Sentences with phrase «therapeutic avenue»
Therefore, identifying bioactive molecules able to target the enteric nervous system, which controls the motility of intestinal smooth muscle cells, represents a new therapeutic avenue.
https://www.molecularmetabolism.com/
Epigenetic dysregulation has been implicated in neurodegenerative disorders, while targeting histone acetylation is a promising therapeutic avenue for PD.
Non-microbicidal small molecule inhibition of polysaccharide metabolism in human gut microbes: a potential therapeutic avenue — Anthony D. Santilli — ACS Chemical Biology
«Disruption of the exosomal metabolic adaptation of cancer cells could provide a novel therapeutic avenue for exploitation,» he said.
As a consequence, modulating nucleocytoplasmic transport could become a promising and new therapeutic avenue.»
«Any compound that targets these factors opens up a new therapeutic avenue for cancer,» Pelletier notes.
This new information might also provide a new therapeutic avenue researchers could explore as a means to reduce risk of liver injury in some people.
The ecRNAs, they say, are fundamental regulators of DNA methylation patterns in the adult brain through interaction with DNA methyltransferase enzymes, and the ecRNAs may offer a promising future therapeutic avenue to treat neuropsychiatric disease states associated with changes in DNA methylation, as they report in the July 7 issue of Nature Communications.
Therefore, developing drugs that block the ability of cancer cells to disseminate is a major anti-cancer therapeutic avenue.
Two drugs recently showed promise in clinical trials, and now a study in Science Translational Medicine offers both an unprecedentedly deep explanation of how the disease progresses and introduces another potential therapeutic avenue.
«Understanding how wounds can be healed is believed to be very important and a potential therapeutic avenue for the treatment of inflammatory bowel disease,» said Dr. Tim Denning, associate professor in the Institute for Biomedical Sciences at Georgia State.
«Although this mutation only exists in a small percentage of cases, this discovery points to a potential therapeutic avenue for these patients.»
This study provides a therapeutic avenue to explore.»
«There's a lot of work needed before we want to seriously propose that this is going to be a therapeutic avenue,» says Rowitch.
But the discovery of A20's crucial regulatory role should open up new therapeutic avenues.
«Understanding the mechanisms that promote aberrant neurogenesis caused by traumatic brain injury and subsequent seizures may open new therapeutic avenues to prevent epilepsy and associated memory problems caused by impact,» said senior author Dr. Jenny Hsieh, Associate Professor of Molecular Biology and a member of the UT Southwestern Hamon Center for Regenerative Science and Medicine.
The findings provide insight into the biological pathways that may predispose an individual to disease and could ultimately lead to the development of new therapeutic avenues to treat the five major psychiatric illnesses.
Future studies aimed at whether this is a productive versus a faulty adaptive fuel shift could lead to new therapeutic avenues for heart failure.
«The findings open new therapeutic avenues, particularly for the Group 3 and 4 subtypes where patient outcomes are inferior for the majority of affected children.»
A new study led by researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) identifies potential new therapeutic avenues for patients with Alagille syndrome.
Develop and de-risk new therapeutic avenues to treat serious, complex human disease by understanding the biological mechanisms.
«The findings open new therapeutic avenues, particularly for the Group 3 and 4 subtypes, where patient outcomes are inferior for the majority of affected children,» said Paul Northcott, PhD, of St. Jude Developmental Neurobiology.
By identifying new ligands, he plans to provide new therapeutic avenues for people living with spinal cord injuries.
In all, 22 noted scientists and clinicians spoke on CDG research and future potential therapeutic avenues.
She is exploring new therapeutic avenues for the aggressive forms of this type of cancer.
These unique experimental models have been yielded mechanistic insight and potential new therapeutic avenues.
In contrast, re-introduction of neurogenesis or stimulation of neuroplasticity in the adult brain both represent promising therapeutic avenues to improve psychiatric and neurodegenerative conditions.
This overview describes how newly identified genes implicated in human neurodegenerative diseases are making their way into the easy - to - manipulate fruit fly and providing new insights into disease pathology and therapeutic avenues.
This study therefore characterizes the structural and cellular bone phenotype in a mouse model of autism that can be further utilized to investigate therapeutic avenues to treat bone fractures in children with autism.
He will present and demonstrate the foundations of treatment while detailing the elements of SPACE, which offers clinicians a number of proven, integrated therapeutic avenues and techniques.
Not exact matches
That balance has changed considerably in the past few years, as alternative avenues of stem - cell science have opened up and it increasingly seems like whatever therapeutic potential such cells may someday have could be explored and achieved without the destruction of embryos.
«Using approved therapies for one condition to treat another, or drug repurposing, offers new avenues to speed Parkinson's therapeutic development,» said Dr Brian Fiske, senior vice president of research programs at MJFF.
The continuation of this line of research is opening new avenues to identify what specific signals are used to promote this increased neurogenic response, with views focused in targeting neurogenesis as a therapeutic approach to promote the regeneration of lost neurons.»
«This in turn could present exciting new avenues for therapeutic research.»
We hope that knowledge derived from this new taxonomy will comprise an important first step in facilitating international cooperation of research, ultimately leading to new avenues for diagnosis and therapeutic intervention.»
The team is currently looking into methods to target the STAT3 - PRL - 3 pathway in AML, which could open up new avenues to treat AML patients with high expression of PRL - 3 and offer an attractive anti-leukemia therapeutic strategy.
«This finding opens a new avenue for a therapeutic strategy for this disease,» said Andrew Berglund, Ph.D., a professor of biochemistry and molecular biology in the University of Florida College of Medicine.
Before he joined Moderna in 2013, Dr. Frederick was a Translational Research group leader at Aveo Oncology, focused on the generation of biomarkers for therapeutic response prediction, as well as avenues to modulate the tumor microenvironment for therapeutic benefit.
Two recent developments involving the California Institute for Regenerative Medicine (CIRM) again serve to underscore the reality that adult and other non-embryonic avenues of stem cell research are advancing at a far more dramatic pace toward providing actual therapeutic benefits for patients than is human embryonic stem cell research (hESCR).
We believe that leveraging human intuition through creation of a scientific game for drug discovery can not only provide a new avenue to discover therapeutic drugs for protein targets, but can also contribute to the development of new sophisticated algorithms to use in computer aided drug design.
Through these studies he has identified a new transcription factor and associated pathway that could yield new avenues for therapeutic intervention in SMA.
Bromodomains have long been a target of cancer therapuetic development, and the YEATS domain may now provide a new avenue for the development of future therapeutic targets.
These studies have opened up new avenues for therapeutic intervention throughout the different stages, and have also aided in the identification of biomarkers that can help in determining disease diagnosis and prognosis.
A growing body of research indicates that eHealth tools provide therapists with avenues to enhance connection between sessions, strengthen one's understanding of therapy material, encourage self - reflection, and provide access to therapeutic support 24/7.
This avenue of research should be further pursued, as it offers a hint that the beneficial effects of this therapeutic relationship element are not restricted to face - to - face therapies.