Sentences with phrase «than those in control mice»

When injected with cancer cells, animals housed there developed tumors 80 % smaller than those in control mice, or no tumors at all.

Not exact matches

The mice with lower levels of KMO showed impairments in contextual memory and spent less time than did a control group interacting with an unfamiliar mouse in a social setting.

The researchers found that wounds exposed to vibration five times a week for 30 minutes healed more quickly than wounds in mice of a control group.

In mating experiments, yogurt - eating males inseminated their partners faster and produced more offspring than control mice.

Infusing the mice with massive numbers of these plasmids under high pressure left the animals with up to 92 % less hepatitis B RNA than control animals, the researchers report in the 12 May issue of Nature Biotechnology.

Mice treated with antisense RNA (bottom) produced more dystrophin — colored red in this image — than did control mice (tMice treated with antisense RNA (bottom) produced more dystrophin — colored red in this image — than did control mice (tmice (top).

In a mouse model of triple - negative breast cancer, mice injected with cancer cells that over-express ZMYND11 had tumor volumes of less than 50 cubic millimeters while control mice and those injected with cells expressing ZMYND11 deficient for binding to the methyl group had tumor volumes ranging from 150 to 400 cubic millimeters at eight weeks.

The vaccine slowed the progression of prion disease in the remaining 70 % of the experimental mice, allowing them to live longer than control mice, which did not receive the vaccine and died within about 200 days following infection.

Several years ago, while creating a genetically engineered mouse that expresses high levels of the mouse HMGA1 gene to investigate its role in leukemia, Resar and her colleagues made the chance finding that the intestines of these animals were much larger and heavier than those of «wild - type» animals (or control mice that were not genetically modified).

However, the young mice given THC performed worse in some tests than the controls.

The analysis found the mice that were exposed to BPA had a significant decrease in beta cell mass and lower levels of insulin secretion than the control animals.

lost less weight, had fewer bacteria in their brains, and lived up to roughly 30 hours longer than the control mice

The fact that the NPY - deficient mice were no more sensitive than controls to more forceful forms of touch and painful stimuli, or even to chemicals that evoke itchiness, suggests light touch uses its own pathway in the nervous system to evoke scratching.

After 7 weeks, the group of mice on antibiotics had significantly more fat than a control group drinking plain water, the team reports online today in Nature.

In a mouse brain, the CAQK peptide binds to injured sites more effectively than the control.

Control mice, for example, spent more time sniffing around a new item placed in their cages than investigating familiar objects — a sign that their ability to react to novelty was intact.

Spinal cord neuropathology showed higher pathology scores in demyelination, meningitis, perivascular cuffing (inflammation), and overall pathology in mice that had been given resveratrol during the early phase compared with mice fed a control diet, whereas mice treated with resveratrol during the entire treatment period had significantly higher pathology scores in meningitis and overall pathology than controls.

The mice that received dengue or West Nile antibodies also had higher levels of Zika virus in their testes and spinal cords than control animals did.

They found that in control mice, activity in this region spikes higher when the mice interact with an unfamiliar mouse than with an object.

Fetuses from zinc - deficient mice in the study were 38 percent smaller on average than those from the control group fed a diet with zinc included.

In the acute model, the Cd14 - deficient mice showed greater weight reduction and intestinal barrier disruption than controls, including more severe intestinal lesions and ulcerations.

Surprisingly, while neither form of chemotherapy had any effect on the growth of these seeded metastases, Angiopoietin - 2 antibody treated mice had significantly less metastases in the lungs and in the bone and survived longer than untreated control mice.

The pups grew more slowly than those in a control group containing mother mice that drank arsenic - free water.

Cortical bone — one of the two types of bone tissue — was stronger in the treated mice than the controls, the researchers report online today in the Proceedings of the National Academy of Sciences.

Specifically, rod - mediated inner retinal responses to dim light flashes were faster in diseased mice than in their wild - type controls.

«The cells are bigger and fire less than control cells — exactly what we see in the mouse model.»

Four weeks after transplanting these cells into the kidney cavities of mice with a form of kidney anaemia, the treated animals had blood EPO levels 20 times higher than those in controls (Science Translational Medicine, doi.org/cdmx).

The brains of the mice were smaller than normal and had fewer neurons in areas that controlled the affected behaviors.

A final experiment showed that ebselen boosted SUMOylation in the brains of healthy mice more than a control injection.

In addition, the pancreases of the mice receiving ISO - 1 showed much less β - cell destruction than the control group, the team reports online this month in the journal EndocrinologIn addition, the pancreases of the mice receiving ISO - 1 showed much less β - cell destruction than the control group, the team reports online this month in the journal Endocrinologin the journal Endocrinology.

Sagawa and colleagues compared mice whose mothers had received 30 % fewer calories during pregnancy with normal controls and found that the underweight pups experienced a shift in timing: the normal increase in blood leptin a week earlier than usual.

Last, spontaneous cage activity was more than 6-fold greater in IL - 15Rα — KO mice compared with B6129 control mice, and this amount of cage running activity was greater than that noted in other mouse models, including the HIF - 1α — KO mouse (45) and mice treated with PPAR agonists (46).

Our findings are in agreement with a recently published study by Oskarsson et al. (2015) in which Tg mice injected through the tail vein with in vitro — generated aggregates from synthetic peptides containing the sequence of IAPP developed a higher percentage of IAPP aggregates in the pancreas than did untreated controls when subjected to a high - fat diet.

In the present studies, the effects of musculoskeletal loading on serum osteocalcin in db / db mice were correlated with improvements in glycemic control and insulin sensitivity, but it is important to note that total, rather than undercarboxylated, osteocalcin was measured herIn the present studies, the effects of musculoskeletal loading on serum osteocalcin in db / db mice were correlated with improvements in glycemic control and insulin sensitivity, but it is important to note that total, rather than undercarboxylated, osteocalcin was measured herin db / db mice were correlated with improvements in glycemic control and insulin sensitivity, but it is important to note that total, rather than undercarboxylated, osteocalcin was measured herin glycemic control and insulin sensitivity, but it is important to note that total, rather than undercarboxylated, osteocalcin was measured here.

Once they had achieved this precise control over the cellular interactions in the brain, they turned to exploring behavior: Mice that are less fearful are more likely to venture farther than others.

IL - 15Rα — KO mice weighed almost 20 % less than B6129 control mice, and this was reflected in the lower absolute weights of individual skeletal muscles.

The extent of IAPP amyloid deposition in Tg / Tg mice was, at all time points, significantly higher than the staining observed in Tg - hIAPP animals inoculated with control pancreas homogenate (Fig. 3 F).

In addition, this is not the only case in which the regulatory circuits that control early embryonic development in humans show greater similarity to those employed in bovine embryos than to those that operate in the mouse systeIn addition, this is not the only case in which the regulatory circuits that control early embryonic development in humans show greater similarity to those employed in bovine embryos than to those that operate in the mouse systein which the regulatory circuits that control early embryonic development in humans show greater similarity to those employed in bovine embryos than to those that operate in the mouse systein humans show greater similarity to those employed in bovine embryos than to those that operate in the mouse systein bovine embryos than to those that operate in the mouse systein the mouse system.

EDL muscle from IL - 15Rα — KO mice displayed an increase in fatigue resistance greater than control EDL muscles, although this was not a full transition to a slow phenotype.

Results showing C. minuta has an effect of controlling fat gain in the mouse match data that reveal lean people have a greater abundance of C. minuta in their gut than obese people.

The lab mice in the study that had Type I diabetes demonstrated an impressive level of control over their blood sugar for more than two days following the injection of the newly developed insulin / glucosamine compound.

The antibiotic - treated mice also showed more than a two-fold decrease in Aß plaques compared to controls, and a significant elevation in the inflammatory state of microglia in the brain.

The insulin - receptor knockout mice developed cholesterol plaques that were more than twice the size of those found in the control animals.

In an operant test R6 / 2 transgenic mice (240 - CAG repeats, B6 congenic background) were less able to acquire lever pressing than control animals at an age where motor function is only mildly affected (from 9 weeks), with this deficit being both more pronounced and detected earlier (from 5 weeks) where reinforcement was not solely contingent on responding.

The scopolamine - treated mice spent significantly less time freezing than saline controls in response to the context indicating they did not remember the environmental context (Figure 4C).

Finally, the authors assessed motor neuron counts, finding that mice receiving MSCs lost significantly fewer motor neurons than the vehicle control group, with less microglial activation and astrocytosis in the spinal cord.

Results showed the first two groups didn't develop PCOS, unlike the mice in the control group, whereas the test subjects with ovary ARs still contracted the disease, albeit at a lower rate than the normal mice.

Although body weight was not different, liver weights were significantly higher (P < 0.01) in 15 - mo - old mice derived from IVC in the presence of FCS than in control animals (Supplemental Table S2); this phenotype was transmitted to F1 and F2 males derived from F0 IVC males but was not transmitted to F1 females.

ELISPOTS in tolerant animals were similar to those from control mice (p > 0.05) but significantly lower than those in sensitized mice, p < 0.05 (Figure 7h).

Hypercholesterolemia - prone mice that were engrafted with bone marrow obtained from homozygous or heterozygous Tet2 knockout mice had larger atherosclerotic lesions in the aortic root and aorta than did mice that had received control bone marrow.