It would be very easy for a team physician to let
therapeutic genes continue working for a few hours, days, or weeks after an officially sanctioned treatment ends.
Since then he has
continued to investigate new strategies to overcome the major hurdles to safe and effective
gene transfer, translate then into new
therapeutic strategies for genetic disease and cancer, and allowed new insights into hematopoietic stem cell function, induction of immunological tolerance and tumor angiogenesis.