

Rather than playing recordings for healthy babies, Partanen sees potential treatments for children at risk for dyslexia or auditory processing disorders, if hearing certain sounds in pregnancy turns out to speed up language learning — «but that's a big if.»

This is a desirable feature for a helper drug as it would reduce the risk of treatment failure due to factors other than antibiotic resistance (e.g. biofilms, immunosuppression, etc.), allow dose reduction for toxic antibiotics such as colistin, and possibly even prevent selection of resistant mutants» says Guardabassi.

November 15, 2006 Risk after colon cancer higher for very fat and very thin Even after successful treatment for colon cancer, the very obese are about one - third more likely to have their cancer recur and to die prematurely from cancer than those of normal weight, researchers from the University of Chicago and the University of Pittsburgh report in the November 15, 2006, issue of the Journal of the National Cancer Institute.

«For prescription opioid dependence, buprenorphine detoxification is less effective than ongoing maintenance treatment, and increases the risk of overdose and other adverse events,» said Fiellin.

Based on an evaluation of nearly 22,000 women included in the WHI trials, women aged younger than 40 years already in menopause had significantly higher risks for fracture than women who experienced menopause between the ages of 40 and 49 or after 50, regardless of treatment intervention.

Most professional societies recommend targeting HbA1C levels less than 6.5 or 7 percent, with individualized treatment targets based on patient age, other medical conditions, and risk of hypoglycemia with therapy.

That means that the more likely application of genetic testing in testicular cancer is in diagnosing the level of risk in men yet to develop it, rather than in matching patients to specific treatments.

The effect of glucocorticoid treatment is most prominent on trabecular bone and is therefore likely to be larger on vertebral bone than on hip bone.3 Glucocorticoids are associated with an increased rate of fracture, and higher doses and longer use of glucocorticoids are associated with higher risks of fracture.4 Compared with patients not taking glucocorticoids, the risk of hip and vertebral fracture among patients taking glucocorticoids is increased by 60 % and 160 %, respectively.4 Among 80 - year - old patients, the hip fracture risk is increased by a magnitude of 2.1 and is independent of BMD.5 Most studies indicate that fracture risk is increased following at least 3 months of treatment with daily doses of 5 mg of prednisolone or more in older men and women.4