«Given that the functional connectivity between the prefrontal cortex and amygdala is largely conserved between mice and humans,» said TSRI Graduate Student Wen - Chin Huang, the first author of the study, «we anticipate
the therapeutic strategies suggested here may be relevant for individuals on the autism spectrum.»
Not exact matches
«These data
suggest that small molecule inhibition of PRMT1 could be an impactful
therapeutic strategy in pancreas cancer.»
This
suggests that the design of rational
therapeutic strategies may remain almost as vexing as it is today.
«Our study highlights the multifaceted pathophysiology of Dravet Syndrome that includes brain, heart, and autonomic disturbances, and
suggests novel
therapeutic strategies for interventions to reduce SUDEP in this and perhaps other severe epilepsies,» says David S. Auerbach, Ph.D., of the University of Michigan.
These observations
suggest that blocking beta - arrestin - 1 may be an effective
therapeutic strategy for metastatic disease.
«Genomic data across several cancers further
suggest this
therapeutic strategy may aid many cancer patients, including those with stomach and colon cancers.»
«The study
suggests certain gut microbiota, including Ruminococcus and Blautia, may be promising targets for future
therapeutic strategies to treat metabolic disorders,» Professor Morris said.
Determining the detailed molecular mechanism that mediates the
therapeutic actions of cannabidiol may
suggest development
strategies for new drugs aimed at GPR55, according to the researchers.
«These results are particularly exciting because they
suggest that drugs directed at fusion - circular RNAs could be a powerful
strategy to pursue for future
therapeutic development in cancer,» said Pandolfi.
This study reveals how lipids control SH2 domain - mediated cellular protein interaction networks and
suggests a new
strategy for the
therapeutic modulation of pY - signaling pathways.
Moreover, preliminary experimental and clinical evidence
suggests that
therapeutic strategies aimed to treat osteoporosis may have a favorable effect on vascular calcification.»
Their study published online ahead of print in PNAS Early Edition
suggests a new
therapeutic strategy for patients with Duchene muscular dystrophy, a progressive neuromuscular condition, caused by a lack of dystrophin, that usually leaves patients unable to walk on their own by age 10 - 15.
«While it still may be possible to optimize GlyT - 1 inhibition as a treatment, these negative results
suggest GlyT - 1 inhibition is not a broadly effective or optimal
therapeutic strategy to enhance NMDA glutamate receptor function in schizophrenia.»
In a new study, published online June 6 in Nature, researchers at University of California San Diego School of Medicine and Moores Cancer Center, together with colleagues at Keio University, the University of Nebraska and Ionis Pharmaceuticals describe an innovative new model that not only allowed them to track drug resistance in vivo, but also revealed a new
therapeutic target, which early testing
suggests could provide a
strategy to arrest pancreatic cancer growth.
New research findings published in the February 2016 issue of the Journal of Leukocyte Biology,
suggest that a new
therapeutic strategy for HIV may already be available by repurposing an existing prescription drug.
«Our results in experimental models of cancer
suggest a new
therapeutic strategy based on inhibiting the microRNA machinery — or the Let - 7 microRNAs — specifically in the TAMs, which may unleash the power of mainstream immunotherapies, such as immune checkpoint inhibitors.»
It also
suggests specific
strategies for developing therapies which might have both preventative and
therapeutic benefits for this class of degenerative disease.
«Our results
suggest that blocking the activity of HOIL - 1L could be a new
therapeutic strategy for reducing inflammation in disease.»
These multi-target
therapeutic strategies for the management of cutaneous melanoma
suggest using combination of HGF / SF - Met inhibitors and chemotherapeutic drugs.
This
suggests that host glycan - lectin interactions likely mediate signals that define, in part, the transcriptional state of HIV and that host glycosylation machinery may be exploited to develop novel HIV
therapeutic strategies.
The new observations
suggest that inhibiting mitochondrial metabolism as a
therapeutic strategy may be more effective in patients that carry the Pro72Arg variant.
The ability to transform adipocytes into unique fat - burning cells may
suggest novel
therapeutic strategies for obesity.
New research proposes curcumin as a
therapeutic strategy to manage ulcerative colitis and
suggests that it may be effective enough to allow patients with inflammatory bowel disease to decrease their dosage of corticosteroids (conventional medicine) or stop taking them altogether.
Strengths: I am easy to talk to; I take an active role in the
therapeutic process, giving reading / homework assignments [if desirable], and will
suggest strategies / coping tools to expedite progress.
This training is designed to further increase the knowledge base of mental health professionals with adoption issues that may complicate their
therapeutic interventions and
suggest successful
strategies for working with adoptive families in times of crisis.