This feature decreases the bubble generation
threshold fluence below the threshold level for mono - NP clusters.
The PNB generation
threshold fluence of the pump laser pulse describes both the efficacy of the photothermal conversion by NPs and the hydrodynamic conditions of PNB generation.
Not exact matches
The observed transient behavior displays a notable «structural isosbestic» point and a
threshold effect for the dependence of c - axis expansion (Δc) on
fluence (F), with Δc / F = 0.02 angstrom / (millijoule per square centimeter).
The described system will use the following algorithms: (1) single pulse guided treatment: the pulse
fluence will be automatically maintained to provide the PNB lifetime (size) above the cell ablation
threshold.
Both
fluence levels were chosen to be significantly below the PNB generation
thresholds for single NPs (46 mJ / cm2 @ 532 nm for NSP and 32 mJ / cm2 @ 787 nm for NRs) and slightly below the PNB generation
thresholds for the mono - NP clusters of NSPs (16 mJ / cm2 @ 532 nm) and NRs (20 mJ / cm2 @ 787 nm), in order to compare the standard and rainbow mechanisms of PNB generation.
This feature also reduces the
fluence of each laser pulse below the
threshold for a nanobubble generated through a «single pulse - mono - NP» mechanism.
C: the green line shows the attenuation of optical
fluence in scattering tissue relative to the PNB
thresholds for normal and prostate cancer (PC) cells, the difference between these
thresholds determines an effective radius of PNB - based selective ablation of prostate cancer cells.
The generation of a vapor bubble around a plasmonic NP (Figure 1A) requires a specific
threshold of the
fluence of the laser pulse.