Sentences with phrase «thereby predisposing individuals»
It is hypothesized that chronic ingestion of a high - carbohydrate diet promotes obesity and increases the demand on β - cells for insulin secretion, thereby predisposing individuals to hyperinsulinemia, apoptosis, β - cell failure, and development of type 2 diabetes (21).
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Genetic factors can contribute to the degree of longevity in at least two important ways: An individual may inherit certain genetic variations that predispose him or her to disease that decreases longevity; other gene variants may confer disease resistance, thereby increasing it.