«Developing new
therapies for disease is a wonderful thing.»
Robert D. Schreiber, Ph.D., an associate director of CRI's Scientific Advisory Council based at Washington University School of Medicine in Saint Louis, Missouri, developed a new model of breast cancer that more closely resembles the progression of hormone receptor - positive disease in humans, overcoming a major obstacle in the study of breast cancer and the development of new immune - based
therapies for the disease.
The SMDC has allowed Gladstone scientists to design molecules to modulate the functions of proteins or specific cellular phenotypes and, most significantly, screen for drugs that could be used as
therapies for disease.
Deepak Srivastava, MD, and Christina Theodoris, an MD / PhD student, created mouse models of CAVD that may be used to test drug
therapies for the disease.
Gladstone established the Assay Development and Drug Discovery Core to help scientists accelerate their research into target and drug - discovery phases and move their findings into clinical trials and potential
therapies for disease.
The goal of everyone in the HD community is to come up with effective
therapies for the disease.
The Leukemia Program is dedicated to integrating laboratory and clinical research to increase our understanding of leukemia and to develop new, more effective
therapies for the disease.
8/27/2008 First Gene Associated with Dry Macular Degeneration Found Findings indicate possible adverse consequences to new RNA therapies In a study that underscores the important role that individual genetic profiles will play in the development of new
therapies for disease, a multi-institutional research team — led... More...
Another area where corporate partners could be important is in developing devices for getting data out of the nervous system and developing new
therapies for disease conditions.
In the era of personalized cancer therapy, patients with TNBC remain at considerably higher risk of relapse and death than patients with other breast cancer subtypes, due to the aggressive nature of TNBC and the lack of newer targeted
therapies for the disease.
The findings, published in the journal ACS Central Science, shed new light on the underlying mechanisms of CF and could lead to improved prognosis and better
therapies for a disease which is quite variable, affecting different children in different ways, say researchers.
«We desperately need new
therapies for this disease, and regenerative medicine approaches have shown great promise in laboratory models and in clinical trials for other conditions.»
So they are a potential target for new
therapies for the disease which is incurable according to the present state of research.
The findings, available online in the Journal of Infectious Diseases, may lead to the development of new preventive
therapies for the disease.
Understanding the mechanisms of inflammation in rheumatoid arthritis is important for the design of new
therapies for this disease.
But experts say it's uncertain whether this test tube success will lead to better
therapies for the disease.
Instead of getting a better, updated
therapy for a disease every decade or so, we might begin to see second - generation cell therapies in a few years.
He envisions a future in which Boomers become strong advocates for medical marijuana because it «may be a less expensive and a more desired
therapy for diseases» that are impacting them.
Researchers at the University of Louisville have discovered a mechanism involved in skeletal muscle repair that may enable clinicians to boost the effectiveness of adult stem cell
therapies for diseases such as muscular dystrophy.
Our development pipeline is focused on areas of high unmet medical need, as we pursue new
therapies for diseases with few or no treatment options.
Genzyme, for example, is committed to developing innovative
therapies for diseases such as malaria and sleeping sickness that have largely disappeared in the industrial nations but affect millions in Third World countries.
When the World Health Organization recently named blood transfusions from Ebola survivors as its priority experimental
therapy for the disease ravaging west Africa there was only one major problem: no data indicating that such transfusions work.
Dr. Lazaridis says this molecule therefore should be further examined as a target of
therapy for the disease.
«If we can confirm selumetinib's effectiveness in treating advanced uveal melanoma in this follow - up trial, it will become the standard
therapy for this disease, forming a foundation for new drug combinations that could maximize selumetinib's MEK - inhibitor effect,» he said.
Unraveling the underlying mechanism could help pave the way toward making phages a targeted
therapy for diseases like cholera.
Dr Wenxin Wang is trying to uncover
therapies for diseases such as diabetic ulcers and Epidermolysis Bullosa, which causes chronic skin conditions: «We are currently investigating the use of these new materials for biomedical applications such as drug / gene delivery, cross linkable hydrogel materials and skin adhesives.
With this new understanding of the enzyme, called Inositol trisphosphate 3 - kinase B (ItpkB), scientists are closer to improving
therapies for diseases such as bone marrow failure syndrome, anemia, leukemia, lymphoma and immunodeficiencies.
Obiang speaks of his hopes that scientists will find
therapies for diseases, such as AIDS, that are currently seen as incurable.
«While performing a post-radiation biopsy is not currently a standard practice, the fact that it was done as part of this clinical trial afforded the opportunity to more precisely quantify the importance of successful local
therapy for this disease,» explains Dr. Krauss.
If the approach also works with human cells, it could eventually lead to cell
therapies for diseases like inherited leukodystrophies — disorders of the brain's white matter — and multiple sclerosis, as well as spinal cord injuries.
However, the study led by Pyle found that the current methods are inefficient; they produce immature cells that are not appropriate for modeling Duchenne in the laboratory or creating a cell replacement
therapy for the disease.
«Since mGluR5 is considered a target for treating a variety of neurological disorders, including Parkinson's disease and Fragile X Syndrome, our research may have implications for
therapies for diseases beyond depression.»
There are still no suitable
therapies for these diseases.
The collaborative research project will execute a multi-year program to develop genetic
therapy for the disease.
Dr. Torkamani's research covers a broad range of areas centered on the use of genomic technologies to identify the genetic etiology and underlying mechanisms of human disease in order to define precision
therapies for diseased individuals.
CAMBRIDGE, Mass., Nov. 16, 2016 — Proclara Biosciences, a biotechnology company developing novel
therapies for diseases caused by protein misfolding, today announced that the U.S. Patent and Trademark Office has issued two new patents related to the company's proprietary General Amyloid Interaction Motif (GAIM) platform.
CAMBRIDGE, Mass., Mar. 1, 2017 — Proclara Biosciences, a biotechnology company developing novel
therapies for diseases caused by protein misfolding, today announced that Franz Hefti, Ph.D., president and chief executive officer, will present a company overview at the Cowen and Company 37th Annual Health Care Conference on Wednesday, March 8, 2017 at 1:30 p.m. ET in Boston.
Cambridge, MA, September 07, 2016 — Proclara Biosciences, a biotechnology company developing novel
therapies for diseases caused by protein misfolding, today announced that it has initiated a Phase 1b clinical trial evaluating NPT088, its lead development candidate for Alzheimer's disease.
These vaccines aim to protect against future infections and look to create new
therapies for diseases already affecting people.
The trial marks the first approved clinical trial in the ITN's effort to develop more effective
therapies for diseases such as diabetes, kidney disease, autoimmune diseases, and allergy and asthma.
These patients need the benefit of JAK inhibition to be incorporated into the context of combination
therapy for disease management.
Development of a comprehensive system which can enrich hPSC - CMs will be ultimately useful for cell
therapy for diseased hearts, human cardiac disease modeling, cardiac toxicity screening, and cardiac tissue engineering.
Pembrolizumab, which has already been shown safe and effective as monotherapy for advanced, non-squamous non-small cell lung cancer (NSCLC), might also be an effective component in combination
therapy for the disease.
I believe these techniques deserve clinical testing as
therapies for all diseases associated with disrupted circadian rhythms.
As an internationally recognized expert on chelation therapy, Dr. Gordon is now attempting to establish standards for the proper use of oral and intravenous chelation therapy as an adjunct
therapy for all diseases.
Amgen takes a «biology first» approach, using cutting - edge science and technology to study human biological mechanisms in search of
therapies for diseases.
There is no reported effective
therapy for this disease.
Targeted
therapy for this disease is difficult because we still do not have a firm understanding of what causes it.
A relatively new specialty designed to save the injured teeth, veterinary endodontists perform gum and jaw surgeries, root canal
therapy for diseased or injured tooth pulp, and treat cracked and broken teeth by either extracting or placing a bonded sealant on the ailing tooth.
Senior health care implies both preventive and therapeutic approaches to medicine, including nutrition, dental care, and exercise as well as
therapy for diseases.