Sentences with phrase «therapeutic implications in»

In this review, dates fruits has medicinal value are summarized in terms of therapeutic implications in the various types of diseases through anti-oxidant, anti-cancerous and ant - diabetic character.

Not exact matches

The House Committee on Oversight and Government Reform's hearing featured a string of critics who rebuked Bresch for raising the price of a product with life - or - death implications, especially one that needs to be replaced almost every year and in a therapeutic space where Mylan has more than 90 % market share.
«We have identified a pathway in microglia that may be targeted to ultimately slow disease progression in ALS and are exploring potential therapeutic strategies and may have broader implications for diseases such as Alzheimer's and Parkinson's Disease amongst others.»
«The specific macromolecular complex investigated in this study has therapeutic implications not only for addiction, but also for Parkinson's disease and schizophrenia,» said Dr. Sergi Ferré, who led the team of scientists.
Adds Matt Kaeberlein, a biologist who studies aging at the University of Washington, Seattle, «The therapeutic implications are profound if this mechanism holds true in people.»
Yet, for Kaileh, the most rewarding aspect of her research has been engaging in biomedical work that could have real therapeutic implications.
Dr. Dong said the findings have significant implications in the prevention and treatment of type 2 diabetes and could prove to be useful targets for modulation of insulin sensitivity and glucose homeostasis and as a target for therapeutic agents to increase liver function to prevent diabetes.
This has important therapeutic implications, as surgical repair will not be able to address the cellular muscle defect in HLHS patients, noted Lo.
«Next, we will explore the therapeutic implications of our discovery by repurposing available drugs that block these adenosine receptors and are well tolerated in humans.»
Dr Jaberzadeh said the technique had exciting implications for a whole host of conditions in which «enhancement of the brain excitability» has a therapeutic effect.
Many stem cell scientists who believe the ruling will discourage investment in the therapeutic applications of ES cell research reacted with dismay to the ruling, but the ultimate implications are far from clear.
These findings may also have important implications both for the way we understand learning mechanisms and for therapeutic possibilities, in particular for rehabilitation following a stroke or in neurodegenerative disorders.
«Since neurotrophins and their receptors control the communication between the brain and peripheral organs, they could be new therapeutic targets with implications in both metabolic and neurologic diseases.»
«This concept has significant therapeutic implications and will drive the development of new therapies because it implies that MS will produce significant disability if suffered for enough time in all patients,» says co-author Dr. Pablo Villoslada, Head of the IDIBAPS research group in Pathogenesis and new treatments in multiple sclerosis and coordinator of the study.
We suggest these observations will have therapeutic implications for skeletal myopathies and systemic diseases such as diabetes and obesity and for the aged population, in which reduced endurance impacts mortality and activities of daily living (57); as well as societal implications in terms of altering athletic performance.
The findings, being presented as part of a poster presentation at the Annual Meeting of the American Association for Cancer Research (AACR) being held in Philadelphia this week, could have therapeutic implications specific to this rare form of the disease, say the authors.
With potential therapeutic implications, Stainier and a colleague also recently discovered that endothelial cells, which line the blood vessels, play a critical role in inducing the development, or proper differentiation, of red blood cells, the transporters of oxygen.
Azevedo - Pereira JM, Santos - Costa Q. [Chemokine receptors and its importance in the replication cycle of human immunodeficiency virus: clinical and therapeutic implications].
The understanding of cell identity, heterogeneity and plasticity in neuroblastoma has strong implications with respect to the development of new therapeutic strategies to eradicate tumor cells in neuroblastoma patients.
Dose and temporal pattern of estrogen exposure determines neuroprotective outcome in hippocampal neurons: therapeutic implications.
The results of the present study have shed unexpected light into the mechanisms of vascular Ang / Tie signalling that may help to answer a number of enigmatic questions in the Ang / Tie field and that may have implications for the therapeutic exploitation of Ang - Tie signalling, particularly in the context of tumour angiogenesis.
And what are the therapeutic implications of such findings in aging people not exposed to this neurotoxin?
Our findings open the way to develop therapeutic strategies to remove lipofuscin from RPE cells, which may have implications for the treatment of age - related macular degeneration in which lipofuscin accumulation in cells is a causative factor.
Even if glcosepane's low tissue burden in rats means that cleaving it will not have dramatic rejuvenating effects in these animals (which is a reasonable prediction, but might be happily disproven in the event), its high prevalence in aging and diabetic human collagen, and its implication in the complications of diabetes, will make the mere demonstration of a candidate's ability to cleave glucosepane crosslinks in vivo a sufficient proof - of - concept to spur further work to move it down the therapeutic pipeline into human testing.
We still do not know whether certain DNA variations can result in the assembling and perpetuation of specific microbiota profiles, and this may bear important implications for the potential to treat common diseases through therapeutic modification of the gut flora.»
Our findings provide mechanistic underpinnings for the previous implication of Del - 1 as a candidate MS susceptibility gene and suggest that Del -1-centered therapeutic approaches may be beneficial in neuroinflammatory and demyelinating disorders.
Diverse cellular functions and therapeutic implications of Poly (ADP - ribose) family members: promising targets in cancer therapy
5) Saurabh K, Scherzer MT, Shah PP, Mims AS, Lockwood WW, Kraft AS, Beverly LJ (2014) The PIM family of oncoproteins: small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets.
, Kraft AS, Beverly LJ (2014) The PIM family of oncoproteins: small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets.
Pal L, Berry A, Coraluzzi L, Kustan E, Danton C, Shaw J, Taylor H Therapeutic Implications of vitamin D and calcium in overweight women with polycystic ovary syndrome..
Vitamin D deficiency is highly prevalent in patients with IBS and these results seem to have therapeutic implications >
The decline of androgen levels in elderly men and its clinical and therapeutic implications.
The therapeutic implications of ketone bodies: the effects of ketone bodies in pathological conditions: ketosis, ketogenic diet, redox states, insulin resistance, and mitochondrial metabolism
The therapeutic implications of ketone bodies: The effects of ketone bodies in pathological conditions: ketosis, ketogenic diet, redox states, insulin resistance, and mitochondrial metabolism.
In addition, the book maps out the therapeutic process, complete with implications for treatment and skills training exercises for the reader.
Relationship factors and therapy While current outcome research indicates that therapeutic relationship factors account for 30 % of client change in talk therapies, the implication is that these relationship factors are operative in relationships outside of talk therapy sessions.
Transference and countertransference in conjoint couple therapy: Therapeutic and theoretical implications: The Canadian Journal of Psychiatry / La Revue canadienne de psychiatrie Vol 27 (2) Mar 1982, 92 - 97.
Interactions between serotonin and dopamine in the control of impulsive choice in rats: Therapeutic implications for impulse control disorders
Promoting successful close interpersonal relationships in adolescence: Implications of attachment theory and research for therapeutic interventions - Markiewicz
Theoretically driven empirical studies of hypotheses that have implications for understanding and improving groups in organizational, educational, and therapeutic settings are particularly encouraged.
The ineluctable implication of that finding is the subsidiary finding that her separation from the children for ten months while she was in Russia, the damage to her parental bond with the children during that time,... the need thereafter to reintroduce herself to the children as their mother through supervised therapeutic visitations, and the restrictions on her access to the children because of her husband's claims that she has untreated mental problems and would flee with them to Russia have all resulted from efforts by the father to alienate the children from their mother on a groundless basis.»
The workshop will, in an interactive context, explore the therapeutic implications of the plenary.
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