Sentences with phrase «therapeutic target against»
Furthermore, results may encourage other research groups to use the M2 channel of influenza virus as therapeutic target against the influenza A virus.
https://www.sciencedaily.com/
The study, led by ISGlobal — a centre supported by the «la Caixa» Foundation — and published in Scientific Reports, indicates that this enzyme could represent a selective therapeutic target against this broad group of parasites.
«Excitement in the brown fat field has risen significantly over last few years because its energy - burning nature makes it a potential therapeutic target against obesity and diabetes,» said Dr Lee.
Dr. Mody is leading a clinical trial investigating the role of next generation sequencing (NGS) in precision oncology for developing novel biomarkers and therapeutic targets against refractory childhood cancers.
«We believe the use of this index in future studies may help identify novel therapeutic targets against cancer,» Dr. Noushmehr said.
Not exact matches
«Because of its different origin, this enzyme could represent a good therapeutic target with selective action against all apicomplexans,» adds Luis Izquierdo, ISGlobal researcher and coordinator of the study.
«Together, our findings indicate that these molecular regulators, TRIP - Br2 and GATA3, could be viable targets for small drug molecules that could serve as potential therapeutic agents against obesity,» Liew said.
«Novel imaging model helps reveal new therapeutic target for pancreatic cancer: Antisense treatment in preclinical models shows effectiveness against deadly tumors.»
Whilst a handful of these genes including DOT1L, BCL2 and MEN1 are already established therapeutic targets, most of them are novel and open up many new possibilities for developing effective treatments against the disease.
Their results, the researchers conclude, «show that computationally designed proteins have potent anti-viral efficacy in vivo and suggests promise for development of a new class of HA stem - targeted antivirals for both therapeutic and prophylactic protection against seasonal and emerging strains of influenza.»
Examination of such mechanisms by which the brain naturally protects itself may lead to more selective cellular and molecular targets, as well as new therapeutic strategies against brain disease.
iTeos and Adimab LLC are collaborating on the discovery, development and commercialization of multiple, antibody - based therapeutic programs, with Adimab using its antibody discovery and optimization platform to identify fully human therapeutic antibodies against targets selected by iTeos.
My Honours project focused on genetically validating the Signal Transducer and Activator of Transcription 3 (STAT3) protein as a therapeutic target by using a novel transgenetic mouse model in which a short hairpin RNA directed against STAT3 can reversibly be induced by the administration of doxycycline.
A newly - engineered super small Cas9 enzyme could be used to make CRISPR more useful as a therapeutic tool against common and «undruggable» disease targets
The Company's pipeline includes cancer immunotherapies against clinically - validated targets, such as CX - 072, a PD - L1 - targeting Probody therapeutic wholly owned by CytomX, and BMS - 986249, a CTLA -4-targeting Probody therapeutic partnered with Bristol Myers Squibb.
«Targeting tau acetylation could be a new therapeutic strategy against human tauopathies, like Alzheimer's disease and FTD,» says co-senior author Eric Verdin, MD, a senior investigator at the Gladstone Institutes.
This platform has enabled the Company and its collaboration partners to discover and develop high - quality therapeutic antibodies against a variety of molecular targets, including targets that are difficult to drug with conventional antibody technologies.
Therefore, this complex is a highly promising therapeutic drug target against diabetes, obesity, Wolff - Parkinson - White Syndrome, cancer, and aging.
«We have created a potentially much less expensive approach to making a therapeutic cancer vaccine that, while targeting a single tumor antigen, generates an immune response against multiple antigens.
This study just found (in mice) that the common therapeutic target for the anti-TNF medication treatment of IBD, may actually protect against intestinal inflammation by inhibiting pathogenic T - cells.