Sentences with phrase «then in mouse models of the disease»
This was observed in human ovarian cancer cells grown in culture, and then in mouse models of the disease.
https://www.sciencedaily.com/ Not exact matches
The scientists then tested three new mTOR inhibitors currently under development (pp242, AZD8055 and INK128) in combination with the chemotherapies AraC, Etoposide and Cisplatin to see how they affected laboratory lines of leukemia cells and mouse models of the disease.
«We can collect cohorts of new patients and try to understand new aspects of the disease, model them in our system in the germ - free mice, and then drill down into the fine immunological details of the disease,» he explains.
A very large number of changes have been discovered in HD model mice and then subsequently observed in human HD patients, suggesting the mice are useful research tools, even if they don't really have Huntington's disease.
They will then examine other mouse models with mutations involved in cell - adhesion and extracellular matrix molecules for signs of RPE diseases.
These two drugs were then tested in mouse models of two neurodegenerative diseases — prion disease (mad cow) and frontotemporal dementia — the same mice in which GSK2606414 had looked good in 2013.