Sentences with phrase «than silence genes»

C2c2 should be able to do more than silence genes.

Not exact matches

Using the new data, Laura Carrel, a geneticist at Pennsylvania State College of Medicine in Hershey, and Huntington Willard, a geneticist at Duke University in Durham, North Carolina, discovered that 15 percent of the genes on the inactivated X chromosome are actually not silenced — and most are likely to be expressed at higher levels overall in women than men.

Gore and her colleagues believe these effects are epigenetic; that is, rather than inducing genetic mutations, which would change the sequence of the rats» DNA, the fungicide is permanently silencing or reprogramming normal genes that control development and behavior.

Less than a decade after a powerful gene - silencing method — RNA interference, or just RNAi — was discovered, the field's pioneers have not only won the 2006 Nobel Prize in Physiology or Medicine but have also helped launch an entirely new class of drugs into human clinical trials.

When the researchers silenced the control gene, the engineered tobacco plants had up to 85 % less trienoic fatty acids in their chloroplasts than normal.

Recent innovations have made it easier than ever to «knock out» or silence the expression of selected genes.

Both mice and humans with a silenced FMR1 gene have malformed neurons: Spines on their dendrites are longer, thinner, and more numerous than normal, and they also transmit weaker electric signals.

What these groups are attempting basically is «gene silencing», with a twist - it's aimed directly at the DNA, rather than targeting a «message molecule» called RNA.

The scientists noticed several abnormalities in the heart cells created from the patients: the cells beat weaker than normal, and numerous genes in the cells were abnormally activated or silenced.

A group of scientists has redesigned and tested a harmless virus that can efficiently deliver a «gene silencing» message throughout the brain in mice, much further than naturally occurring viruses can reach.

They discovered that CRISPRi was much more efficient than CRISPR - Cas9: in more than 95 % of the cells created using CRISPRi, the target gene was silenced, compared with only 60 - 70 % of cells grown from CRISPR - Cas9.

Comparing this approach to the classic CRISPR / Cas9 system designed to cleave the DNA, the Gladstone team found that CRISPRi is actually more effective, silencing the target gene in more than 95 percent of cells, compared with the 60 percent to 70 percent efficiency of CRISPR / Cas9.

Women who ate less than a thousand carb calories per day during the early part of pregnancy were more likely to give birth to babies with an overly silenced gene for the Vitamin A receptor RXR - alpha.