The rodents experienced hormone imbalances and more and bigger breast tumours, earlier in life,
than rats fed a non-GM diet, the researchers claim.
In this study, he and his research crew discovered that aflatoxin - exposed rats fed wheat gluten exhibited less cancer growth
than rats fed the same amount of casein.
The researchers found that the sugar group gained weight faster and in larger quantities
than the rats fed the sugar - free diet.
The rats fed 20 % casein through the entire experimental period had somewhat more pre-cancerous lesions
than the rats fed 5 % during the whole period, but the difference is not very dramatic.
In 1991, however, Campbell's group published a study using Fisher 344 rats showing that rats fed 4 % casein ate more and weighed less
than rats fed greater amounts of casein ranging from 8 % to 20 % (16).
Rats fed HFCS gained a lot more weight
than rats fed real sugar, even when fed the same number of calories.
Not exact matches
A 2010 study published in the Journal of Bone and Mineral Research found that blueberry -
fed rats had significantly more bone mass
than rats whose diet was not supplemented with the berries.
The
rats fed VCO had significantly less oxidative stress markers in their kidneys
than the 5HPO
fed rats, leading the researchers to conclude ``... virgin coconut oil has a potential to reduce the development of hypertension and renal injury induced by dietary heated oil, possibly via its antioxidant protective effects on the kidneys.»
In the 1930s researchers discovered that laboratory
rats fed a limited diet live about 40 % longer
than normal and are resistant to many chronic illnesses typical of aging.
At the end of the 16 weeks,
rats on the cycled diet were 18 % heavier
than those on the healthy diet, while leptin and insulin levels in cycled
rats were in between
rats fed junk or healthy food.
Heras
fed rats an ovorubin - enriched diet and found that they grew more slowly
than normal (PLoS One, DOI: 10.1371 / journal.pone.0015059).
Barnes and his colleagues showed four years ago that female
rats fed soya bean products and dosed with cancer - causing chemicals were much less likely to develop breast cancer
than those eating proprietary
rat food.
Kolb then autopsied the
rats» brains: The formula -
fed rats had bigger brains
than the chow -
fed rats.
Other studies had showed that
rats fed fewer calories
than their slow and balding brethren maintained their shiny coats and a youthful vigour.
Some studies have found an increased cancer risk in mice and
rats who were
fed acrylamide, but those studies used doses between 1,000 and 10,000 times higher
than levels that people would be exposed to in food.
Originally, Silverman and Baumann planned to use only male
rats in their pilot studies because the cost of including both sexes would be substantial; housing and
feeding a single adult
rat runs to more
than a dollar a day.
The researchers found that the ketone ester -
fed rats ran farther and completed the maze faster and more accurately
than rats on the carb or fat diets.
In the paper, Séralini reports that
rats fed Monsanto's herbicide - resistant maize variety NK603 for 2 years — which is close to their maximum life span — died earlier
than rats on a non-GM maize diet.
In work that confirmed earlier research by others, Ross presented compelling evidence showing that
rats fed restricted diets not only lived longer
than their fully nourished counterparts but also suffered from fewer diseases.
Liang thinks
rats make better models of human
feeding behaviors
than mice because
rats are bigger mammals and eat significantly more
than mice, making it easier to measure their food intake.
However, the CD
fed rats gained weight, were insulin resistant and had higher plasma lipids
than the MCD group (25).
When both CD and MCD diets were
fed to
rats for 7 weeks, the MCD diet group had higher scores of liver inflammation and steatosis
than the CD group.
A 2008 study found that
rats fed a diet of yoghurt mixed with artificial sweetener saccharin actually gained more weight
than rats given the same amount of yoghurt mixed with glucose.
Research at the University of New South Wales suggests that high - sugar diets can lead to memory loss — in fact
rats fed a high sugar diet suffered deterioration in memory and spatial recognition in less
than one week.
Nitrosamines, which are potent carcinogens, are often found in soy protein foods, and are greatly increased during the high temperature drying process.20 Not surprisingly, animal
feeding studies show a lower weight gain for
rats on soy formula
than those on whole milk, high - lactose formula.21 Similar results have been observed in children on macrobiotic diets which include the use of soy milk and large amounts of whole grains.
In the first test, with 24 hour deprivation and chow
feeding, the
rats which had gone through restricted cycles of
feeding (on both normal and sweet food) ate 10 % more food
than the control
rats.
In the second test, with 24 hour deprivation and cookie
feeding,
rats that had been in sweet restricted cycles ate almost 20 % more food
than the control group.
This would also explain the case of weanling
rats successfully blocking aflatoxin initiation
fed 20 % protein, they were being
fed an adequate amount of protein for their age, and hence were better at fighting off disease
than their protein - starved counterparts.
Researchers from the University of Alabama at Birmingham found that obese
rats fed a high - fat, low - carb diet — comparable to what many humans consume — had more damaging and deadly heart attacks
than obese
rats fed a low - fat diet.
In the third test, in simple spontaneous
feeding without a 24 hour deprivation window,
rats conditioned by sweet foods ate more
than rats on normal chow, regardless of whether they had been restricted or not.
Interestingly enough, the
rats that had been conditioned on sweet food were not all that interested in the chow
feeding, and actually ate 20 % less chow
than the control group.
We know that the lemony aura of limonene is more
than just a scent, as it can be found in our blood after exposure.8 Furthermore, several anticancer cellular pathways appear to be affected by the terpene limonene, leading some to suggest it has anticancer, or chemopreventative, benefits.9 While
feeding it to
rats in studies has revealed some efficacy against breast tumors, 10 we have a ways to go before we can make such bold claims in humans.
Incidentally, the laboratory
rats did NOT develop similar tumors when researchers
fed them more
than 10 % of their total calories from soy protein.
When soy protein isolate was
fed to
rats, the animals required higher
than normal levels of vitamins E, K, D and B12 and developed deficiency symptoms of calcium, magnesium, zinc and many other minerals.
In 1990, researchers demonstrated that
feeding 20 % corn oil diets to
rats produced more prostaglandin E2
than feeding them diets containing 19 % coconut oil and 1 % corn oil.13
One might surmise that the
rats» metabolic mechanisms were able to detect oxidative damage to the fats, and therefore rejected them, prefering to do without rather
than to risk the consequences of
feeding their pups oxidized fats.
While Campbell's earlier scientific papers present a clear picture of protein deficiency in
rats fed 5 % casein, we get no sense from reading The China Study that these
rats had anything other
than perfect health.
Research on
rats showed a doubling of cancer cells in mice that were
fed with yogurt is more constrained
than mice without the yogurt.
Being a bit of gym
rat, I'm a bit wary of not
feeding for any longer
than 12 hours at a strech.
The pilot study, conducted by Dr. Keiko Abe of the University of Tokyo's Graduate School of Agricultural and Life Sciences, showed that healthy laboratory
rats fed a diet in which some of the carbohydrate was replaced with pure maple syrup from Canada, yielded significantly better results in liver function tests
than the control groups
fed a diet with a syrup mix containing a similar sugar content as maple syrup.
Fasting plasma glucose and insulin concentrations were reduced to control concentrations, and plasma insulin concentrations during the OGTT were significantly lower
than those in the the
rats fed fructose only at all time - points.
Similar fructose increases have been reported in healthy volunteers who consumed fructose loads between 0.5 and 0.75 g / kg34 and in individuals who consumed fructose - sweetened beverages with mixed meals.35 Leptin and ghrelin levels were indistinguishable following acute ingestion of glucose or fructose, a finding possibly attributable to the short time interval of observation; leptin levels typically change 4 to 6 hours after glucose administration.36 Although fructose was previously reported to be less effective
than glucose in suppressing ghrelin, such differences may be attributable to the different conditions and timing of ghrelin measurements.10 Little is known about the acute PYY response to fructose ingestion compared with glucose ingestion, although 1 study in
rats found higher rather
than lower PYY levels after 24 hours of glucose but not fructose
feeding.11 Whether such disparities are related to study design or species differences remains uncertain.
And now there's more evidence that diet drinks are as bad as normal ones; one university study found that
rats fed artificially sweetened drinks for ten days gained more weight
than those
fed sugar - sweetened drinks.
Finally, all concentrations were higher in
rats fed the pulse diet
than in
rats fed the spread diet.
In September 2012, Food & Chemical Toxicology published a peer - reviewed study purporting to show that
rats fed genetically modified corn had a higher incidence of tumors
than those that were not.