Extracellular interactions are excellent
therapeutic targets because they are directly accessible to systematically delivered drugs such as monoclonal antibodies.
It's an important
therapeutic target because catastrophizing is linked to the development of chronic pain after surgery or an episode of acute pain.
Not exact matches
«Excitement in the brown fat field has risen significantly over last few years
because its energy - burning nature makes it a potential
therapeutic target against obesity and diabetes,» said Dr Lee.
The c - MYC pathway appeared to some researchers to be an unlikely
therapeutic target for beta cell regeneration
because past studies had found it to cause beta cell death when activated in high doses.
«
Because of its different origin, this enzyme could represent a good
therapeutic target with selective action against all apicomplexans,» adds Luis Izquierdo, ISGlobal researcher and coordinator of the study.
According to Dr. Irie, the research is especially important
because it supports the potential
therapeutic value of
targeting PTK6 in ER + breast cancers, which constitute the most common subtype of breast cancer.
Drugs that
target KORs have shown promise as
therapeutic candidates
because of their efficacy for treating chronic itch and relieving pain.
«Usually that's useless
because they are already inactive in that state, but this finding suggests we might be able to find new
therapeutic approaches to
target these diseases.»
Because of the ease with which the CRISPR / Cas9 system can be applied, it has quickly become a robust tool for generating accurate genetic disease models in the laboratory and for identifying novel
therapeutic targets in the clinic.
Robust prognostic gene signatures and
therapeutic targets are difficult to derive from expression profiling
because of the significant heterogeneity within breast cancer (BC) subtypes.
Because viruses have evolved such effective methods for finding their
target and utilizing the host cells» own molecular machinery, scientists are modifying viruses into long - lasting
therapeutic vehicles that can deliver drugs to specific cells or tissues or selectively
target and destroy tumors.
Because increased intestinal permeability appears to be a central mechanism in the pathogenesis of NSAID enteropathy, it becomes a potential
therapeutic target for prevention.