Sentences with phrase «thereby interfering»

First, the exemptions subject identically - placed offenders to different periods of imprisonment (depending on whether they are able to obtain bail) for reasons that are not relevant to the determination of a proportionate sentence, thereby interfering with the principle of proportionality in the sentencing process, which is a principle of fundamental justice.

CanLII remains impressive despite their challenges of dealing with the «technical» problems caused when provinces publish their legislation in PDF (thereby interfering with their ability to make «point - in - time» legislation work).

There are some exceptions to this rule — for example, where the passenger grabs the steering wheel thereby interfering with the driver's operation of the vehicle.

Phillip Johnson, Ambush Marketing and Brand Protection (Oxford University Press, 2012): «Ambush marketing is any attempt to create an unauthorized or false association with an event thereby interfering with the legitimate contractual rights of the event's official marketing partners.»

(1) The TLABC submitted that the hearing fees wrongly impede access to justice, wrongly sell justice, and wrongly impede access to a superior court in violation of s. 96 of the Constitution Act, 1867 thereby interfering with judicial independence.

Consider this: Some aromas may be quite caustic or obtrusive, thereby interfering with your ability to unwind.

Goitrogens are substances that block the synthesis of thyroid hormones and interfere with iodine metabolism, thereby interfering with your thyroid function.

Having huge traps may sound like a great thing, but over-active traps also tend to fire whenever you're working the back and shoulders, thereby interfering with their optimal growth.

Most drugs exert their therapeutic effect by binding to a target protein molecule, thereby interfering with the normal function of the protein.

The hormone was found to directly repress the production of yolk protein in female worms, thereby interfering with an energy - costly step of reproduction.

Requests for virtual visitation are generally made by the non-custodial parent in situations where the custodial parents seeks to relocate or move out of the area with a child — thereby interfering with existing parental visitation rights.

The highly branched amylopectin is an excellent thickener and binder, while the linear amylose tends to gel and thereby interferes with several processes.

Mr. Groia argues in his appeal factum, among other things, that the panel below improperly «second - guessed» the trial judge's management of trial (and thereby interfered with the independence of judiciary) by choosing to discipline Mr. Groia for conduct that the trial judge himself did not censure.

Myth — Mothers «gatekeep» and thereby interfere with the development of paternal involvement in childcare.

Not exact matches

PPD may interfere with the infant's ability to «use» the cry signal as a way to engage or communicate with its depressed mother, thereby compromising social and emotional development.

This parallels findings by Beyth et al 190 suggesting that human MSCs interfere with normal APC maturation, thereby indirectly influencing T - cell activation.

This is in accordance with previous reports that decitabine and 5 - azacytidine produce a marked synergistic effect in combination with suberoylanilide hydroxamic acid and romidepsin in T - lymphoma cell lines by modulating cell cycle arrest and apoptosis.26, 27 As a mechanism of action, KMT2D mutations of B - lymphoma cells promote malignant outgrowth by perturbing methylation of H3K4 that affect the JAK - STAT, Toll - like receptor, or B - cell receptor pathway.28, 29 Here our study indicated that dual treatment with chidamide and decitabine enhanced the interaction of KMT2D with the transcription factor PU.1, thereby inactivating the H3K4me - associated signaling pathway MAPK, which is constitutively activated in T - cell lymphoma.13, 30,31 The transcription factor PU.1 is involved in the development of all hematopoietic lineages32 and regulates lymphoid cell growth and transformation.33 Aberrant PU.1 expression promotes acute myeloid leukemia and is related to the pathogenesis of multiple myeloma via the MAPK pathway.34, 35 On the other hand, PU.1 is also shown to interact with chromatin remodeler and DNA methyltransferease to control hematopoiesis and suppress leukemia.36 Our data thus suggested that the combined action of chidamide and decitabine may interfere with the differentiation and / or viability of PTCL - NOS through a PU.1 - dependent gene expression program.

When it comes to weightlifting and bodybuilding, this means that fish oil can be beneficial for burning fat and preventing muscle loss.Studies have shown that fish oils interfere with inflammation caused by intense training, thereby reducing its effect.

But fish oils interfere with inflammation, thereby reducing its effect on muscle, Mazurak said.

The depression also interferes with sleep patterns, making it difficult to fall asleep at night, thereby contributing to fatigue and lack of energy during the day.

The website employs a highly efficient process of filtering user profiles, thereby ensuring non-genuine users never interfere with your online dating experience.

At a time when friendships and social interaction are particularly important for young adolescents, the normative transition into high school often serves to disrupt friendship networks and, thereby, interferes with students» success in high school (Barone et al., 1991).

Advantage Multi works by interfering with nerve transmission in intestinal worms and heartworms, thereby causing paralysis and death.

The large area of warm water exposed thereby warms the air, warm air rises, interferes with trades, mixes with global circulation, and raises its temperature by half a degree.

I am sure too that the defendant must have intended thereby to interfere with the administration of justice.

We posited that youth externalizing problems [Child Behavior Checklist Externalizing Subscale (CBCL) externalizing problem scores] would contribute to patterns of conflict with caregivers, subsequently interfering with adherence processes, thereby decreasing glycemic control (increased HbA1c).