Sentences with phrase «through estrogen receptor»

Proinflammatory cytokines enhance estrogen - dependent expression of the multidrug transporter gene ABCG2 through estrogen receptor and NF -LCB- kappa -RCB- B cooperativity at adjacent response elements.

They also observed that the estrogens initiated their antiviral effects through estrogen receptor beta.

Not exact matches

The Penn scientists also utilized synthetic derivatives of estrogen and progesterone that do not bind ER / PR (but still bind the nonclassical receptors) to boost skin pigment through GPER, or decrease it through PAQR7.

On the other hand, we suspect that PCBs could provoke cancer through several mechanisms, which include the interaction with estrogen and androgen hormone receptors, the production of free radicals, or with DNA.

«The increased reward response to alcohol we see when estrogen levels are high is mediated through receptors for estrogen in the VTA,» said Mark Brodie, professor of physiology and biophysics in the UIC College of Medicine and a co-author on the paper.

BPA is believed to exert its biological effects largely through loose occupancy of the estrogen receptor, and there are reports of both estrogen agonist [7] and androgen antagonist [8] activity.

The androgen derivative 5alpha - androstane - 3beta, 17 beta - diol inhibits prostate cancer cell migration through activation of the estrogen receptor beta subtype..

Estriol (E3): Derived from estrone through the intermediate (bone - building but potentially oncogenic) 16α - OH estrone, estriol is the weakest estrogen with 20 - 30 % less affinity for estrogen receptors.

Estriol (E3): Derived from estrone through the intermediate (bone - building but potentially oncogenic) 16α - OH estrone, estriol has 20 - 30 % less affinity for estrogen receptors and is the weakest estrogen, with anti-proliferative effects in estrogen sensitive tissues (e.g., breast and endometrium).

The hypothalamus and pituitary glands have estrogen receptors liberally positioned through them.

What happens is, you eat the soy, (and I'm really simplifying) but your body mistakes these isoflavones for natural estrogen, and so as it flows through you, in your blood, it binds, or latches to your bodies estrogen receptors.

Moreover, they have shown that, through differential patterns of DNA methylation of the promoter region and thereby differential expression of the estrogen receptor alpha gene in the medial preoptic area (MPOA) of the brain, this individual variation of early experience influences adult reproductive behaviour, suggesting a mechanism for intergenerational transmission of the pattern of maternal care [137, 138].