Sentences with phrase «through leaky blood vessels»
«Importantly, this analysis helped us identify the protein fibrinogen as the key culprit in MS, by demonstrating how its entry into the brain through leaky blood vessels impacted the health of individual nerve cells.»
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«Because the particles are so small, if they happen to reach the tumor site they have a chance of penetrating through the blood vessel wall because the vasculature of tumors is usually leaky.»
«We found that the well - known Notch protein is responsible for keeping blood vessels from becoming leaky, and does so through a secondary signaling pathway that operates in a completely different manner than its known transcription - based pathway,» says Chris Chen, M.D., Ph.D., Associate Faculty member of the Wyss Institute and Professor of Biomedical Engineering at Boston University, who is the corresponding author of the paper.
Barenholz's nanoparticles generally stayed in the bloodstream and avoided the heart and other organs, but when they reached the leaky blood vessels in the tumor, they slipped through those holes.