Sentences with phrase «therapy trial so»

Despite expectations of a rapid breakthrough, no cystic fibrosis gene therapy trial so far has been able to show long - term clinical improvement.

Not exact matches

So far, its trials have shown it can improve outcomes when used alongside other multiple myeloma drugs and that could offer it some insulation if the market gets disrupted by new treatment approaches, such as gene therapy.

He now is a co-investigator in the first randomized clinical trial comparing proton therapy with more conventional radiation — something he acknowledges should have happened before so much use.

But billions of dollars have poured into large - scale clinical trials of amyloid - lowering therapies that so far have failed.

Human trials are even costlier, so for now, Sweeney says, IGF - 1 and myostatin gene therapies remain on the distant horizon.

Therapy could come in the form of new drugs, but some experts suspect drug trials have failed so far because compounds were tested too late in the disease's progression.

So - called phage therapy is widely used in Eastern Europe and is currently undergoing one U.S. clinical trial.

But in the meantime, it would help if we could identify who won't benefit from standard treatment, so we can spare them the debilitating effects of chemotherapy and get them into clinical trials for experimental therapies that might be more effective.»

Roughly 20 percent of patients with age - related macular degeneration suffer from abnormal blood vessel growth and vascular leakage, says Campochiaro, and so may be helped by this new therapy, if it proves to work in clinical trials.

But most large clinical trials of ACEI / ARB exclude patients with the most advanced stage of CKD predialysis, perhaps out of concern that the drugs can cause renal failure and the need for dialysis, so it remains unclear whether that therapy is effective in patients with advanced CKD, according to the study background.

BETHESDA, MARYLAND — An investigation into whether gene therapy killed a 36 - year - old woman in an arthritis trial has so far come up empty.

So far the therapy has only been performed in mice, but David Scheinberg and his colleagues at Memorial Sloan - Kettering Cancer Center in New York plan to begin human trials in 2002.

Within the past 10 years or so, lentiviruses have shown promise in clinical trials (1 — 3), and adenoassociated viruses (AAVs) have been used in the first approved gene therapies in the Western world (4).

These trials, unlike the unproven therapies, have been approved by the appropriate regulatory agencies and will be rigorously tested so that the risks and benefits are more fully understood before (hopefully) being made available to patients.

Dr. June: Our initial pilot trial was for 10 patients, and was so - called «third line» therapy for patients who have progressive leukemia after having had at least two different kinds of FDA - approved therapy.

«With so few patients aged 75 or older enrolled in clinical trials, critical information on the safety and effectiveness of new therapies in this age group is greatly lacking,» she said.

A so - called Phase I clinical trial is when a new drug or a new formulation of a drug, or a new combination therapy for that matter, is tested in humans for the first time.

Despite the marginal improvements in survival of patients suffering from malignant glioma treated with gene therapy vectors, the clinical trials conducted so far using viral vectors, in particular adenoviral vectors, have proven that the use of adenoviral vectors is a safe therapeutic approach, even in large, multicenter, phase 3 clinical trials.

So these types of rejuvenation therapy already exist in the sense of prototypes and trial treatments.

So in some cases, for example a patient with severe pain who has not done well with several steroid or other drug injections and physical therapy, and who presents to the doctor with back pain so severe that he can't walk — that patient might be considered a candidate right then for a triaSo in some cases, for example a patient with severe pain who has not done well with several steroid or other drug injections and physical therapy, and who presents to the doctor with back pain so severe that he can't walk — that patient might be considered a candidate right then for a triaso severe that he can't walk — that patient might be considered a candidate right then for a trial.

Many states have laws prohibiting the treatment of cancer with anything other than conventional therapies (surgery, radiation etc) so it has been difficult to set up clinical trials for nutrition.

For the recently diagnosed hyperthyroid cat, the option of trial therapy with Tapazole should be considered so that the effect of treatment on renal functions can be evaluated.

A trial separation is an ideal time to start marriage counselling or couple therapy if you have not done so already.

On the heels of a trial last week involving a longstanding campaign of parental alienation, in which my client was seeking reunification therapy so that his child would be treated, and counseled, to learn to want to have a relationship with her targeted father again.

More trials are needed on meditation therapies for ADHD so that conclusions can be drawn regarding its effectiveness.