Our group is specifically working on improvement of islet isolation and transplantation protocols in clinical practice and the development of novel
therapeutic options in the field of beta cell replacement with a clear translational «bench to bedside» approach by linking experimental research with preclinical and clinical work:
«Our study on the TACC3 - chTOG interaction will allow cellular biologists and researchers on microtubule dynamics to better understand how microtubule assembly is regulated during cellular division,» says Montoya, and he anticipates that «it could also help in developing new anti-microtubule drugs, providing more effective
therapeutic options in cancer treatment.»
This opens the door to new
therapeutic options in the treatment of breast cancer, report the researchers in the scientific journal Science Translational Medicine.
Should your child need tests we offer a full range of diagnostic and
therapeutic options in our state - of - the - art gastroenterology procedure unit.
The case is the first of its kind to report the potential effects of lenalidomide as
a therapeutic option in patients with pulmonary sarcoidosis.
The authors conclude that mesenchymal stem cell therapy has great potential as
a therapeutic option in feline disease, but that many questions about the logistics of its use remain to be answered.
They have also done a pilot study on psilocybin as
a therapeutic option in individuals with treatment - resistant depression, and are interested in possible roles for psychedelics in combating mental illnesses or addiction.
Although far more work needs to be done before bringing it to the clinic, targeting CD146 with AA98, especially in combination with an anti-TNF-alpha antibody, may be
a therapeutic option in treating colitis, as well as a preventative method for CAC.»
«This mind - body approach may be considered
a therapeutic option in the multidisciplinary management of fibromyalgia,» Wang's team said in a journal news release.
But there was nothing that a regular person could go to their bookstore and buy a book that discussed fasting as
a therapeutic option in a serious manner.
Several registered clinical trials are going to investigate the case for a KD as a supportive
therapeutic option in oncology.
Not exact matches
NovoCure (NVCR)- Optune is a revolutionary
therapeutic option with blockbuster potential
in GBM alone, the launch is going quite well, cash burn is decreasing, and data
in additional indications (such as mesothelioma) could drive additional upside.
Among all the
therapeutic options for dry eye disease, artificial tears are still the mainstay
in the initial management of a dry eye patient.
If your child has special needs, chances are you've spent an unreasonable amount of time agonizing over whether you somehow caused her problems, whether you've chosen the right medical or
therapeutic options, whether you're doing enough (or too much) to improve her chances
in life.
So, many of these parents turn to
options like boot camps,
therapeutic boarding schools, and youth detention centers
in more extreme cases.
The continuing growth
in the science of
therapeutic modalities has resulted
in a smorgasbord of modality treatment
options.
If you have decided that a
therapeutic boarding school
in South Carolina is best
option for your troubled teen son, we can help you find the solution that will be most effective for him.
While the
therapeutic boarding schools
in Georgia are a good place to begin researching, there are also a variety of
options available further from home that might be a healthier fit.
Therapeutic boarding schools are a year round
option that allows patients to get the individualized attention they need, not only
in therapy but also as students.
Although you are likely to begin your research process with
therapeutic boarding schools
in Connecticut, we want to encourage you to explore all of your
options.
«My team at Nationwide Children's has worked with commitment and dedication to develop a therapy that may subsequently be shown through future clinical trials to potentially alter the course of this unforgiving condition and provide a
therapeutic option for the families and infants with SMA1,» says Jerry Mendell, MD, principal investigator
in the Center for Gene Therapy at Nationwide Children's.
«While this strategy is very promising for a disease with few
therapeutic options, it's crucially important to keep
in mind that these tumors are located
in precarious neuroanatomical sites that just do not tolerate much swelling — and those regions are already expanded by tumors,» Monje said.
According to Qi, the interfering peptide developed
in the study «suggests a potential
therapeutic option for treatment of Huntington's disease, a disease with no treatment available.»
Because the researchers found that CTLA4Ig was effective
in suppressing hepatitis
in this study, they suggest that CTLA4Ig should be among the
therapeutic options investigated further as a potential therapy for patients with severe acute hepatitis B. To this end, this animal model is useful for virological and immunological analysis of HBV infection.
«Our study is a nice example of how the understanding of a disease on the molecular and cellular level results
in new
therapeutic options.
Research teams focused on both cutaneous and uveal melanoma are fast - tracking discoveries into the clinical setting, and bringing novel
therapeutic options to patients
in the Philadelphia region,» said Karen Knudsen, Director of the Sidney Kimmel Cancer Center.
«This study opens the door for combination therapy with BRAF inhibitors and autophagy inhibitors, which haven't been explored deeply as a
therapeutic option for patients whose tumors are resistant,» said Ravi K. Amaravadi, MD, assistant professor of Medicine
in the division of Hematology / Oncology at the Perelman School of Medicine and co-leader of the Cancer Therapeutics Program at Penn Medicine's Abramson Cancer Center.
«Nevertheless,
in situations where endogenous accumulation of salt to sites of infection is insufficient, supplementation of salt might be a
therapeutic option.
«
In the future, these results could also lead to new
therapeutic options for the treatment of other fibrotic diseases.»
In addition, it offers the
option to assess the brain - gut response to
therapeutic interventions including biofeedback and neuromodulation.»
The authors conclude that recurrence of an atrial tachyarrhythmia was frequent
in both groups, and that when offering ablation as a
therapeutic option to patients with paroxysmal AF who have not previously received antiarrhythmic drugs, the risks and benefits need to be discussed and treatment strategy individually recommended.
Using infectious organisms to break tumor immune tolerance may be an excellent
therapeutic option for treating cancer
in the future.
Strahl said, «We think this work will lead to a greater understanding of cancer biology, and open the door to future
therapeutic approaches for patients
in need of better treatment
options.»
As a further
therapeutic option, the researchers are pursuing the approach of using specifically developed antibodies against CEACAMs
in order to fight diseases associated with the bacterium.
Similar to high - grade gliomas, which originate
in the brain, these metastatic brain tumors are lethal, and there are very few
therapeutic options.
Because most clinicians are likely to see smokers at times when a quit date
in the next month is not planned, the current study indicates that prescription of varenicline with a recommendation to reduce the number of cigarettes smoked per day with the eventual goal of quitting could be a useful
therapeutic option for this population of smokers.
Epigenetic analysis determined that the enhancer driving MYC expression
in the leukemic cells was not Notch - dependent, but rather BRD4 - dependent, suggesting another possible
therapeutic option for MYC - expressing tumors.
In collaboration with various rehabilitation clinics, the RUB researchers have tested the feasibility of passive stimulation as a
therapeutic option: about 50 patients were treated after a stroke (sub-acute phase) and several chronic patients were treated long - term over many months.
In diabetes, we may be able to replace the defective beta cells, but regenerative medicine also offers new
therapeutic options for other organ defects and diseases.»
«Our data argue for developing new clinical trials focused specifically on using these T memory cells,
in order to determine if it would indeed be better than current
therapeutic options,» said Dr. Snyder.
Current
therapeutic options for such patients are limited, particularly when there are many metastases,» says Khalid Shah, MS, PhD, director of the Center for Stem Cell Therapeutics and Imaging (CSTI)
in the BWH Department of Neurosurgery, who led the study.
Furthermore, this study also encourages the application of iPSC - MSCs as an exciting new
therapeutic option for a range of immunological disorders and suggests that further study of the secreted factors may allow the construction of efficient cell - free therapies
in the near future.
Supportive and symptomatic treatments are currently the only
therapeutic option to delay muscle atrophy is of critical importance
in the clinics.
«The discovery that aldose reductase regulates mucus production and goblet cell metaplasia makes inhibition of this enzyme an attractive
therapeutic option to reduce mucus - related airway obstructive diseases — and for the first time gives us a real chance to alter the course of the underlying disease
in asthma and COPD.»
By better understanding FMRP's role
in this process, we may someday be able to suggest effective
therapeutic options to prevent or reverse these changes.»
However, patients are now able to participate
in two research projects aimed at understanding this disease
in order to make discoveries which may lead to better
therapeutic options.
Our proposal represents the kind of research I am interested
in, which seeks to modify natural protein variants to be used as
therapeutic options for human brain diseases.
The advanced stem cell therapy protocol available at Okyanos, which is currently not being offered
in the United States, is an important
therapeutic option for the skin manifestations of this type of systemic scleroderma.
Only 2,000 hearts become available for heart transplant annually
in the United States, leaving limited
therapeutic options for the remaining millions.
Results from these studies will provide direct evidence for the importance of these nutritional factors
in maintaining retinal health and preventing advanced retinal disease, and may reveal new
options for
therapeutic intervention.