Sentences with phrase «therapeutic agents in»
This two - day workshop will focus on the dynamic relationship facets of training parents to be therapeutic agents in their children's lives.
http://utahplaytherapy.org/
This two - day workshop (February 22 & 23rd) will focus on the dynamic relationship facets of Dr. Landreth's 10 - session CPRT filial therapy training model, designed to train parents to be therapeutic agents in their children's lives.
Polyphenols: Multipotent Therapeutic Agents in Neurodegenerative Diseases 7.
Other studies support these findings and medium chain triglycerides are being intensively studied as potential therapeutic agents in Alzheimer's disease (30, 31).
«The result is quite significant since we showed in previous experiments that the same nanoparticles can also be used to navigate therapeutic agents in the vascular network using a clinical MRI scanner,» Martel remarked.
Another interesting aspect to the work is that it demonstrates the possibility of adding new machinery to human cells to enable them to make therapeutic agents in response to disease signals.»
«We know that 70 - 75 percent of glioblastoma patients undergo surgery for tumor debulking, and we have previously shown that MSCs encapsulated in biocompatible gels can be used as therapeutic agents in a mouse model that mimics this debulking,» he continued.
Oruc N, Ozutemiz AO, Yukselen V, Nart D, Celik HA, Yuce G, Batur Y. Infl iximab: a new therapeutic agent in acute pancreatitis?
Not exact matches
When the institute tried injecting Ebola - infected animals — first guinea pigs, then monkeys — with its therapeutic agent encased in the lipid nanoparticles, the survival rate rose to 100 %, from around 20 % in previous trials.
The leader of such a group must be highly skilled in order to help the group per se become a therapeutic agent and to minimize the following dangers: (a) Transference distortions.
It has lost this in two different ways: one is through the psychologizing of religion, whereby the church becomes basically a therapeutic agency, and the other through the politicizing of religion, whereby the church becomes an agent of change, a political institution.
Treatment of APL requires cycles of multiple therapeutic agents, including chemotherapy, in three distinct phases: induction, consolidation, and maintenance.
Breastfeeding is contraindicated in infants with classic galactosemia (galactose 1 - phosphate uridyltransferase deficiency) 103; mothers who have active untreated tuberculosis disease or are human T - cell lymphotropic virus type I — or II — positive104, 105; mothers who are receiving diagnostic or therapeutic radioactive isotopes or have had exposure to radioactive materials (for as long as there is radioactivity in the milk) 106 — 108; mothers who are receiving antimetabolites or chemotherapeutic agents or a small number of other medications until they clear the milk109, 110; mothers who are using drugs of abuse («street drugs»); and mothers who have herpes simplex lesions on a breast (infant may feed from other breast if clear of lesions).
«Thus, we hope that its potential as a powerful therapeutic agent for the treatment of autoimmune diseases will facilitate its use in future clinical trials.»
«These results provide the basis for the potential implementation of 5 - LO - inhibitors as stem cell therapeutic agents for a sustained AML cure, although this must be investigated further in preclinical and clinical studies in humans,» explains Dr. Ruthardt.
«Our study contributes to an improved understanding of how cellular metabolism plays an important role in the acquisition of resistance to certain therapeutic agents,» said Sérgio Dias.
«It is possible that perhaps a therapeutic agent targeting BACE1 in humans might have a similar effect,» he says.
Structure - based drug design, in which the physical structure of a targeted protein is used to help identify compounds that will interact with it, has already been used to generate therapeutic agents for a number of infectious and metabolic diseases.
The therapeutic system will consist of the active agent itself, of a formulation containing the active agent, a hydrogel as carrier material for the formulation, and a suitable applicator for inserting the patch in the nose.
Scientists are hopeful that ultimately these cells could be transformed in the laboratory to yield specific cell types needed for a particular treatment, or to cross the «blood - brain barrier» by expressing specific therapeutic agents that are released directly into the brain.
«It is our hope that Dr. Yin's research will lead to additional potential therapeutic agents like ZF143 to reactivate mechanisms for the repair and regeneration of damaged heart muscle tissue in humans.»
There is also a lack of effective therapeutic agents for controlling mucus overproduction in otitis media.
After a successful postdoc at the Ontario Cancer Institute, where he developed a proprietary platform for the discovery of novel cancer therapeutic agents, Bray was asked to join the former Amgen Research Institute in Toronto (now called the Advanced Medical Discovery Institute and no longer part of the parent company) as the head of their quantitative biology group and act as liaison to Amgen Inc. in California.
«Well - rested flies: Therapeutic agent reduces age - related sleep problems in fruit flies.»
«Our findings suggest that PRMT5 is a possible prognostic factor and therapeutic target for glioblastoma, and they provide a rationale for developing agents that target PRMT5 in this deadly disease,» says co-corresponding author Robert A. Baiocchi, MD, PhD, associate professor of medicine and a hematologist at the OSUCCC — James who is also collaborating on an Ohio State effort to develop a PMRT5 inhibitor.
Originally described in the 1980s, the potential of oligonucleotides as therapeutic agents spawned hundreds of clinical trials and billions of dollars of investment in companies developing these therapeutics without generating successful products.
«Exosomes were first described in the mid-1980s, but we only now are beginning to appreciate their potential as therapeutic agents.
Alpha1 - antitrypsin is already a therapeutic agent used for replacement therapy in deficient individuals suffering from respiratory disease.
In past projects, researchers in Brady's lab have mined microbes from soil in search of naturally occurring therapeutic agentIn past projects, researchers in Brady's lab have mined microbes from soil in search of naturally occurring therapeutic agentin Brady's lab have mined microbes from soil in search of naturally occurring therapeutic agentin search of naturally occurring therapeutic agents.
In addition, therapeutic agents can be developed and tested using imaging technologies that are directly translatable to the clinic.
It is our hope that the Phase 3 trial will result in the first therapeutic agent for this condition.»
Surprisingly, if TOR's activity is acutely inhibited by treatment with the therapeutic agent Rapamycin, sleep quality improves even in old flies, suggesting that age - related sleep decline is not only preventable, but also reversible.
«Our work and that of our colleagues on stress and CRF have been mechanistically implicated in Alzheimer's disease, but agents that impact CRF signaling have not been carefully tested for therapeutic efficacy or long - term safety in animal models,» said the study's principal investigator and corresponding author Robert Rissman, PhD, assistant professor in the Department of Neurosciences and Biomarker Core Director for the Alzheimer's Disease Cooperative Study (ADCS).
Dr. Dong said the findings have significant implications in the prevention and treatment of type 2 diabetes and could prove to be useful targets for modulation of insulin sensitivity and glucose homeostasis and as a target for therapeutic agents to increase liver function to prevent diabetes.
The study, called «Molecular Determinants of Drug - Specific Sensitivity for Epidermal Growth Factor Receptor (EGFR) Exon 19 and 20 Mutants in Non-Small Cell Lung Cancer,» and published online in the journal Oncotarget, demonstrates how computer modeling of EGFR mutations found in lung cancer can elucidate their molecular mechanism of action and consequently optimize the selection of therapeutic agents to treat patients.
Gad Berdugo, CEO of EpiVax Oncology, says that such therapeutic vaccines could be used in combination with checkpoint inhibitors or, potentially, as single agents.
Regardless of age, the main therapeutic classes of AI medications used in the population were cardiovascular agents such as blood pressure medications, central nervous system agents such as sleeping pills, pain medications, and muscle relaxers, metabolic agents such as medications for diabetes and cholesterol, and psychotherapeutic agents such as antidepressants and antipsychotics.»
Knowing that Notch governs vessel permeability makes it a candidate for new drugs to treat cardiovascular diseases as well, and the team is also investigating the TMD as a potential therapeutic agent itself, as cell models that were exposed to leak - inducing inflammation displayed a dramatic reduction in leakage when they were engineered to express the TMD.
Allender and former veterinary student Lauren Kane demonstrated, however, that administering treatments via a fine spray allows therapeutic levels of terbinafine, an antifungal agent that kills O. ophiodiicola in cell culture, to get into healthy snakes» blood plasma.
In a study to be published online February 2 in Nature Communications, scientists from the Icahn School of Medicine at Mount Sinai describe an extensive analysis of novel grape - derived compounds, dihydrocaffeic acid (DHCA) and malvidin - 3» - O - glucoside (Mal - gluc), which might be developed as therapeutic agents for the treatment of depressioIn a study to be published online February 2 in Nature Communications, scientists from the Icahn School of Medicine at Mount Sinai describe an extensive analysis of novel grape - derived compounds, dihydrocaffeic acid (DHCA) and malvidin - 3» - O - glucoside (Mal - gluc), which might be developed as therapeutic agents for the treatment of depressioin Nature Communications, scientists from the Icahn School of Medicine at Mount Sinai describe an extensive analysis of novel grape - derived compounds, dihydrocaffeic acid (DHCA) and malvidin - 3» - O - glucoside (Mal - gluc), which might be developed as therapeutic agents for the treatment of depression.
Skin cells reprogrammed to act like embryonic stem cells — a breakthrough first reported in human cells 2 weeks ago — are already showing promise as a therapeutic agent.
Scientists have developed a new RNA interference (RNAi) therapeutic agent that safely blocked ocular inflammation in mice, potentially making it a new treatment for human uveitis and diabetic retinopathy.
In conclusion, the antibodies characterized herein show promise for development as broadly reactive therapeutic agents against the pandemic H1N1 influenza virus, as well as against the majority of H1N1 and H5N1 influenza strains.
Hence, there is considerable interest in developing agents capable of inhibiting myostatin activity for both agricultural and human therapeutic applications.
The researchers plan to intensively study the immune responses generated by therapeutic vaccines, broadly neutralizing antibodies, and latency reversing agents in both acutely infected individuals and also in preclinical studies.
These results could pave the way for the use of progesterone against glioblastoma in a human clinical trial, perhaps in combination with standard - of - care therapeutic agents such as temozolomide.
His staff is highly motivated to disseminate their work via publications and to participate in the discovery and development of novel therapeutic agents.
The investigators noted that if the antisense approach works for ALS — by delivering therapeutic agents for neurodegenerative diseases across the highly impermeable blood - brain barrier — it would likely also work in other neurodegenerative conditions, including Alzheimer's, Parkinson's and Huntington's diseases.
Researchers are focused primarily on three ways to make a therapeutic agent out of CRISPR, in which a guide RNA directs the Cas9 enzyme to a specific location in DNA for precise editing.
In other words, Ras proteins naturally lack areas that are accessible, high - affinity binding targets for potential therapeutic agents.