«This has broad
therapeutic implications as well,» says Lindquist, who also is a professor of biology at MIT.
Not exact matches
This separation has significant potential
implications for health care,
as rapid and early detection will significantly improve
therapeutic outcomes.
«We have identified a pathway in microglia that may be targeted to ultimately slow disease progression in ALS and are exploring potential
therapeutic strategies and may have broader
implications for diseases such
as Alzheimer's and Parkinson's Disease amongst others.»
«Our findings have
implications for how to think about the earliest processes that drive cancer and telomerase
as a
therapeutic target.
Professor Fallon said: «This identification of an early stage cellular checkpoint that can act
as a break on allergic responses has important
implications for the development of new
therapeutic approaches for asthma and other allergic diseases.»
Dr. Dong said the findings have significant
implications in the prevention and treatment of type 2 diabetes and could prove to be useful targets for modulation of insulin sensitivity and glucose homeostasis and
as a target for
therapeutic agents to increase liver function to prevent diabetes.
This has important
therapeutic implications,
as surgical repair will not be able to address the cellular muscle defect in HLHS patients, noted Lo.
We suggest these observations will have
therapeutic implications for skeletal myopathies and systemic diseases such
as diabetes and obesity and for the aged population, in which reduced endurance impacts mortality and activities of daily living (57);
as well
as societal
implications in terms of altering athletic performance.
The findings, being presented
as part of a poster presentation at the Annual Meeting of the American Association for Cancer Research (AACR) being held in Philadelphia this week, could have
therapeutic implications specific to this rare form of the disease, say the authors.
Our findings provide mechanistic underpinnings for the previous
implication of Del - 1
as a candidate MS susceptibility gene and suggest that Del -1-centered
therapeutic approaches may be beneficial in neuroinflammatory and demyelinating disorders.
5) Saurabh K, Scherzer MT, Shah PP, Mims
AS, Lockwood WW, Kraft AS, Beverly LJ (2014) The PIM family of oncoproteins: small kinases with huge implications in myeloid leukemogenesis and as therapeutic target
AS, Lockwood WW, Kraft
AS, Beverly LJ (2014) The PIM family of oncoproteins: small kinases with huge implications in myeloid leukemogenesis and as therapeutic target
AS, Beverly LJ (2014) The PIM family of oncoproteins: small kinases with huge
implications in myeloid leukemogenesis and
as therapeutic target
as therapeutic targets.
More broadly, our findings about progranulin and inflammation could have
therapeutic implications for devastating neurodegenerative diseases such
as Alzheimer's, Parkinson's and MS.»
, Kraft
AS, Beverly LJ (2014) The PIM family of oncoproteins: small kinases with huge implications in myeloid leukemogenesis and as therapeutic target
AS, Beverly LJ (2014) The PIM family of oncoproteins: small kinases with huge
implications in myeloid leukemogenesis and
as therapeutic target
as therapeutic targets.
The ineluctable
implication of that finding is the subsidiary finding that her separation from the children for ten months while she was in Russia, the damage to her parental bond with the children during that time,... the need thereafter to reintroduce herself to the children
as their mother through supervised
therapeutic visitations, and the restrictions on her access to the children because of her husband's claims that she has untreated mental problems and would flee with them to Russia have all resulted from efforts by the father to alienate the children from their mother on a groundless basis.»
The touchy topic of touch:
Implications for developmental play therapy training and other play therapy modalities that use touch
as a
therapeutic intervention.