Not exact matches
These risks and uncertainties include,
among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways
than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an
increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.
The OECD reports that since 1999, normal pension ages
among its member countries
increased by more
than two years.
Among the top 20 MBA programs in the U.S., at least four schools — Yale, Harvard, Northwestern, and UCLA — have
increased their average scholarship payouts to students by more
than 100 % since the 2004 - 2005 academic year.
Among the top five cryptocurrencies by market capitalization, ripple has fared the worst, down more
than 74 percent this year following an epic 35,000 percent
increase in 2017, according to CoinMarketCap.
Among the factors that could cause actual results to differ materially are the following: (1) worldwide economic, political, and capital markets conditions and other factors beyond the Company's control, including natural and other disasters or climate change affecting the operations of the Company or its customers and suppliers; (2) the Company's credit ratings and its cost of capital; (3) competitive conditions and customer preferences; (4) foreign currency exchange rates and fluctuations in those rates; (5) the timing and market acceptance of new product offerings; (6) the availability and cost of purchased components, compounds, raw materials and energy (including oil and natural gas and their derivatives) due to shortages,
increased demand or supply interruptions (including those caused by natural and other disasters and other events); (7) the impact of acquisitions, strategic alliances, divestitures, and other unusual events resulting from portfolio management actions and other evolving business strategies, and possible organizational restructuring; (8) generating fewer productivity improvements
than estimated; (9) unanticipated problems or delays with the phased implementation of a global enterprise resource planning (ERP) system, or security breaches and other disruptions to the Company's information technology infrastructure; (10) financial market risks that may affect the Company's funding obligations under defined benefit pension and postretirement plans; and (11) legal proceedings, including significant developments that could occur in the legal and regulatory proceedings described in the Company's Annual Report on Form 10 - K for the year ended Dec. 31, 2017, and any subsequent quarterly reports on Form 10 - Q (the «Reports»).
In addition to this secular shift in portfolios, a paper published by the Kansas City Fed predicts a gradual overall
increase in bond ownership
among people older
than 65 compared to the same age group in previous years.
The average premium for employer - sponsored family coverage
among firms with fewer
than 200 employees
increased 5 percent to $ 16,625 compared with the prior year, according to a Kaiser Family Foundation survey.
More
than 44 percent of survey respondents reported a worsening work ethic
among recent graduates, and nearly 38 percent reported an
increase in the number of unfocused employees.
Natural Gas Natural gas futures were
among the quarter's key decliners -LRB--7.5 %, to US$ 2.73 per million British thermal units) as production growth outweighed seasonal consumption and higher exports of the fuel.1 Spot prices saw an even larger drop of 20.6 % (to US$ 2.81) as the support of December's weather - related demand spikes faded and a more normal winter pattern developed.1 Natural gas generally took its downward price cues from elevated US production and growth in the natural gas - focused rig count, which
increased from 179 to 194 in March alone.2 Despite the price drop, traders remained optimistic given surging US shale - gas exports and a supply deficit that was 20 % larger
than the five - year average at March - end, the biggest in four years.3 Moreover, total natural gas inventories of 1.38 trillion cubic feet were nearly 33 % below their year - ago level.3 Meanwhile, the market appeared focused on an anticipated production surge (2018 is projected to be a record growth year for gas supplies) and may have overlooked intensifying demand as US exports increasingly helped drain supplies.
And
among the approximately 1,000 firms that buy back shares and report R&D spending, the proportion of net income spent on innovation has averaged less
than 50 percent since 2009,
increasing to 56 percent only in the most recent year as net income fell.
According to a 2016 study published by the Harvard Business Review, including more
than one woman or member of a racial minority in a finalist pool helps combat unconscious bias
among interviewers and
increases the likelihood of a diverse hire.
The average one - year rate on certificates of deposit
among the top nationwide banks
increased by more
than 2 percent, to 0.88 percent from 0.86 percent.
In 2011, corporate spending
among the Global Innovation 1000
increased 9.6 percent over the previous year, slightly faster
than the 9.3 percent gain in 2010.
Among the major transfers to persons, lower -
than - expected employment insurance benefits should more
than offset an
increase in children's benefits.
Even in New York City, where the financial sector, which employs relatively few blacks, has shed tens of thousands of jobs, unemployment has
increased much faster
among blacks
than it has
among whites.
Export Ready, Export Critical: Music Publishing in Canada, found that sales outside Canada have become a major driver of sector growth, resulting in more
than C$ 120 million in revenue
increase among Canadian Music Publisher Association members since 2005.
A slight
increase in enthusiasm for Trump is found
among households with a combined income over more
than $ 100,000.
Given the growing scarcity of available collateral
among bond dealers, a collapse in repo liquidity, and
increasing frequency of delivery failures, all of which is shorthand for a bond market that is becoming less liquid — it seems that QE has begun to create, rather
than relieve, meaningful constraints.
The population grew by more
than 2 percent two years in a row, and its 3.6 percent employment growth
increase easily ranks
among the survey's biggest.
Among youth — who use e-cigarettes at higher rates
than adults do — there is substantial evidence that e-cigarette use
increases the risk of transitioning to smoking conventional cigarettes.
Kosher food pantries report growing need A 2011 survey of Jewish New Yorkers revealed that Jewish poverty has risen in the past decade and
increased at a faster rate
than poverty
among other groups.
Oddly enough, the rate of women reporting more
than 100 partners declines from 4 percent
among the high school graduates to one percent
among college graduates but
increases to 8 percent
among postgraduate women.
Among more
than 300,000 queries, notable
increases include topics like the plans God has for us (up from No. 106 to No. 14), false prophets (up from No. 167 to No. 13), trust no man (up from No. 50 to No. 18).
Dreweke pointed to a study detailing the
increased use of long - acting reversible contraceptives (such as IUDs and implants)
among teens; although the study was only conducted
among women who already used contraception, the efficacy of longer - acting contraceptives is higher
than those of other birth control methods.
The report found,
among other things, that 43 of the lower 48 U.S. states have set at least one monthly heat record since 2010, sea levels are expected to rise between one and four feet by the end of this century, winter storms have
increased in intensity and frequency, and the past decade was warmer
than every previous decade in every part of the country.
If the shift away from defined - benefit pension plans caused the
increase in mortality, then one would expect to see the opposite relationship between education and mortality: there would presumably be an
increase in mortality
among the more - educated in this group of Americans
than among the less - educated, given that it is the more - educated who have disproportionately lost defined - benefit retirement pensions.
Tapping into a growing consumer trend that has attracted the attention and support of meat industry titans like Tyson Foods, who own a 5 % stake in Beyond Meat, the expansion into Kroger marks a more
than tripled distribution growth of The Beyond Burger within two months» time and reflects an
increased demand for plant - based protein
among mainstream consumers.
Income from the sale of timber has doubled, and
among those communities that have taken control of forest harvesting, revenues have
increased more
than five-fold, a tremendous improvement that lays the foundation for further investment in CFE development.
2017 - 18 Prize Money Fund: UEFA Champions League is by far the highest prize money paying competition in the world, yeah thats right even more
than Football World Cup and for 2017 - 18 season we see another 10 %
increase compared to 2015 - 16 season where $ 1.257 billion was distributed
among teams in champions league from playoffs to the winners.
Among boys more
than two - thirds reported changing their eating to
increase their muscle size or tone, including 11.6 % who did this often, and more
than 90 % who exercised more, four out of ten who reported doing so often.
Research tells us that demand feeding, rather
than the scheduled feeding that often comes with expressing, results in
increased cognitive development
among children.
Female partners of circumcised men do not report a lower rate of cervical cancer, 40 nor does circumcision prevent penile cancer.41 A recent study shows that the penile cancer rate is higher in the US
than in Denmark, where circumcision, except
among Middle - Eastern immigrant workers, is almost unheard of.42 Indeed, researchers should investigate the possibility that circumcision has actually
increased the rate of these diseases.
The four park proposals are
among more
than 20 questions that will be on the ballot, most of them asking for tax
increases.
The estimated percentage of US children aged 2 to 5 years and 6 to 11 years classified as overweight
increased from 5.0 % and 6.5 % in 1980 to 10.4 % and 19.6 %, respectively, in 2007 -2008.1-3 The
increase in childhood obesity was also observed
among those aged 6 to 23 months, from 7.2 % in 1980 to 11.6 % in 2000.1 Given the numerous health risks related to childhood obesity,4 - 7 its prevention is becoming a public health priority.8 It has been reported that feeding practices affect growth and body composition in the first year of life, with breastfed infants gaining less rapidly
than formula - fed infants.9 - 14 There is also evidence that breastfed infants continue to have a low risk for later childhood obesity.15 - 18
Because mean child IQ scores at age 6.5 years, verbal IQ scores in particular, were higher
among children in the intervention
than the control group, 16 we might expect that socioeconomic inequalities in child IQ would be widened in the intervention group, owing to the
increase in observed inequalities in breastfeeding.
The
increased socioeconomic inequalities in breastfeeding observed in the intervention group supports the argument that population intervention strategies could inadvertently exacerbate, rather
than mitigate, socioeconomic inequalities, particularly when the intervention aims to change individual behaviours rather
than targeting «upstream» structural changes.25 Our results are also compatible with an observational study from Brazil reporting that breastfeeding rates
increased first
among the socioeconomically better - off, followed by
increases among the poor, over a 20 - year period of active breastfeeding promotion campaigns in Brazil.26
Its Committee on Fetus and Newborn wrote Monday that less
than 1 percent of all births in the U.S. are homebirths, but that rate has been
increasing among white women in recent years.
Furthermore, the report found that
among women who had a vaginal delivery at second birth, the rate of a severe tear was 7.2 % in women with a tear at first birth, compared to 1.3 % in women without, a more
than five-fold
increase in risk.
The percentage of SIDS infants bed - sharing at the time of death
increased from 19.2 percent to 37.9 percent, especially
among infants younger
than 2 months, and the percentage found in an adult bed
increased from 23.4 percent to 45.4 percent.
Approximately 175000 cancer cases are diagnosed annually in children younger
than age 15 years worldwide, 1 with an annual
increase of around 0.9 % in incidence rate in the developed world, only partly explained by improved diagnosis and reporting.1, 2 Childhood cancer is rare and its survival rate has
increased significantly over the years owing to advancement in treatment technologies; however, it is still a leading cause of death
among children and adolescents in developed countries, ranking second
among children aged 1 to 14 years in the United States, surpassed only by accidents.1, 3 Childhood cancer is also emerging as a major cause of death in the last few years in Asia, Central and South America, Northwest Africa, and the Middle East, where death rates from preventable communicable diseases are declining.2
Controls were more likely to have ever breast fed (79 %, 95 % CI 71 — 86 %)
than infants in England and Wales in the Infant Feeding Surveys from 1995 (68 %) and 2000 (71 %), or be breast feeding at 6 months (27 %, 95 % CI 20 — 35 %)
than in the surveys from 1995 (22 %) and 2000 (22 %).2
Among the controls, the proportion ever breast fed
increased with social class of the main wage earner in the household from 57 % in social class V to 88 % in social class I.
Both studies reported some
increased risk in morbidity
among women with more
than one prior cesarean delivery, although the absolute magnitude of the difference in these risks was small (eg, 2.1 % versus 3.2 % composite major morbidity in one study)(74).
«A Dutch study of more
than 500,000 women reported that planning a home birth does not
increase the risks of perinatal mortality and severe perinatal morbidity
among low risk women provided they were supported by well trained midwives and a good transportation and referral system» (quote article 24).
Some dental malocclusions have been found more commonly
among pacifier users
than nonusers, but the differences generally disappeared after pacifier cessation.284 In its policy statement on oral habits, the American Academy of Pediatric Dentistry states that nonnutritive sucking behaviors (ie, fingers or pacifiers) are considered normal for infants and young children and that, in general, sucking habits in children to the age of 3 years are unlikely to cause any long - term problems.285 There is an approximate 1.2 - to 2-fold
increased risk of otitis media associated with pacifier use, particularly between 2 and 3 years of age.286, 287 The incidence of otitis media is generally lower in the first year of life, especially the first 6 months, when the risk of SIDS is the highest.288, — , 293 However, pacifier use, once established, may persist beyond 6 months, thus
increasing the risk of otitis media.
Infants born prematurely have an
increased risk of SIDS, 101,102 and the association between prone sleep position and SIDS
among low birth weight infants is equal to, or perhaps even stronger
than, the association
among those born at term.69 Therefore, preterm infants should be placed supine for sleep as soon as their clinical status has stabilized.
Preterm infants are at
increased risk of SIDS, 12,13 and the association between prone sleep position and SIDS
among low birth weight infants is equal to, or perhaps even stronger
than, the association
among those born at term.14 Preterm infants and other infants in the NICU should be placed in the supine position for sleep as soon as the infant is medically stable and significantly before the infant's anticipated discharge, by 32 weeks» postmenstrual age.15 NICU personnel should endorse safe - sleeping guidelines with parents of infants from the time of admission to the NICU.
The brunt of the cuts fell on lower civil service grades, with some losing over 30 per cent of staff (more
than 60,000 posts were lost
among administrative officers and assistants) while staff in top grades (Grade 7 and above) showed a small net
increase.
Among other findings, the report also revealed that while the total number of County residents on Medicaid has risen due to fuller implementation of the Affordable Care Act («ACA»), Erie County's portion of Medicaid costs is projected to drop by more than $ 6.4 million from 2013 due to the Act's implementation and the state's Medicaid cap, and is approximately $ 340,000 less than 2012; the biggest increase in Medicaid recipients was seen among whites age 18 - 64, while other demographics remained consistent; and that the number of persons on Medicaid continues to grow at an average rate of more than 4 % each year, a trend noted by the Medicaid Inspector General's office in his September 2013 re
Among other findings, the report also revealed that while the total number of County residents on Medicaid has risen due to fuller implementation of the Affordable Care Act («ACA»), Erie County's portion of Medicaid costs is projected to drop by more
than $ 6.4 million from 2013 due to the Act's implementation and the state's Medicaid cap, and is approximately $ 340,000 less
than 2012; the biggest
increase in Medicaid recipients was seen
among whites age 18 - 64, while other demographics remained consistent; and that the number of persons on Medicaid continues to grow at an average rate of more than 4 % each year, a trend noted by the Medicaid Inspector General's office in his September 2013 re
among whites age 18 - 64, while other demographics remained consistent; and that the number of persons on Medicaid continues to grow at an average rate of more
than 4 % each year, a trend noted by the Medicaid Inspector General's office in his September 2013 report.
But based on the results in the county's various municipalities, it certainly seems plausible that the results were driven by an
increase in the number of suburban voters who cast their ballots for a Democrat rather
than a surge in turnout
among the solidly blue city voters.
So a restoration of confi dence in the ability of political leaders
among business leaders has coincided with an improvement in trust by the public - albeit that the huge improvement
among business leaders in confidence for Gordon Brown has been far more pronounced
than his modest
increase in electoral support.