Sentences with phrase «thymidine kinase»
Thymidine kinase is an enzyme found in cells that helps to convert thymidine (a molecule) into a form that is more easily used by the cell for various processes, such as making DNA. Full definition
Proteins containing only half of the coding information of early region 1b of adenovirus are functional in human cells transformed with the herpes simplex virus type 1 thymidine kinase gene and adenovirus type 2 DNA
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The AroCell TK 210 ELISA kit for thymidine kinase 1 (TK1) can aid in obtaining this valuable information from a simple serum sample.
I had also shown that when I fused it to the herpesvirus thymidine kinase (TK) gene, I could get heat - inducible TK transcripts in mammalian cells.
However, some 80 percent of solid tumors churn out extra thymidine kinase, which is thought to prevent cancer cell death.
This entailed injecting adenovirus vectors carrying herpes simplex 1 thymidine kinase into the tumor, followed by an antiviral, to elicit tumor cell death.
A Hex cDNA with a recognition sequence for bacterial BirA ligase was linked via an artificial IRES consisting of a tandem array of repeated Gtx sequences to the gene encoding Venus followed by a cytomegalovirus driven hygromycin - thymidine kinase dual selection cassette flanked by loxP sites.
Serum thymidine kinase activity in canine splenic hemangiosarcoma.
The virus can not infect noncancerous cells, Kirn explained, because researchers deleted its thymidine kinase gene, which it needs to replicate in the body.
When they found a good candidate that could deliver genes to rat brain cancer cells, they filled the nanoparticles with DNA encoding an enzyme, herpes simplex virus type 1 thymidine kinase (HSVtk), which turns a compound with little effect into a potent therapy that kills brain cancer cells.
Transforming genes coding for selectable functions, such as adenine phosphoribosyltransferase or thymidine kinase, have now been isolated by utilizing transformation in concert with molecular cloning.
It is used by veterinarians to measure two compounds in the dog's blood: the thymidine kinase (or TK) level, which indicates unusually rapid cell division; and levels of C - reactive protein (CRP), which indicates when inflammation is present.