Sentences with phrase «then transplanted those cells»

The team then transplanted these cells into the kidney cavities of mice with a form of kidney anaemia.

«Our major CIRM - funded programs, aimed at engineering young stem cell - derived astrocytes to secrete GDNF, then transplanting those cells back into patients, take on even greater importance, given this aging phenomenon,» said Svendsen, the Kerry and Simone Vickar Family Foundation Distinguished Chair in Regenerative Medicine.

Not exact matches

This may entail making small holes in the bone to allow new cartilage to grow (microfracture), taking cartilage from another part of the athlete's knee and transplanting it into the defect (osteochondral autograft transfer), taking cartilage cells from the knee and then having them grown in a lab for later re-implantation (autologous chondrocyte implantation), or taking cartilage from a person who has passed away and placing it in the defect (osteochondral allograft transfer).

The transplanted genome booted up in its host cell, and then divided over and over to make billions of M. mycoides cells.

The cell into which the synthetic genome was then transplanted contained its own proteins, lipids and other molecules.

Craig Venter «s team at the J. Craig Venter Institute in Rockville, Maryland, and San Diego, California, has made a bacterial genome from smaller DNA subunits and then transplanted the whole thing into another cell.

We cloned a Mycoplasma mycoides genome as a yeast centromeric plasmid and then transplanted it into Mycoplasma capricolum to produce a viable M. mycoides cell.

Once the UCLA researchers had produced iPS cells that were free from Duchenne mutations, they differentiated the iPS cells into cardiac muscle and skeletal muscle cells and then transplanted the skeletal muscle cells into mice that had a genetic mutation in the dystrophin gene.

With this drug, we got him into remission, and then he could get a stem cell transplant.

In the initial work at the Roslin Institute, the egg cells along with their transplanted nuclei were then implanted directly into a foster mother, where they developed and, in the case of Dolly, resulted in a viable offspring.

Until then, Semler hadn't considered stem cell transplants a viable treatment for the disorder.

June 2008 was the first time a patient received a trachea transplant that made use of her own stem cells, in what was then the most advanced example of tissue engineering.

The researchers then introduced the two strains into mice transplanted with a human immune system and watched in real time as HIV spread from one CD4 + helper T cell to another.

Subsequent transplant of millions of human T - ALL cells into normal mice that were then treated with an anti-CXCR4 drug induced remission within two weeks, with diseased spleen and bone marrow tissue nearly returning to normal.

The experiment Orwig has in mind is to use gene - editing technology to fix this flaw in the sperm - forming stem cells and then transplant them back into infertile mice, thereby demonstrating a potential treatment for male infertility.

The studies, led by University College London (UCL) laryngologist Martin Birchall, would take donor larynxes or tracheas from donors, «seed» them with a patient's own stem cells, and then transplant them into the patient.

«Importantly, it demonstrates that one cell type — the corneal epithelium — could be further grown in the lab and then transplanted on to a rabbit's eye where it was functional, achieving recovered vision.

But if he were performing a stem cell transplant for a cancer patient who also happened to have AIDS, he reasoned, then why not use stem cells with the CCR5 deletion?

HSCs can be harvested from a suitable donor and then transplanted into a patient, where, after establishing themselves in the bone marrow, they can generate healthy blood cells.

To test their idea for the dry form, Amir Kashani of the University of Southern California in Los Angeles and his colleagues coated 6 by 4 - millimetre slithers of polymer with retinal pigment epithelial cells they had grown, then transplanted these into four people.

To treat hereditary blood diseases, doctors could take a sample of bone marrow cells from a patient, correct the faulty gene, and then grow healthy cells in the bioreactor and transplant them back into the patient.

They went on to show that the cells — when moved to new conditions — could then be coaxed to develop into functional nephron - like structures both in the lab or when transplanted into animals.

TOKYO — A Japanese group has generated functional human livers by creating liver precursor cells in the laboratory and then transplanting them into mice to complete the developmental process.

To investigate how zebrafish tails take shape, Thisse's team removed some of the presumed pre-tail cells from early - stage embryos, then transplanted them into the middle of another embryo.

They then transplanted progenitors of the inner ear cells into the inner ear of embryonic normal and Connexin 30 knockout mice using glass tubes with optimized tip sizes.

To tap embryonic stem cells» therapeutic potential, researchers must learn how to coax them to become a specific type of cell that can then be transplanted into the body.

These «off - the - shelf» cells could then be transplanted into people with type 1 diabetes to compensate for their inability to make the hormone themselves.

The biggest problem for transplanted stem cells, Bulte says, is that they're initially grown in a dish with ready access to oxygen, then put in the body, where levels are relatively low.

Then his team used a drug (not the test compound) to kill each mouse's liver before transplanting human liver cells into their bodies.

«One could envision expanding beta cells created from IPS cells in vitro and then transplanting them,» he says.

Then, they transplanted these cells into recipient mice and confirmed that the cells can form all of the blood cell lineages in vivo.

With our new technology, we can quickly create billions of these cells in a dish and then transplant them into damaged hearts to treat heart failure.»

You can give enzymes in the blood, but it won't cross the blood brain barrier; but if you give cells, or a transplant, then it will engraft in the brain as well and produce enzyme, or the other factors that are missing.

They then transplanted these early - stage cells into mice modified to have hyperglycemia (high glucose levels), a key indicator of diabetes.

And iPS cells may have a particular advantage: Taking a person's own skin cells, say, making them pluripotent, and then using those cells to grow whatever kind of tissue is needed could eliminate the use of debilitating immunosuppressive drugs, which are required when transplanting cells or tissue from a donor.

«The power of regenerative medicine is that it can potentially provide an unlimited source of functional, insulin - producing β - cells that can then be transplanted into the patient,» said Dr. Ding.

Collaborators at UCL then took these cells and transplanted them into rats that were blind due to having inherited dysfunctional RPE cells.

Dr. Blaser is identifying the factors that promote successful engraftment of transplanted cells in animal models, which he will then attempt to translate into improved approaches for human patients.

«The power of regenerative medicine is that it can potentially provide an unlimited source of functional, insulin - producing ß - cells that can then be transplanted into the patient,» said Dr. Ding, who is also a professor at the University of California, San Francisco (UCSF), with which Gladstone is affiliated.

They were then transplanted into mice where they developed further into insulin - producing cells, curing the mice of type 1 diabetes.

I was diagnosed with non-Hodgkin's diffuse B - cell lymphoma on Aug. 14, 2015, and since then, I have undergone three rounds of chemotherapy, 22 radiation treatments and an autologous stem cell transplant.

If successful, this may lead to therapies for humans in which a patient's stem cells will be reverted into iPSCs, then genetically repaired and transplanted back into the bone marrow of the same patient.

The Joslin researchers then transplanted these modified human diabetic cells into wounds in mice models of diabetes that also had suppressed immune systems so that they didn't reject human cells.

The researchers then transplant these progenitor cells into the hippocampi of mice that carry the apoE4 gene and model aspects of Alzheimer's disease.

His donated cells — which were not touched by chemotherapy — were then transplanted back into his body.

For that to be done successfully, a bone marrow donor match has to be found, and then chemotherapy given, before a person with the disease is ready to have donor bone marrow cells transplanted.