In mice undergoing a bone marrow transplant, ATG16L1 - deficient mice were three times more likely to die or show signs of transplant rejection
than mice with the protective action of ATG16L1 in place.
Mice bred to carry a gene variant found in a third of ALS patients have a faster disease progression and die sooner
than mice with the standard genetic model of the disease, according to Penn State College of Medicine researchers.
When Bäckhed and Gordon bred mice lacking a functional FIAF gene, the mice were more than 50 % flabbier
than mice with the gene intact.
Both groups were more susceptible to hearing loss
than mice with normal Ly49H / m157 interaction.
The mice with the bacteria from the child with kwashiorkor lost, then gained and lost again, more weight
than the mice with bacteria from the healthy twin.
Analysis of the germline sequences of all the AR V genes identified greater conservation between dog and human
than mouse with either.
Germ - free mice, for instance, have been shown to exhibit lower levels of anxiety and higher locomotion
than mice with a normal gut microbial population7 - 9.
One mouse has a revelation when he sees bats flying overhead: They're little more
than mice with wings, so who's to say a mouse can't fly?
Not exact matches
If your business has a better «onboarding» process
than your competitors, I guarantee you will have far greater word of mouth (and word of
mouse) and just as importantly, you will build much stronger relationships
with these new customers that will reduce the chances of losing them way too soon in the business relationship.
The partnership will bring the House of
Mouse back to Happy Meals more
than a decade after Disney severed ties
with the burger brand.
Sands is in a much stronger position to expand in Japan
than its rival Wynn, which is hobbled by a weaker
MICE position, a bruising legal battle
with former vice chairman Kazuo Okuda over bribery allegations in the Philippines, and the recent downfall of founder Steve Wynn.
Both TRPV1 / WT and KO
mice treated
with capsaicin and TPA together exhibited higher COX - 2 protein levels
than groups treated
with TPA alone (Fig. 2A), and tumors from TRPV1 / KO
mice expressed the highest level of COX - 2 as a result of treatment
with capsaicin and TPA together (Fig. 2A).
YES I still think wenger can nick the 4th because that his job and he is good
with but if you all want trophy
than you all have to wait for luck, see which micky
mouse cup that top club don't want.
She shows us how you can show your love for the «Happiest Place on Earth»
with more
than just a pair of Mickey
Mouse ears (not that there's anything wrong
with that)!
I worked
with the American Cancer Society in the late 1980s through the 1990s and lived through the «more 6 - year - olds can recognize Joe Camel
than Mickey
Mouse» days.
Even in the first week after an election, the Whitehall agents of the 800 lb gorilla of executive power are hard at work on the tiny but irritating squeak of the parliamentary
mouse rather
than fixing the broken democracy in partnership
with parliament, «back to normal working» is not the slogan that will restore the reputation and capability of our democracy.
We have the money to create real jobs, we have the people who need real jobs, but we have only got mickey
mouse politicians that are more concerned
with their own careers rather
than serving the interests of the nation.
However, this study revealed that
mice are more similar to humans
than previously thought,
with an average of around 10 % of active genes escaping X-inactivation per tissue.
In experiments
with mice, the researchers found that Paneth cells engineered to lack a functional ATG16L1 gene were five times more likely to die in the face of rising TNF - alpha signals
than normal cells.
For all the human -
mouse mixing, however, the rodents were no better learners
than those
with mouse - only brains.
From 2010 to 2016, the proportion of adult
mice with white fur patches more
than doubled, the team reports today in Royal Society Open Science.
The combination therapy increased the average survival to 37 days,
with four of the
mice living more
than 120 days.
Twelve transgenic piglets endowed
with a
mouse UCP1 gene were better able to maintain their body temperature
than their unmodified counterparts when they were exposed to cold for a 4 - hour period, the authors report today in the Proceedings of the National Academy of Sciences.
In a study, when
mice ate broccoli
with their regular diet, they were better able to tolerate digestive issues similar to symptoms of leaky gut and colitis
than mice that were not placed on a broccoli - supplemented diet, according to Gary Perdew, the John T. and Paige S. Smith Professor in Agricultural Sciences, Penn State.
When the researchers injected myelin - deficient regions in the
mice with a drug that prevents destruction of the AXIN2 protein, the
mice grew myelin sheaths faster
than untreated
mice, repairing the damage.
With no more
than a change in diet, laboratory agouti
mice (left) were prompted to give birth to young (right) that differed markedly in appearance and disease susceptibility.
In the study, led by post-doctoral fellow Long N. Nguyen of Duke - NUS, researchers found that
mice without the Mfsd2a transporter had brains a third smaller
than those
with the transporter, and exhibited memory and learning deficits and high levels of anxiety.
They also had less organ damage
than mice that had been injected
with doxorubicin (Proceedings of the National Academy of Sciences, DOI: 10.1073 / pnas.1004604107).
To their surprise, they found that these Th17 - deficient
mice experienced far more aggressive cancer growth
than normal
mice —
with the cancer completely smothering the lungs within 16 days.
Like the Rosetta Stone that scholars used to decode hieroglyphics, researchers trained the algorithm
with more
than 4,600 T cell receptors and then used it to correctly assign 81 percent of the human T cells and 78 percent of
mouse T cells to one of 10 different viral epitopes.
Mice with one particular extra section of the human chromosome spent significantly less time hunting for the platform in its original location than did mice carrying other chromosome porti
Mice with one particular extra section of the human chromosome spent significantly less time hunting for the platform in its original location
than did
mice carrying other chromosome porti
mice carrying other chromosome portions.
The team found that humans are equipped
with tiny differences in a particular regulator of gene activity, dubbed HARE5, that when introduced into a
mouse embryo, led to a 12 % bigger brain
than in the embryos treated
with the HARE5 sequence from chimpanzees.
The
mice treated
with rapamycin also ended up
with better quality memory T - cells
than the control
mice.
Despite the presumed virulence of the strain — experiments
with mouse lungs showed it produces 1000 times more bacteria in infected cells
than do standard varieties — Valway says the number of TB cases that developed were kept in line
with other typical outbreaks, which «shows that doing good contact investigations is important and preventative therapy works.»
Heber - Katz says another scientist working
with the
mouse model of lupus also noticed the closing ear holes, but thought of it as an inconvenience rather
than a eureka moment, saying, «These darn
mice, you have to keep going upstairs to punch holes in their ears!»
«
Mice that don't have these molecules seem to be able to change their brain circuits with experience much more rapidly than normal mice,» Shatz s
Mice that don't have these molecules seem to be able to change their brain circuits
with experience much more rapidly
than normal
mice,» Shatz s
mice,» Shatz says.
Scientists imaged more
than 1,700
mouse brains (injected
with a tracer virus) at resolutions less
than a micrometer, or 50 times smaller
than a human hair.
Three days later, bone growth was three times greater
than in
mice injected
with a placebo (Science Translational Medicine, DOI: 10.1126 / scitranslmed.3000231).
Base oxidation regulates gene activity In cooperation
with colleagues at LMU, as well as researchers based in Berlin, Basel and Utrecht, Carell and his group have now shown, for the first time, that a standard base other
than cytosine is also modified in embryonic stem cells of
mice.
The
mice with lower levels of KMO showed impairments in contextual memory and spent less time
than did a control group interacting
with an unfamiliar
mouse in a social setting.
A click on a
mouse brings up another set of bars, thinner
than the last, and he plays around
with those until he can seethem too.
Aside from a food intake in laboratory
mice that's about 40 percent fewer calories
than normal, however, it's been found that another way to activate this pathway is
with rapamycin, which appears to have a significant impact even when used late in life.
GTC stuck
with goats because they reproduce more rapidly
than cows and can yield more protein
than mice or rabbits.
15 The results so far include short - legged
mice,
mice with fewer toes
than normal, and
mice that chirp like songbirds.
These modified
mice had significantly smaller testes and lower sperm counts
than their normal counterparts — and when the group bred them
with normal females, they found that the litter size was around half normal.
When the researchers examined
mice with disrupted IL - 27 function, they found that they were more likely
than normal
mice likely to die when infected
with the virus, and that they died as a consequence of rampant lung inflammation.
Instead
mice injected
with stem cells developed a far greater number of synapses, or connections between neurons, at the damaged site
than control
mice did.
When injected
with cancer cells, animals housed there developed tumors 80 % smaller
than those in control
mice, or no tumors at all.
For example,
mice given 25HC before being infected
with Zika virus had significantly lower blood levels of the virus
than mice given a placebo.
When the researchers then administered acetylcholine to the
mice through the nebulizer, they observed that
mice with the G protein - coupled receptors reacted more vigorously
than those
with only smooth muscle reactions, and they also showed increased airway restriction compared to their counterparts without the receptor.