Sentences with phrase «throughput gene targeting»

High - throughput gene targeting and phenotyping in zebrafish using CRISPR / Cas9.

The zebrafish facility at SciLifeLab has participated in the development of a high - throughput gene targeting method in zebrafish, presented in the July issue of Genome Research.

Our current LIMS systems is LIMS2, which is a successor to the HTGT (High - Throughput Gene Targeting) informatics system, which supports only the tracking of mouse clones and is now a legacy system.

Not exact matches

Choudhury used high - throughput sequencing technology to find the targets of DAZAP1 and decipher whether DAZAP1 would bind to the exons and introns of genes.

Immune function and pathology dissected by high - throughput analysis of mice with targeted gene disruptions — an investigation by the Infection and Immunity Immunophenotyping (3i) consortium.

The Mouse Molecular Technologies team provide high - throughput genotyping and characterisation of mutant mouse strains created either by targeted embryonic stem cells (ESC) or CRISPR / Cas9 gene editing in single - cell zygotes.

We are also establishing novel functional strategies, based on targeted and high throughput reporter assays, to assess the relevance of the spatial environment on gene regulation.

Drug discovery for genetic diseases: Screening technologies are applied to identify chemical compounds able to inhibit REST function, a major target gene in Huntington's disease, and will serve as a paradigm for high - throughput screening approaches applied to neurological disorders.

Instead, the researchers developed a high - throughput selection assay, CREATE (Cre REcombinase - based AAV Targeted Evolution), that allowed them to test millions of viruses in vivo simultaneously and to identify those that were best at entering the brain and delivering genes to a specific class of brain cells known as astrocytes.