Sentences with phrase «therapies by engineering»

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February 2, 2017 By Ann Perry http://mbd.utoronto.ca/ When Arif Aziz learned last fall about a new independent study project that was bringing together MBA candidates and PhD students in health sciences and engineering to map the global market for stem cell therapies, he jumped at the opportunity.
By varying the compositions of lipids, cues, and diffusible factors in the scaffolds, we engineered a very versatile and flexible platform that can be used to amplify specific T cell populations from blood samples, and that could be deployed in existing therapies such as CAR - T cell therapies,» said Mooney, Ph.D., a Core Faculty member at the Wyss Institute and leader of its Immunomaterials Platform.
To strengthen its clinical research profile, Dresden has created a strategic plan, to be funded by the German Research Ministry (BMBF), that focuses on three aspects of clinical research: tissue engineering and development of physical and molecular medical technologies for clinical application; therapeutic strategies after cell and tissue damage; and diagnosis and therapy of malignant diseases.
The proposed clinical trial, in which researchers would use CRISPR to engineer immune cells to fight cancer, won approval from the Recombinant DNA Advisory Committee (RAC) at the U.S. National Institutes of Health, a panel that has traditionally vetted the safety and ethics of gene therapy trials funded by the U.S. government and others.
As demonstrated by the breadth of clinical trial involvement shown above, CCIR members are testing the utility of immune checkpoint blockade in lymphoma (shown by Dr. Allison to be effective against melanoma), genetic engineering in cell therapy (e.g., CD19, CXCR2, TGF - β DNR), and TLR agonists or IL - 2 in vaccine formulations as well as some novel combination therapies, such as the infusion of tumor - reactive lymphocytes from HLA - matched donors who were vaccinated with a lymphoma idiotype.
These partnerships foster the exchange of scientific and engineering knowledge and broaden the development of students and faculty and by encouraging them to pursue technologies related to regenerative medicine and training clinicians in the implementation of regenerative therapies.
Thus, this rational transcript engineering approach may represent a unique therapeutic opportunity for a wide range of diseases caused by mutations in the mitochondrial genome for which current effective therapies are lacking (2)
He is a major donor to and serves as an advisor to the Methuselah Foundation, dedicated to extending the healthy human lifespan by advancing tissue engineering and regenerative medicine therapies.
Here, we address that unmet need for cell therapy biomanufacturing, in part by leveraging existing decision - engineering frameworks for biopharmaceuticals to build on the nascent body of published work geared towards cell therapies.
Prof. Su's current research fields include the design, the synthesis, the property study and the molecular engineering of nanostructures and highly organized and hierarchically self - assembled porous materials, bio-integrated living and bio-inspired materials including leaf - like materials by the immobilization of living organisms and biomaterials for catalysis, photocatalysis, CO2 reduction and water splitting, artificial photosynthesis, nanotechnology, biotechnology, information technology, energy storage and conversion, cell therapy and biomedical applications.
Furthermore, by combining this information with the characterization of mice genetically engineered to develop lung tumours, we attempt to elucidate the key genes driving lung cancer initiation, progression and response to therapy.
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Leanne's journey from engineer designing submarines — to acupuncturist — to artist — to color and light therapy expert... is driven by her lifelong love of science, holistic medicine, spiritual growth and a true desire to help others.
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