Gottfried's most common defense of his legislation included mentioning that its provisions were «much tighter»
than the regulations surrounding the «deadliest» and most «freely available» drugs, such as hydrocodone and oxycodone.
Such risks and uncertainties include, but are not limited to: our ability to achieve our financial, strategic and operational plans or initiatives; our ability to predict and manage medical costs and price effectively and develop and maintain good relationships with physicians, hospitals and other health care providers; the impact of modifications to our operations and processes; our ability to identify potential strategic acquisitions or transactions and realize the expected benefits of such transactions, including with respect to the Merger; the substantial level of government
regulation over our business and the potential effects of new laws or
regulations or changes in existing laws or
regulations; the outcome of litigation, regulatory audits, investigations, actions and / or guaranty fund assessments; uncertainties
surrounding participation in government - sponsored programs such as Medicare; the effectiveness and security of our information technology and other business systems; unfavorable industry, economic or political conditions, including foreign currency movements; acts of war, terrorism, natural disasters or pandemics; our ability to obtain shareholder or regulatory approvals required for the Merger or the requirement to accept conditions that could reduce the anticipated benefits of the Merger as a condition to obtaining regulatory approvals; a longer time
than anticipated to consummate the proposed Merger; problems regarding the successful integration of the businesses of Express Scripts and Cigna; unexpected costs regarding the proposed Merger; diversion of management's attention from ongoing business operations and opportunities during the pendency of the Merger; potential litigation associated with the proposed Merger; the ability to retain key personnel; the availability of financing, including relating to the proposed Merger; effects on the businesses as a result of uncertainty
surrounding the proposed Merger; as well as more specific risks and uncertainties discussed in our most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.cigna.com as well as on Express Scripts» most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.express-scripts.com.
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than one hundred vitamin B6 - dependent enzymes have been identified, mostly involved in amino acid metabolism: for oxygen transport via hemoglobin synthesis; in blood sugar
regulation via conversion of stored carbohydrate to energy; in the development of the myelin sheath
surrounding nerve cells; in the conversion of alphalinoleic acid to the essential long - chain fatty acid DHA; 28 and in the synthesis of neurotransmitters, phospholipids and sphingolipids, the vitamin niacin from tryptophan, and other vital metabolites.5 In addition to its role in enzyme reactions, B6 appears to moderate the action of some steroid hormones such as the glucocorticoid hormones, which in turn influence the metabolism of protein, carbohydrate and lipids.5, 9 B6 also is a potent antioxidant, rivaling carotenoids and vitamin E in its ability to quench reactive oxidants in the body.29
This may seem like an odd exclusion but, because private plan
regulation is monitored a lot less
than commercial airlines, insurance companies are very cautious when it comes to private planes and circumstances
surrounding crashes.