Sentences with phrase «therapy than the disease»

Not exact matches

less than or equal to lamivudine Acquired Immune Deficiency Syndrome Antiretroviral therapy, usually means 1 - 2 drugs, used in early studies Antiretroviral zidovudine (also known as ZDV) Breastfeeding Baby Friendly Hospital Initiative Breastfeeding and HIV International Transmission Study Combined antiretroviral therapy Centers for Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug therapy, usually means 1 - 2 drugs, used in early studies Antiretroviral zidovudine (also known as ZDV) Breastfeeding Baby Friendly Hospital Initiative Breastfeeding and HIV International Transmission Study Combined antiretroviral therapy Centers for Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug therapy Centers for Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug as AZT)

The biological complexity of cancer and other diseases demands a more formidable arsenal of therapies than currently available.

The fact that TAS - 102 temporarily halted the disease in many of these patients suggests that it operates through a different biochemical pathway than 5 - FU, and therefore may serve as an alternative to standard therapy.

Women, on average, experience coronary artery disease 10 years later than men and have lower smoking rates than men, both of which may partially contribute to the sex disparity in statin therapy.

Patients who got it lived about 4 months longer, nearly 26 months total, than those who didn't — but that, say company executives, is still more than any other therapy has managed for this disease in a randomized trial.

In the U.S. alone, therapy for chronic kidney disease is likely to exceed $ 48 billion per year, and the end - stage kidney disease program consumes 6.7 percent of the total Medicare budget to care for less than 1 percent of the covered population.

«With more than 1.7 million people dying globally from TB each year and the rise of strains that are resistant to drug treatment, we need a better way to prevent this disease,» said the study's principal investigator Louis Picker, M.D., who is the associate director of the OHSU Vaccine and Gene Therapy Institute and a professor of pathology, molecular microbiology, and immunology in the OHSU School of Medicine.

Researchers from Massachusetts Eye and Ear / Harvard Medical School have found that patients who were prescribed corticosteroids as part of treatment for Lyme disease - associated facial paralysis had worse long - term outcomes of regaining facial function than those who were prescribed antibiotic therapy alone.

In addition to providing insights regarding selection of treatment, this blood test may also prove helpful in assessing the presence of residual disease, recurrence, or relapse and detection of therapy - resistant cancer cells more quickly than conventional tissue - based methods.

At a meeting of the Society for Neuroscience in Washington DC last week, Victor Henderson and colleagues from the University of Southern California in Los Angeles, presented findings that suggest women on oestrogen therapy are 40 per cent less likely to develop the disease than those who are not.

The same process has been studied as a potential genetic therapy for more than a decade, because you can target any disease gene with matching dsRNA.

While the disease can take many forms, recent advances have better characterized how lymphoma cells proliferate and interact with other cells and tissues, leading to the development of powerful, targeted therapies with fewer side effects than traditional approaches.

In Cohort B — those who received pembrolizumab as first - line therapy — 12 of 52 patients, or 23 percent, saw tumors shrink by more than 30 percent, while the disease was stabilized in nine of them, or 17 percent.

One clinician who has not waited for controlled clinical studies is California osteopath David Steenblock, who offers stem cell therapy for more than 20 diseases, including Alzheimer's, traumatic brain injury, Parkinson's, arthritis, stroke, and heart disease.

The drop in hormone use dates back to July 2002, when the Women's Health Initiative, a 15 - year study tracking the health of more than 160,000 women, abruptly ended its long - term study of estrogen - progestin hormone replacement therapy because women taking the drugs faced an elevated risk of invasive breast cancer and heart disease.

Analyzing more than 120 million patient records and identifying trends of co-occurrence among hundreds of diseases, they created a unique genetic map that has the potential to guide researchers and clinicians in diagnosing, identifying risk factors for and someday developing therapies against complex diseases.

«Understanding how maternal exposures impact obesity - related disease such as nonalcoholic fatty liver disease will allow us to develop lower cost preventative therapies to utilize up front rather than awaiting complications down the road.»

Regardless of disease stage, patients who received surgery lived an average of 57 months, compared to less than 12 months for patients who received only non-surgical treatment (such as chemotherapy or radiation therapy), and 1.4 months for patients who received no treatment at all.

«The dog has a retina very similar to ours, much more so than mice, so when you want to bring a visual therapy to the clinic, you want to first show that it works in a large animal model of the disease,» said lead researcher Ehud Isacoff, professor of molecular and cell biology at UC Berkeley.

«Despite having good treatments available, current reports suggest that fewer than half of individuals who need therapy are actually getting appropriate HIV medicine to control their virus, leading to more transmission of disease,» says lead study author Maunank Shah, M.D., Ph.D., an assistant professor of medicine at the Johns Hopkins University School of Medicine.

Although there remains no cure for Alzheimer's, researchers hope that testing potential drugs or therapies prior to mental decline will prove to be more successful than previous attempts at finding the most effective treatment in the battle against the debilitating disease.

There are now more than 100 gene therapy clinical trials aimed toward cancer, genetic diseases (such as ADA deficiency, cystic fibrosis and hemophilia A), infectious diseases (including AIDS) and autoimmune diseases (such as rheumatoid arthritis).

Creating a federal initiative to support development of new therapies for ultra-rare diseases occurring in fewer than one in 250,000 births annually.

«It affects many more children than brittle bone disease, so we're very hopeful that sclerostin antibody therapy will be a useful treatment for them as well.

«Sex reassignment surgery may be better for transgender women's health than hormones only: Study investigates metabolic disease risk after receiving only hormone therapy compared to surgery.»

Although the study's approach wasn't a sure bet, the researchers hoped to go further than any other gene therapy trial yet for this relatively common inherited disease that fills people's lungs with sticky mucus that promotes deadly infections.

More than one - third of those patients, for whom new American College of Cardiology / American Heart Association guidelines would recommend statin therapy, were reclassified as being at very low risk for cardiovascular disease.

More than 10 percent of patients treated with aspirin therapy for primary cardiovascular disease prevention were likely inappropriately prescribed medication, according to a new study in the Journal of the American College of Cardiology that examined practice variations in aspirin therapy.

Given the poor prognosis and limited treatment options in pancreatic cancer, new therapies to combat the disease are desperately needed: Earlier this year, the American Cancer Society reported that it is estimated that in 2016, nearly 42,000 people will die from the disease, surpassing the number of deaths from breast cancer by more than 1,000.

While a new generation of safer, more effective oral medications to treat hepatitis C patients may cost tens of thousands of dollars for a 12 - week regiment, investing in these new therapies could generate savings estimated at more than $ 3.2 billion annually in the U.S. and five European countries, according to a new study (abstract 228) released today at Digestive Disease Week ® (DDW) 2015.

In the era of personalized cancer therapy, patients with TNBC remain at considerably higher risk of relapse and death than patients with other breast cancer subtypes, due to the aggressive nature of TNBC and the lack of newer targeted therapies for the disease.

This approach for gene therapy to treat fatty liver disease, for example, might prove both safer and more effective than reengineering cells in the liver itself.

YOKOHAMA, JAPAN — For more than a decade, stem cell therapies have been touted as offering hope for those suffering from genetic and degenerative diseases.

Our approach is to study more than one or two serial recurrences of the disease, adding information about the response to therapy and natural progress of ovarian cancer,» adds J. Brian Szender, MD, MS, senior author and a fellow in Gynecologic Oncology at RPCI.

«Vaccination normally generates protective immunity that prevents the disease for years in a population at a relatively low cost; whereas, antiviral therapies can only be treating the diseases at a higher cost rather than offer long - term protection.»

Inspired by a grandfather who had Alzheimer's disease, Dr. Mucke founded Gladstone's neurological research program 15 years ago and today leads more than 100 students, postdocs, research scientists and principal investigators in the search for new understanding of and therapies for some of the world's most devastating illnesses — including Alzheimer's, Parkinson's, ALS, and multiple sclerosis.

Included among the numerous recipients of Mr. Sanford's gifts, that total more than one billion dollars, are: the Edith Sanford Foundation for Breast Cancer that was created in 2012 by a gift of $ 100 million in honor of Mr. Sanford's mother who died of breast cancer when he was four years old; the Sioux Valley Hospitals and Health System, which renamed itself Sanford Health in 2007, in recognition of a $ 400 million gift; a $ 125 million gift in 2014 to establish Sanford Imagenetics, a program that will integrate genomic medicine into primary care for adults; the University of California San Diego which received a $ 100 million gift for the creation of the Sanford Stem Cell Clinical Center in 2013 to accelerate the translation of stem cell research discoveries by advancing clinical trials and patient therapies; the Burnham Institute for Medical Research that received a $ 50 million gift in 2010, and recognized its appreciation for both this and a 2008 gift of $ 20 million to the Sanford Center for Childhood Disease research at Burnham by then changing its name to Sanford Burnham Medical Research Institute; a $ 70 million gift to establish a particle physics laboratory named the Sanford Underground Research Facility; and the San Diego Consortium for Regenerative Medicine which received a gift of $ 30 million in 2008 and expressed its gratitude by renaming itself the Sanford Consortium for Regenerative Medicine.

AFM supports each year more than 400 research programs, among them more than 30 clinical trials in gene therapy or cellular therapy concerning for example muscular, eyes, skin or blood diseases.

A small, phase 1 trial, published early online in the journal Radiology, found that this approach, designed to treat just the diseased portion of the prostate rather than removing or irradiating the entire gland, is safe and can be performed without the troubling complications associated with more aggressive therapies.

Microscopic models — half living, half not — may prove more reliable than animals in explaining human disease and testing therapies.

According to an international clinical trial led by Sylvia Adams, MD, associate professor of medicine, breast tumors shrank by more than 30 percent in 12 (23 percent) of 52 patients who received pembrolizumab as first - line therapy, and the disease stabilized in 9 additional patients (17 percent).

«C - Path's initiative to identify and position Crohn's disease - specific biomarkers for regulatory endorsement is a pivotal step in getting improved therapies into the hands of people living with Crohn's disease more quickly than currently possible.»

Novel drug therapies and novel indications of drug therapy, e.g. tyrosine kinase inhibitors in lung disease other than lung cancer, biological treatments for asthma, COPD, cystic fibrosis and interstitial lung disease.

As part of our mission, MDA funds research to accelerate treatments and cures for DMD and more than 40 other neuromuscular diseases, and we're proud to have supported this work that is sure to help shape DMD therapies under development today and in the future.»

«The strong evidence that abnormal TDP - 43 protein is involved in the development of ALS, coupled with models that may replicate ALS more faithfully than other tools, may speed development of therapies for the thousands of individuals diagnosed with this devastating disease.»

Inclusion Criteria: • The participant may have no more than 2 prior lines of systemic therapies (neoadjuvant and adjuvant therapies will not be considered as a prior line of therapy) for advanced or metastatic disease and is suitable to receive gemcitabine and docetaxel therapy.

This approach may also be applicable to a number of rare genetic diseases caused by splicing defects, including ataxia telangiectasia, congenital disorder of glycosylation, and Niemann - Pick disease type C. Although the three DMD studies referenced here represent a great step forward for CRISPR gene therapy, it's important to realize that DMD is a simpler case than other genetic diseases we'd like to treat with CRISPR.

«Much to our surprise, the trial showed that patients receiving standard therapy compared to those receiving cetuximab with standard therapy had no difference in outcomes,» said study author Dr. Steven Alberts, a professor of oncology at the Mayo Clinic College of Medicine in Rochester, Minn. «It also indicates that disease in earlier stages may be different than diseases in later stages.»

Reviews of clinical trials on hypnosis have concluded that the evidence of its effectiveness for smoking cessation is insufficient, but other research shows promise: The preliminary results from a small 2007 study of smokers hospitalized with cardiopulmonary diseases showed that the patients who chose to participate in a hypnotherapy session were more likely to be nonsmokers six months later than patients who chose nicotinereplacement therapy (NRT) alone.

Since being designed by Dr. Wilder more than 90 years ago, ketogenic therapies have been used to successfully treat headaches, sleep disorders, type 2 diabetes, and Alzheimer's disease.