Sentences with phrase «then coaxed»

But researchers did know the genetic mutation that induced it, so Capecchi inserted that mutation into the embryonic stem cells of mice, then coaxed those cells into becoming embryos.

They then coaxed the cells to develop into early - stage neurons.

They then coaxed these induced pluripotent stem cells, which are genetically identical to the patients» cells, to develop into two separate groups of nerve cells: neurons and what are called astroglial cells.

To study the underlying cause of bipolar disorder, Gage and his colleagues collected skin cells from six bipolar patients, reprogrammed the cells to become stem cells, and then coaxed the stem cells to develop into neurons.

They allowed cells from each line to mature and then coaxed these cells to transform into iPS cells.

Zheng, together with Leah Boyer, then a researcher in Gage's lab and now director of Salk's Stem Cell Core, generated diseased neurons by taking skin cells from patients with Leigh syndrome, reprogramming them into stem cells in culture and then coaxing them to develop into brain cells in a dish.

The researchers report they were able to transform about one in 5,000 cells — enough to get several iPS cells from a single culture dish — and then coax them to become nerve cells or heart tissue on the benchtop.

Thus, in principle, a successful vaccine has to stimulate the first B cells in this lineage and then coax them along a fairly narrow evolutionary path until they have changed enough to provide effective protection against HIV.

In Europe you have to persuade many smaller funders, all of whom have different procedures, priorities, budget cycles, and even languages, and then coax them to work together.

The scientists wait a bit, then coax the mosquitoes to spit, and examine that saliva for the amount of Zika virus particles it contains.

We then coax a cell line made from an embryonic kidney into taking up the Trojan horse plasmid.

Post's team at Maastricht University in the Netherlands then coaxes them into multiplying to form small strips of muscle tissue.

The regenerative tooth fillings stimulate the stem cells, which then coax dentin growth.

In one, the dog had to herd three sheep around two cones at opposite ends of an enclosed pen and then coax them through a small opening in a gate.

It's extremely fun to meet and chat with the folks curious about her game, then coax them to give the discrete show floor demo a try.

Wait for the T - Rex to approach on its patrol, then coax it to smash through the rock.

Not exact matches

The way I feel, when someone coaxes you into starting a food blog, then you must be a great cook!

You could coax the maximum flavor out of them with seasoning, by toasting the rice, by cooking them with a tiny amount of onion and garlic in olive oil then slowly in the oven.

Let dashi sit 20 minutes (this will coax more flavor from aromatics), then fish out and discard scallions, mushrooms, ginger, and garlic.

Then I hooked a larger fish on a lightly weighted Muddler and within an asthmatic half hour of coaxing I beached it.

It's hardest on mid-majors, especially when it comes to trying to coax power - conference teams onto campus, and then smaller teams end up with few impressive pelts to show the March Madness committee, as NCAA snub Illinois State dealt with on Sunday.

A pioneer auto racing driver in his salad days, he coaxed a 1903, chain - driven Thomas Flyer up to the then spanking speed of 70 mph to win a Baltimore road race.

All Premier League teams have more money then they ever dreamed of, so it's going be hard to coax players away, as even with the added millions from the TV deals, Arsenal and Arsene seem to be sticking to their budget of the past 3 years

If you feel they are coaxing you into it by calling names first well then just try being the grown up one.

The hosts coaxed and cajoled, kept the ball on the ground to build some attractive attacks, then converted their best opening just before the break.

Since then things have gone sour for Adrian; he's started just 6 games this season and scored only three goals, making him a prime target for Arsene Wenger who is renowned for coaxing the best from youngsters.

Instead, she spent countless hours holding, rocking, singing and finally sleeping with her babies (and then toddlers) to coax them to sleep and to stay asleep.

I know it is hard, but you have to try nurse him just with your nipples, if your nipples are too sored then take a formula break, also listen for swallowing, if you do not listen any gulps: coax him, I was moving my nipples for him, my neck ended up super stiff, but it will be amazing when he finally learns to latch - swallow - and basically feed.

Will eat just one day want more than 4oz and then go longer in between feedings, or should I coax him to eat more each feeding?

The question then is which candidate can coax more of his supporters to the polls.

Then, in December 2009, he coaxed the Legislature to return to Albany to close a $ 2.7 billion midyear gap instead of allowing it to grow the following year.

Setton's lab exposed the hiPSCs to a variety of different growth factors and culture media to coax them into first developing markers for, and then fully forming into, notochord cells.

The SUNY scientists have harvested more than 10,000 of them, but less than one - tenth of a percent form culture growths that can then be coaxed into whole plants.

If the wheel can not be coaxed into working again, then Spirit will likely be trapped forever, Callas says.

Badylak's debut paper on ECM went to press right around the time scientists first coined the term «tissue engineering» to describe what was then considered a small but burgeoning field — the far - out - there efforts to coax cells into tissue to restore, maintain, or improve tissue function or whole organs.

The researchers then used a 3 - D cell culture system to coax their mutant and healthy hPSCs down the differentiation pathway into becoming kidney progenitor cells and finally the proximal tubule cells found in kidney nephrons.

She then followed up with a closer look at role of the Igf2 signaling pathway in coaxing quiescent hematopoietic stem cells to start dividing and maturing into multi-lineage progenitors that ultimately give rise to specialized blood cells.

Since then, researchers have been working furiously to coax stem cells into forming other organs.

Zhou's team will coax ES cells to develop into precursors to neurons, and will then inject them into the striatum, a central region of the brain implicated in the disease.

They went on to show that the cells — when moved to new conditions — could then be coaxed to develop into functional nephron - like structures both in the lab or when transplanted into animals.

After many attempts, CC was created by coaxing the nucleus of a cell from a calico cat into an enucleated egg; an electrical spark prompted the hybrid to divide, and the resulting embryo was then transferred into a surrogate mother.

By adding a combination of four key factors, a skin cell can be made into an iPSC, which can then be coaxed into forming liver, lung and brain cells in a culture dish.

To tap embryonic stem cells» therapeutic potential, researchers must learn how to coax them to become a specific type of cell that can then be transplanted into the body.

In the case of gene editing, Verma is creating induced pluripotent stem cells (iPSCs) from patients by taking, for example, skin cells of patients, coaxing them back into an early stem cell state, and then providing conditions to make those cells develop into more complex brain, lung, prostate and breast tissues.

They then experimented with varying combinations of well - known signaling molecules, including WNT, BMP and Hedgehog, as a way to coax these cells to become ever - more - specialized precursor cells.

But now it may be possible to take cells from someone with a neurological disease, for example, make them into iPS cells and then, treating them with chemicals and proteins that encourage the cells to differentiate, coax them into becoming neurons.

If cells from Parkinson's patients can be returned to their undifferentiated state, coaxed in the laboratory to become dopamine cells that then develop characteristics of the disease, he says, «we will have Parkinson's in a dish.»

The skin cells can be reprogrammed to become more like an embryo in that the cells can have the potential to develop into any cell type, and then they can be coaxed to the right cocktail of growth factors to become retinal cells.

They used six genes to coax these cells to revert to iPSCs, which could then be developed into blood cells.

Scientists then could spend less time coaxing stem cells to turn into other types of cells, at least as it relates to memory research.