Sentences with phrase «through cytokine receptors»

The Janus tyrosine kinases (Jaks) play a central role in signaling through cytokine receptors.

Not exact matches

Current thinking regarding type III hypersensitivity is that immune cells within tissues sense the presence of these immune complexes (ICs) through specific receptor molecules and release inflammatory factors called cytokines that activate the endothelial cells lining adjacent blood vessels to promote the recruitment of neutrophils.

T cells exert their actions in two ways, either through direct cell - cell contact which involves transmembrane proteins present on both the T cell and interacting cell, or by the secretion of soluble proteins termed cytokines which have receptors on many lymphoid and some non-lymphoid cell types.

Upd2, a type - I cytokine, activates the JAK / STAT pathway through its receptor Domeless (Dome)[17][18].

Proinflammatory cytokines enhance estrogen - dependent expression of the multidrug transporter gene ABCG2 through estrogen receptor and NF -LCB- kappa -RCB- B cooperativity at adjacent response elements.

In the opposite situation, when a healthy immune system reacts to environmental factors through cytokine production, PRPs send signals via specific cell receptor sites to decrease the production of cytokines in order to balance the immune system.

Vitamin D receptors are ubiquitously expressed in T and B lymphocytes, natural killer cells, and monocytes (49, 50), and through the down - regulation of cytokines and other proinflammatory factors, vitamin D exerts profound antiinflammatory and antiproliferative actions, which would affect the turnover rate of leukocytes (1).

Citing again from the study previously mentioned titled Differential Effects of Cream, Glucose, and Orange Juice on Inflammation, Endotoxin, and the Expression of Toll - Like Receptor - 4 and Suppressor of Cytokine Signaling - 3 «Thus, saturated fats may have a more profound role in the pathogenesis of postprandial inflammation, as they may also perpetuate inflammation through the increases in LPS and TLR - 4.»