Sentences with phrase «therapies are in development»

More niche therapies are in development, which means the potential pool of study participants is diminishing.

Right now, the first CRISPR gene therapies are in development, but they are not built on a «standard stack» and require a lot of custom work for each indication - these therapies will be coming into the clinic and hopefully get approved the coming couple years, and after that there could be significantly more investment into standard tools.»

Not exact matches

Alder is additionally evaluating ALD1910, a preclinical product candidate also in development as a migraine prevention therapy.

Thanks to developments in gene therapy, that day might not be so far away.

And there have been developments in cellular therapies to treat cancer, with two treatments aiming for approval by the end of 2017.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

The company is also seeking deeper inroads into rare diseases, with a number of assets in late - stage development, and last year it scored a major regulatory win when Europe approved its «bubble boy syndrome» gene therapy Strimvelis.

Chiesi Ventures want to be instrumental in funding great research and development opportunities for therapies that can provide a hope for the patients and their families.

That therapy for treating melanoma is already in the development pipeline, along with 906 other biologics targeting over 100 diseases from autoimmune disorders to viruses.

Continuous therapy groups are carried on as well as individual counseling and Adult Intereducational Mission Groups, which combine sensitivity training and the development of skills in writing devotional materials.

In discussing the use of ideals and action plans in therapy he emphasized that these need to be «authentic,» that is, in line with the natural development of the persoIn discussing the use of ideals and action plans in therapy he emphasized that these need to be «authentic,» that is, in line with the natural development of the persoin therapy he emphasized that these need to be «authentic,» that is, in line with the natural development of the persoin line with the natural development of the person.

(3) The rapid increase in the influence of his approach since his death is evident in the development of several gestalt therapy training institutes and the burgeoning writings of creative therapists who continue to modify, amplify, and enrich his original formulation.

Along with the rise in the incidence of such problems (or perhaps it is simply the rising expectation that sex «should» be enjoyable), the development of sex therapy methods and the generally greater freedom to talk about the subject openly, there has also been an increase in the number of sex therapy clinics and counselors.

In their thought, the ego is seen in ways that are very similar to the «self» in contemporary therapies — as the potentially effective coordinator of the overall integration and development of the whole personalitIn their thought, the ego is seen in ways that are very similar to the «self» in contemporary therapies — as the potentially effective coordinator of the overall integration and development of the whole personalitin ways that are very similar to the «self» in contemporary therapies — as the potentially effective coordinator of the overall integration and development of the whole personalitin contemporary therapies — as the potentially effective coordinator of the overall integration and development of the whole personality.

Recent developments in «milieu therapy» and the «therapeutic community» approach indicate that therapeutic goals can be achieved in much larger groups than had been thought possible in orthodox group therapy theory.

In circle 3... and circle 4..., dynamic education, group therapy, growth groups [and organizational development] are effective methods.

The diverse cluster of therapies whose aim is to facilitate creative change in relationships and in social systems represents a highly significant development in contemporary therapies.

`... Interactions between in inflammation and the brain appear to drive the development of depression and may contribute to non-responsiveness to current antidepressant therapies... [The] inevitability of our evolutionary past is apparent in the high rates of depression that are seen in society today.»

She's trained in Nobody's Perfect parenting, Hand in Hand Parenting, Expressive Play Therapy and continues to take courses on child development, trauma, birth and adolescence.

Oftentimes, I do get referrals for physical therapy for babies who are either experiencing plagiocephaly and or corticolis, which is the shortening of the neck muscles, sternocleidomastoid and all the others that are around it that contributes to asymmetries in development and developmental delays.

Today on Parent Savers, we have Holly Gangwer — Speech Language Pathologist with K.I.D.S. Therapy Associates and she's helping us learn about Speech Development in our kids.

Whether your multiples are in an Early Intervention program or receiving therapy through the school district, their development is measured by how well they meet goals and objectives.

However, because parents worry about developmental delays that could affect a child later in life, this uneven development in a child who was born prematurely might cause the parents to seek therapy when none is needed.

After one of our very first play therapy appointments, which all of my professional (I have a Master's in education / child development) friends and even my mom (a certified psychotherapist) were against because there is not a lot of research to support play therapy, I took the kids to a farmers market and there was a book exchange table.

The Therapy for Black Girls Podcast is a weekly conversation with Dr. Joy Harden Bradford, a licensed Psychologist in Atlanta, Georgia, about all things mental health, personal development, and all the small decisions we can make to become the best possible versions of ourselves.

We offer a number of therapeutic services for children from one year of age through adolescence that include individualized speech and language therapy, parent training to facilitate language development in children who are late talkers or stuttering, and interventions to facilitate social communication and pragmatics.

less than or equal to lamivudine Acquired Immune Deficiency Syndrome Antiretroviral therapy, usually means 1 - 2 drugs, used in early studies Antiretroviral zidovudine (also known as ZDV) Breastfeeding Baby Friendly Hospital Initiative Breastfeeding and HIV International Transmission Study Combined antiretroviral therapy Centers for Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug therapy, usually means 1 - 2 drugs, used in early studies Antiretroviral zidovudine (also known as ZDV) Breastfeeding Baby Friendly Hospital Initiative Breastfeeding and HIV International Transmission Study Combined antiretroviral therapy Centers for Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug therapy Centers for Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug as AZT)

2) Last Child in the Woods: Saving Our Children From Nature - Deficit Disorder by Richard Louv — read this concurrently with # 3 3) Smart Moves: Why Learning Is Not All in Your Head by Carla Hannaford — which will probably lead to curiosity about # 4 4) Brain Gym or similar therapies offered by # 5 and # 6 5) The National Association for Child Development -LRB--RRB- 6) The Developmental Movement Center, Seattle [phone] ″

The Therapy for Black Girls Podcast is a weekly conversation with Dr. Joy Harden Bradford, a Licensed Psychologist in Atlanta, Georgia, about all things mental health, personal development, and all the small decisions we can make to become the best...

The Therapy for Black GirlsTM Podcast is a weekly conversation with Dr. Joy Harden Bradford, a licensed Psychologist in Atlanta, Georgia, about all things mental health, personal development, and all the small decisions we can make to become the best...

Their approach to this training has been to collaborate with other experts in the fields of behavioral development, developmental anatomy, and occupational therapy to provide trainees with a well rounded approach to working with kids through yoga.

I have enjoyed serving you on the OKAPT Board the last 2 years and have tried to focus on making communication forefront though helping in the development of the new website, being on a news segment for National Play Therapy Week in OKC, and through helping to run OKAPT Lunch - and - Learn play therapy trainings Therapy Week in OKC, and through helping to run OKAPT Lunch - and - Learn play therapy trainings therapy trainings in OKC.

Occupational therapy allows therapists to utilize their creative thinking skills while also relying on their knowledge of science, development, and the body / brain to be effective in their role as an OT.

In a press statement, the State's Commissioner for Information and Strategy, Mr. Steve Ayorinde congratulated the parents of the students and all concerned stakeholders over the development, just as he said the students would undergo series of medical tests and trauma therapy before they are reunited with their families.

Drugs that impact DNA methylation are increasingly a target for drug development; in fact, several of these therapies are already in clinical use for certain cancers.

«I think it awakens the possibility of gene therapy for neuropsychiatric diseases,» says Husseini Manji, a senior investigator at Johnson & Johnson Pharmaceutical Research & Development in Titusville, N.J., who was not involved in the study.

Today, light therapy in incubators prevents this dramatic development if it is applied in time.

In addition, the development of therapies that could potentially halt patients» progression from pancreatic inflammation to diabetes has been hampered by the long lead times needed in order to tell whether a given therapy has an effecIn addition, the development of therapies that could potentially halt patients» progression from pancreatic inflammation to diabetes has been hampered by the long lead times needed in order to tell whether a given therapy has an effecin order to tell whether a given therapy has an effect.

Inhibitory cell - based neuro - therapy is a new approach and has shown promise to date in early animal studies, warranting further development,» says Cory Nicholas, a co-first author.

Researchers at the Medical College of Wisconsin (MCW) have linked a specific protein to the development of post-viral infection asthma, which is the first step in generating a novel type of asthma therapy designed to prevent development of post-viral asthma in young children.

The analysis suggests that alternative therapies for certain mild infections — which may be easier to develop — could indirectly slow development of antibiotic resistance in more dangerous bugs.

The investigators» experiments in mice suggest that the receptors» activation directly aggravates airway constriction and — if the same process is active in people — may be a promising new target for the development of drug therapies.

The journal provides cutting - edge research including results from animal models that are likely to apply to patients, studies in human tissue that provide new information about therapies or disease, and innovative reports of drug discovery and development.

Development of new therapies such as this one could help in the management of common gastrointestinal disorders such as irritable bowel syndrome that could be also triggered by wheat containing food.

This pathway is currently the focus of development of targeted therapy for moderate - to - severe eczema, suggesting that these same agents being tested in adults could also be useful in young children.

«It is expected that this study will lay the foundation for developing a new class of potent and effective cancer therapies and the development of reagents targeting epigenetic events in immune - mediated diseases as well as other epigenetically - influenced diseases,» said Alani, who also is chief of dermatology at Boston Medical Center.

Understanding what happens with the UPR in disease is key to illuminating the normal operation of this essential pathway — and to providing insights into the development of targeted therapies.

Advanced clinical trials are underway for at least 10 investigational therapies that have shown promise in slowing or blocking development of Alzheimer's disease.

She continued: «Therefore, in further studies, we should investigate how and at what point DPP4 inhibitors can be used in diabetes therapy to prevent the development of non-alcoholic fatty liver disease.»

The research was published in the scientific journal Nature Genetics this week and scientists hope it will provide another potential target for therapy development.