A
double -
blind flight simulation
study assessing motor performance in licensed pilots «flying»
through pre-specified (and practiced) holding patterns showed that smoking marijuana significantly increased major and minor errors, and led to larger average deviations from the assigned flight sequence, compared to those who smoked placebo cigarettes.
A paper reporting a «rigorous
double blind»
study — the VIGOR trial — was submitted to NEJM in 1998, got
through peer review at one of the most up - tight journals in the world of medicine, and — by way of cherry - picking the data submitted (selecting out some
study subjects whose adverse events histories which, if considered, would've significantly affected the safety profile for rofecoxib and revealed something that Merck really didn't want us prescribers to learn about their «blockbuster» product — was published to be touted by Merck's marketing weevils as solid proofs of Vioxx's tolerability, efficacy, and safety.