Sentences with phrase «therapeutic drugs in»

Toxicology Neogen's line of drug detection test kits is sold worldwide for the detection of abused and therapeutic drugs in farm animals and racing animals, and for detection of drug residues in meat and meat products.

«There are no new therapeutic drugs in development,» says Manjula Lusti - Narasimhan of the WHO's Department of Reproductive Health and Research.

Not exact matches

Though hailed as «a new therapeutic principle» in 1990, it nonetheless took another eight years for the FDA to approve the first antisense drug, fomivirsen — for the treatment of AIDS - related retinitis caused by human cytomegalovirus.

There is significant preliminary research supporting the potential therapeutic value of CBD, and while it is not yet sufficient to support drug approval, it highlights the need for rigorous clinical research in this area.

If the test says «yes,» the treatment would continue on course; but if the answer is «no,» then a change in therapeutic approach (either different drugs or surgery) might be more appropriate,» said Dr. Bear.

There is hardly a better example of the desperate state of the drug problem in the UK than the stories of the young recovering addicts at Betel of Britain, a Christian therapeutic community that helps people to find healing from addiction through faith in Jesus.

The internist is equipped to treat the physiological problems and administer Antabuse; the psychologist is trained to do testing through which the alcoholic's therapeutic needs can be evaluated, and he may be trained to do research and psychotherapy; the psychiatrist, being a medical doctor like the internist, can prescribe medication, but his unique skills are in the area of individual and group therapy and their relationship to drug therapies; the social worker may be trained to help the alcoholic work through his marital and vocational problems and do group as well as individual therapy; the social worker may also work with spouses; the pastoral counselor is specially equipped by training to help the alcoholic with his «spiritual» problems as these relate to his sobriety and his interpersonal relationships; he may also be trained to do group and marital counseling; 40.

In early March, USADA presented the Pacquiao camp with a contract that allowed the testing agency to grant a retroactive therapeutic use exemption (TUE) to either fighter in the event that the fighter tested positive for a prohibited druIn early March, USADA presented the Pacquiao camp with a contract that allowed the testing agency to grant a retroactive therapeutic use exemption (TUE) to either fighter in the event that the fighter tested positive for a prohibited druin the event that the fighter tested positive for a prohibited drug.

Breastfeeding is contraindicated in infants with classic galactosemia (galactose 1 - phosphate uridyltransferase deficiency) 103; mothers who have active untreated tuberculosis disease or are human T - cell lymphotropic virus type I — or II — positive104, 105; mothers who are receiving diagnostic or therapeutic radioactive isotopes or have had exposure to radioactive materials (for as long as there is radioactivity in the milk) 106 — 108; mothers who are receiving antimetabolites or chemotherapeutic agents or a small number of other medications until they clear the milk109, 110; mothers who are using drugs of abuse («street drugs»); and mothers who have herpes simplex lesions on a breast (infant may feed from other breast if clear of lesions).

The Harrison Act did not recognize addiction as a treatable condition and therefore the therapeutic use of cocaine, heroin or morphine to such individuals was outlawed — leading the Journal of American Medicine to remark,» [the addict] is denied the medical care he urgently needs, open, above - board sources from which he formerly obtained his drug supply are closed to him, and he is driven to the underworld where he can get his drug, but of course, surreptitiously and in violation of the law.»

In addition, it has been restored for eight additional drug classes, including: anti-depressants, anti-retroviral, anti-rejection, seizure, epilepsy, endocrine, hematologic, and immunologic therapeutic.

In addition, risks associated with the usability, therapeutic efficacy and market share of medicinal substances are usually realized only in the final stages of drug developmenIn addition, risks associated with the usability, therapeutic efficacy and market share of medicinal substances are usually realized only in the final stages of drug developmenin the final stages of drug development.

New drug - delivery particles could release therapeutic molecules in the body only after they reached their targeted diseased tissues.

The finding, reported in tomorrow's issue of the Proceedings of the National Academy of Sciences, may help researchers narrow their search for a possible therapeutic drug against a condition that strikes one in 2000 male births.

Of approximately 300 staff at the Center for Therapeutic Research, only nine postdocs and students are conducting basic research; the rest work in drug discovery and development.

These «designer» peptides could one day make up a new class of therapeutic drugs that is more effective and results in fewer side effects.

Another reason that makes us interested in therapeutic herbs is the potential long - term harm of synthetic drugs.

«If nanoparticles are carrying a drug to deliver, different uptake could mean different therapeutic efficacy and other important differences, such as safety, in clinical data.»

Richard Hargreaves, executive director of imaging at Merck Research Laboratories, says, «Nuclear imaging using radiotracers gives the opportunity to put your arms around proof - of - concept very early in a drug discovery and development program by focusing the selection of doses to study on those proven to deliver enough drug to the target therapeutic sites.»

At a handful of sites across the country, after a four - decade hiatus, psychedelic research is undergoing a quiet renaissance, thanks to scientists like Charles Grob who are revisiting the powerful mind - altering drugs of the 1960s in hopes of making them part of our therapeutic arsenal.

The drug MDMA, a chemical cousin of mescaline and methamphetamine, can kindle intense euphoria or sublime serenity, creating a calming therapeutic environment in which to revisit trauma.

For now, Rashid's group has a list of candidate therapeutic drugs that they'll test in their new liver disease models, something that may still prove useful to patients.

He is also the principal U.S. investigator for a randomized trial that began late last year in Germany and is now being conducted here to test the value of nicotine as a therapeutic drug.

If, however, you are more interested in research you could become a health outcomes researcher, collecting data on therapeutic interventions for drug companies, or there is the Scientists Training Programme offered by the NHS.

From accelerating the identification and validation of novel therapeutic targets, to creating better animal models of human diseases in a shorter time frame, to reducing the number of failed products, Crispr looks set to shave millions off R&D costs and boost drug discovery, she says.

If these peptides are developed for therapeutic use, the researchers anticipate that they could be used either in stand - alone therapy or together with traditional antibiotics, which would make it more difficult for bacteria to evolve drug resistance.

In order to achieve therapeutic levels at the pathological site, physicians need to deliver large amounts of the drug that may cause adverse effects to other organs in the bodIn order to achieve therapeutic levels at the pathological site, physicians need to deliver large amounts of the drug that may cause adverse effects to other organs in the bodin the body.

«The number of protein functions that are currently targeted by drugs is incredibly small compared to the total number of protein interactions that could be targeted for therapeutic benefit,» says Geoffrey Wahl, a professor in Salk's Gene Expression Laboratory.

UT Southwestern Medical Center cancer researchers have identified a protein critical to the spread of deadly cancer cells and determined how it works, paving the way for potential use in diagnosis and eventually possible therapeutic drugs to halt or slow the spread of cancer.

The recent growth is driven, experts say, by aging populations and increased life expectancy in the developed world; combination products that couple a medical device with a drug, the device usually acting as a drug - delivery vehicle; miniaturization (via nanotechnology), making medical devices less invasive; and the use of molecular diagnostics to customize therapeutic regimens and to assess individual disease risk.

Structure - based drug design, in which the physical structure of a targeted protein is used to help identify compounds that will interact with it, has already been used to generate therapeutic agents for a number of infectious and metabolic diseases.

These new markers and tests could also be used to assist in treating drug dependence, in determining appropriate therapeutic levels of medical marijuana, and for monitoring women who want to stop using cannabinoids during pregnancy.

The work published in Cancer Cell complements previous research efforts from the CNIO Melanoma Group, which could lead to the development of novel drugs that selectively target the mechanism of cell autodigestion as a potential therapeutic strategy.

In the debate among clinics and researchers on SSRIs, it has been argued that SSRIs may lack specific therapeutic properties and that their beneficial effects observed in clinical trials, could be explained by different expectancies in the drug and placebo groupIn the debate among clinics and researchers on SSRIs, it has been argued that SSRIs may lack specific therapeutic properties and that their beneficial effects observed in clinical trials, could be explained by different expectancies in the drug and placebo groupin clinical trials, could be explained by different expectancies in the drug and placebo groupin the drug and placebo groups.

«Imaging of the joint could help evaluate the mechanism of a drug's therapeutic effect, and if a process turns out to be mediated by more than one chemoattractant, understanding the mechanism would allow the rational design of combination therapies to completely shut down critical steps in the process.»

University of Calgary researchers including Luchman, Weiss and Dr. Greg Cairncross — director of SACRI, and leader of the Terry Fox Research Institute (TFRI) «Therapeutic Targeting of Glioblastoma research program at the university — are now working with cancer researchers Dr. Warren Mason (Princess Margaret Cancer Centre in Toronto) and Dr. Lesley Seymour (Director of the NCIC Clinical Trials Group's Investigational New Drug Program), and drug manufacturer AstraZeneca, to plan a clinical trial testing a similar, but newer, drug related to AZD8055 (called AZD2014), in combination with TMZ, in patients with glioblastDrug Program), and drug manufacturer AstraZeneca, to plan a clinical trial testing a similar, but newer, drug related to AZD8055 (called AZD2014), in combination with TMZ, in patients with glioblastdrug manufacturer AstraZeneca, to plan a clinical trial testing a similar, but newer, drug related to AZD8055 (called AZD2014), in combination with TMZ, in patients with glioblastdrug related to AZD8055 (called AZD2014), in combination with TMZ, in patients with glioblastoma.

«If we can understand how the antidepressant causes adverse metabolic outcomes in the offspring than we can design therapeutic strategies to prevent the damage while allowing women who require these drugs to be treated but reduce the potential harm to the offspring.»

«Based on the variability of pharmacokinetic parameters and drug clearance, the two Vancomycin nomograms developed to predict therapeutic Vancomycin concentrations in healthy adults did not accurately estimate dosage regimens in older children regardless of weight or age, and therefore should not be used to aid empiric dosing,» said Dr. Jessica Gillon.

This drug has been tested in clinical trials for the treatment of sepsis, and these findings suggest a therapeutic potential for the drug in the treatment of CCMs, although considerable research remains to be done.

Two drugs recently showed promise in clinical trials, and now a study in Science Translational Medicine offers both an unprecedentedly deep explanation of how the disease progresses and introduces another potential therapeutic avenue.

«My big selling point is that a CRO can offer someone tons of experience analyzing the data from drugs used in a variety of therapeutic areas,» she says.

«A significant amount of work remains in the development of teixobactin as a therapeutic antibiotic for human use — we are probably around six to ten years off a drug that doctors can prescribe to patients — but this is a real step in the right direction and now opens the door for improving our in vivo analogues.»

Hence possible differences in treatment results can not be clearly attributed to the drugs or the therapeutic strategies.

The researchers hope that a therapeutic drug will be particularly useful for combating outbreaks in unvaccinated hotspots.

A 1997 editorial in the New England Journal of Medicine noted that «it is difficult to titrate the therapeutic dose of this drug, and it is not widely prescribed.

The authors conclude that recurrence of an atrial tachyarrhythmia was frequent in both groups, and that when offering ablation as a therapeutic option to patients with paroxysmal AF who have not previously received antiarrhythmic drugs, the risks and benefits need to be discussed and treatment strategy individually recommended.

Since small, early - stage cancers are the most responsive to drug treatments, screening is an important aspect of follow - up care for breast cancer patients, and early detection is critical in tailoring appropriate and effective therapeutic interventions.

Dr Ishwar Singh, a specialist in novel drug design and development from the University of Lincoln's School of Pharmacy, said: «Translating our success with these simplified synthetic versions from test tubes to real cases is a quantum jump in the development of new antibiotics, and brings us closer to realising the therapeutic potential of simplified teixobactins.

«Since 95 percent of cancer patients still get chemo, we realized we could make a major impact on cancer treatment by helping clinicians prescribe the right chemotherapy drug,» said Sourav Bandyopadhyay, PhD, a professor of bioengineering and therapeutic sciences in UCSF's Schools of Pharmacy and Medicine and senior author on the new study.

The authors urge utmost caution in the dosage of drugs targeting BACE1 in order to achieve a therapeutic window that balances both safety and efficacy.