Infusing the mice with massive numbers of these plasmids under high pressure left the animals with up to 92 % less hepatitis B RNA
than control animals, the researchers report in the 12 May issue of Nature Biotechnology.
A day after fear training, animals whose brains were injected with a virus engineered to carry a «sponge» against miRNA - 34a froze less often
than control animals.
The animals with the mutation fell off a rolling log much sooner
than the control animals did, which suggests that the mutation left them much less tolerant to alcohol's effects.
The analysis found the mice that were exposed to BPA had a significant decrease in beta cell mass and lower levels of insulin secretion
than the control animals.
The verdict, from a 25 - year study in rhesus monkeys fed 30 % less
than control animals, represents another setback for the notion that a simple, diet - triggered switch can slow ageing.
When pressure overload was surgically induced, the transgenic mice developed significantly less ventricular hypertrophy
than control animals.
DNA comparisons showed that mice treated with antibiotics had a higher proportion of bacteria belonging to the group Firmicutes
than control animals.
The mice that received dengue or West Nile antibodies also had higher levels of Zika virus in their testes and spinal cords
than control animals did.
Mice that were previously exposed to early - life stress performed worse
than control animals and demonstrated poor learning and memory skills.
When fed a standard soybean diet, the transgenic pigs excreted up to 75 % less phosphorous
than control animals, the researchers report in the August issue of Nature Biotechnology.
The microbiome did modulate the immune system: the animals grown in germ - free conditions expressed complement genes at lower levels in the skin
than control animals.
But the third had striking effects: males with this variant had significantly lower sperm counts
than control animals.
Those animals, the researchers found, are more much sensitive to insulin's blood sugar - lowering effects
than control animals.
Even insects that ate GDL but no pathogen died sooner
than control animals, their bodies ravaged by opportunistic microbes.
In an operant test R6 / 2 transgenic mice (240 - CAG repeats, B6 congenic background) were less able to acquire lever pressing
than control animals at an age where motor function is only mildly affected (from 9 weeks), with this deficit being both more pronounced and detected earlier (from 5 weeks) where reinforcement was not solely contingent on responding.
Animals that were also given a plasma kallikrein inhibitor, and animals that were genetically modified to produce lower amounts of the protein, showed significantly less bleeding, brain swelling and damaged brain areas
than control animals without plasma kallikrein blockade.
Not exact matches
The plant is less coordinated as a subject
than an
animal and is more like a democracy of cells in which no particular group of cells has a central
control.
The
animals that survive today occupy less
than 1 per cent of that range — and live in carefully
controlled areas.
Strategies that boost the cell's quality
control programs, rather
than disarm specific pathologic proteins, have looked promising in lab
animals that serve as models for human neurodegenerative disorders including Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia.
After
controlling for the availability of the
animals, the scientists calculated that vampire bats were seven times more likely to feed on pigs
than chance would predict, the team reports in the current issue of the Journal of Mammalogy.
When injected with cancer cells,
animals housed there developed tumors 80 % smaller
than those in
control mice, or no tumors at all.
The
animals that got microbes from the gastric bypass donors lost about 5 % of their body weight in 2 weeks — even though they weren't eating any less
than controls.
The department's
Animal and Plant Health Inspection Service oversees more than 7800 animal holding facilities from zoos to circuses and aquariums, including roughly 1100 labs, some of them run by the National Institutes of Health, the Food and Drug Administration, and the Centers for Disease Control and Preve
Animal and Plant Health Inspection Service oversees more
than 7800
animal holding facilities from zoos to circuses and aquariums, including roughly 1100 labs, some of them run by the National Institutes of Health, the Food and Drug Administration, and the Centers for Disease Control and Preve
animal holding facilities from zoos to circuses and aquariums, including roughly 1100 labs, some of them run by the National Institutes of Health, the Food and Drug Administration, and the Centers for Disease
Control and Prevention.
Several years ago, while creating a genetically engineered mouse that expresses high levels of the mouse HMGA1 gene to investigate its role in leukemia, Resar and her colleagues made the chance finding that the intestines of these
animals were much larger and heavier
than those of «wild - type»
animals (or
control mice that were not genetically modified).
Within four weeks, EPO levels in the blood of treated
animals were 20-fold higher
than in
controls.
More and larger skin tumors sprouted in
animals lacking HSF1
than in
controls, the scientists report in the 21 September issue of Cell.
When they were treated with leptin over the course of two days,
control animals that weren't exposed to either chemical lost more weight
than BPA - or DES - exposed mice.
«Any flying
animal larger
than a large insect will need to use some kind of
controlled stall or hover mechanism to land,» he says, but the new track «does not give us any new information about launch».
As the scare widens, so does the probe: The Food and Drug Administration (FDA) says it is considering regulatory changes to tighten
controls and is investigating whether any of the contaminated wheat gluten — which is implicated in more
than 100
animal deaths — made it into food consumed by humans.
The rats that were forced to exercise had immune responses 20 % to 30 % weaker
than those of
control animals that didn't exercise at all, while the immune responses of the
animals that exercised by choice were enhanced.
«We observed that the virus in all vaccinated
animals initially replicated less
than in the
control group,» Ulrike Sauermann, first author of the study, summarized the results.
Zoo veterinarians have been attempting, with varying degrees of success, to castrate the 2 - ton
animals for more
than 90 years, in hopes of
controlling the size of captive populations and reducing the number of fights between the males of this aggressive species.
Four weeks after transplanting these cells into the kidney cavities of mice with a form of kidney anaemia, the treated
animals had blood EPO levels 20 times higher
than those in
controls (Science Translational Medicine, doi.org/cdmx).
Instead of slowly adding material molecule by molecule, the coral
animal actively constructs large chunks of minerals that it adds to its growing skeleton, helping it grow much faster
than it otherwise could, and with greater
control.
The extent of IAPP amyloid deposition in Tg / Tg mice was, at all time points, significantly higher
than the staining observed in Tg - hIAPP
animals inoculated with
control pancreas homogenate (Fig. 3 F).
Fewer eggs can cause early menopause in women Even before puberty the egg reserve was smaller in the exposed
animals than in the
control animals.
In theory, it would be possible to extract these particles from
animals for use in humans, but the process would likely be far more complicated
than creating them synthetically in a
controlled environment as Gianneschi and his team have done.
The insulin - receptor knockout mice developed cholesterol plaques that were more
than twice the size of those found in the
control animals.
In contrast to embryos, lipid - containing structures in intestinal and epidermal cells of adult W01A8.1 null mutants (Figs. 5J and 5L) were smaller
than lipid - containing structures in
control animals (Figs. 5I and 5K).
The average proportion of CD4 and CD8 positive T cells in Type III -, but not Type I -, infected
animals were much higher
than uninfected
controls, reflecting ongoing brain inflammation.
Percent eosinophils was lower in these vaccinated
animals (mean 1 — 3.2 %)
than had been seen in
animals given VLP vaccines in the earlier study (mean 13.2 ± 9.6 % and 22 ± 9.9 % of cells for VLP with PBS or alum, respectively in that study) but no (0 %) eosinophils were seen in the lung infiltrates of
control animals in this experiment.
Furthermore, in the obese descendant group insulin levels were higher
than in the
control animal group, independent of sex.
It's not known whether the leashes in the Shuwaymis rock art panels are literal or symbolic, but it certainly suggests these Holocene hunters had a lot of
control over their dogs, that some dogs could have been more valuable
than others (and therefore kept closer), and that the people likely bred and trained these
animals.
The Human Emulation System offers researchers a new standard for predicting how a human may respond to diseases, medicines, chemicals, and foods — with greater precision and
control than today's cell culture or
animal - based testing approaches.
Although body weight was not different, liver weights were significantly higher (P < 0.01) in 15 - mo - old mice derived from IVC in the presence of FCS
than in
control animals (Supplemental Table S2); this phenotype was transmitted to F1 and F2 males derived from F0 IVC males but was not transmitted to F1 females.
A higher percentage of Tregs was detected in tolerant
animals than in
controls, which is consistent with tolerance.
ELISPOTS in tolerant
animals were similar to those from
control mice (p > 0.05) but significantly lower
than those in sensitized mice, p < 0.05 (Figure 7h).
Visual acuity tests showed that the performance of
animals receiving iPS - RPE transplants was significantly better
than sham - operated and
control animals.
Grafts from tolerant
animals had an average of 17 positive cells per 120 CD4 + cells on histological sections, compared to less
than 1 in both the rejected or the syngeneic
controls, suggesting a role for Tregs in HPC - induced tolerance.
An Arabian study found that ginger extracts suppressed the growth of breast cancer cells, while an
animal study at University of Minnesota showed that mice with colorectal cancer that received gingerols had 75 percent fewer tumors
than the
control group.