Sentences with phrase «time points in the development»

PhD student Carles Recasens, who will defend his thesis with the results of this study in January, has discovered that «JAK / STAT appears at key time points in the development of the appendage and that it collaborates with Wingless / Wnt, Dpp / BMP and Hedgehog in wing specification and growth.»

The team is also working on a method to improve the introduction of the editing reagents — at later time points in development, for example — to refine their control of mutation rates.

Not exact matches

And I do think, John, you point to a factor here, which is we talk about and we've been talking about for a year, for example, the direction we want to go in but the development times — the development cycles are fairly extended because we have to develop dishes.

Those who knew Bonhoeffer found that the development of the spiritual life as he outlined it was not exciting to begin with, but as time passed they reassessed their views and came to regard their six - month stay in the Finkenwalde experiment as a high point of their lives.

The genius of Britain, discovered both in the internal relations of the home country and in the various parts of its actual Empire, is a curiously flexible method for the changing of the status quo — a method which prevented crises from reaching the desperation point, ensured the gradual development of liberty, and provided a model of the kind of change which is just in time to anticipate the resort to violence.

The books andwebsites on pregnancy cheerfully describe the development of «the baby», my midwife talks about listening to the baby's heartbeat and at the 12 - week scan, the time at which the majority of abortions are carried out, I lay in a darkened room and watched as my baby's head and spine and tiny hands were pointed out on a screen.

Although we would rather talk of the coherent unity of the causal complex, because, even when the development of a complex entity can be traced through contributary causes, the interlocking patterning of those causes through time and space and the higher meaningful unit of organisation which they produce still reveals order and purpose in the system which points to Transcendent Mind as First and Final creative cause.

The revolutionary social, economic, and intellectual developments in post-Civil War America stimulated within Protestantism attempts to develop a new prophetic ministry which would exercise critical judgment on the injustices which accompanied the radical changes of the period and would point the way to a new application of the gospel to the social needs of the time.

But in this way a divine preference that a certain development occur might influence the course of the universe in specific ways at specific points in space and time.

«By that point, I had worked in product development in small, medium and multi-national food companies, so I had enough under my belt to be solely responsible for the R & D department, then only myself at the time.

There comes a point in the tenure of every head coach at which he must transition from selling fresh ideas, new hope and abundant playing time to selling winning and a history of development.

All necessary body functions are working perfectly, time spent in the uterus at this point is all about lung development and weight gain.

By this time, baby's development is at a point that they are more interesting in what is going on around them rather than being solely dependent on you.

Quiz Ref IDOur conclusions are limited by our study population, which was selected from a single cohort from the United States and sampled at a single time point; thus, our findings may not be entirely generalizable to populations elsewhere or to different points in infant development.

At the same time, gambling opponents pointed to the wording of the casino amendment that highlighted the potential benefits of gambling, including an increase in economic development and school aid as a sign the administration was trying to sway voters with non-neutral language (an effort to halt the amendment as it appears on the ballot was thwarted by a state judge this month).

Some landlords in New Paltz are having a hard time swallowing Park Point because the developer has stated an intention to seek tax abatement from the Ulster County Industrial Development Agency.

The LPS was given at a time point that approximates the stage of brain development in humans right at the time of birth, thus mimicking the development of a bacterial infection during delivery.

«We have reached an important turning point in the development of the SuperKEKB, an accelerator that will have forty times the luminosity of the most powerful collider ever built.

«Examining developmental changes in the brain over a critical period of reading appears to be a unique sensitive measure of variation and may add insight to our understanding of reading development in ways that brain data from one time point, and behavioral and environmental measures, can not,» said Chelsea Myers, BS, lead author and lab manager in UCSF's Laboratory for Educational NeuroScience.

«It's very mysterious at this point in time, we don't really know what's contemplated there,» Fulton says, «If you piece together the different things that have been said by the president - elect about fossil fuels, and encouraging fossil fuel development, you'd expect this would have something to do with that.»

In explaining the increasingly important role that the science community will play in determining the progress of international efforts toward sustainable development and climate stability, Lovász pointed out that the majestically ornate Hungarian Academy of Sciences neo-Renaissance palace in which the WSF was held was built entirely with public donations 150 years ago, «which illustrates the trust that Hungarian society from the nobility to poor farmworkers had in science at that time.&raquIn explaining the increasingly important role that the science community will play in determining the progress of international efforts toward sustainable development and climate stability, Lovász pointed out that the majestically ornate Hungarian Academy of Sciences neo-Renaissance palace in which the WSF was held was built entirely with public donations 150 years ago, «which illustrates the trust that Hungarian society from the nobility to poor farmworkers had in science at that time.&raquin determining the progress of international efforts toward sustainable development and climate stability, Lovász pointed out that the majestically ornate Hungarian Academy of Sciences neo-Renaissance palace in which the WSF was held was built entirely with public donations 150 years ago, «which illustrates the trust that Hungarian society from the nobility to poor farmworkers had in science at that time.&raquin which the WSF was held was built entirely with public donations 150 years ago, «which illustrates the trust that Hungarian society from the nobility to poor farmworkers had in science at that time.&raquin science at that time.»

This link was only evident in blood samples taken at a time point reflecting exposure during early pregnancy when the fetal nervous system undergoes rapid development, not at birth.

It also points to new mechanisms at work in the brain development of individuals and in species like humans over evolutionary time.

To achieve this that fate of these cells must be precisely regulated, such that the right number and type of cells is created at a given time and point in development.

But the term may be applied more casually to point to things (such as an individual's brain development) that change in form or function, over time, in response to cues (such as developmental hormones).

Eight HARs showed differences in their enhancer activity when the human mutations were present.4 These differences modify how genes were expressed in the developing limb (HAR2, 2xHAR114), eye (HAR25), and central nervous system (2xHAR142, 2xHAR238, 2xHAR164, 2xHAR170, ANC516 / HARE5).4, 10 Because relatively few time points have been examined, it is likely that an even higher percentage of the tested HARs are active enhancers at some point during embryonic development or in adult tissues, possibly with human - chimp differences.

As for the HARs that weren't active in brain cells during the study, the scientists think they could influence gene expression at other time points during development, such as when the neuron is fully matured rather than while it's developing.

«Longitudinal research [like this] offers insight into what factors may be the best or strongest predictors of children's development, over and above information that can be gathered at only one time point,» she said in a university news release.

Here we demonstrate that bisphenol A exposure during a time point analogous to the second trimester in humans has real and measurable effects on brain development and behavior.

It is Dr. Fasano's team discovery that «zonulin,» is the molecule which regulates intestinal permeability (also known as «leaky gut») and their totally ground - breaking research that linked an overproduction of zonulin (gluten is a clear known trigger for such in celiacs) to the development of a series of autoimmune diseases, including Type 1 diabetes, celiac disease and multiple sclerosis (at least in animals at this point in time).

I had a hard time staying engaged because with every single mission you have to read the description in order to see character development and to see the point of what you are doing.

• Legend of Zelda • Super Smash Bros. • «X» • Bayonetta • Mario Kart (if that even counts much as a «heavy - hitter» anymore — despite its popularity, the series is a given, by this point, and likely didn't cost very much in terms of development budget and time unlike the other aforementioned)

For another, it's not in the nature of movies to reflect the times so quickly: it took 15 years of development and rewriting as well as the invention of new technologies to make Benjamin Button possible, and although Milk came together with remarkable speed and focus under its producers Bruce Cohen and Dan Jinks, the idea of making a biopic about Harvey Milk, who was killed in 1978, has been around for so long that at one point, Dustin Hoffman, now 71, was touted to play the role that eventually went to Sean Penn (who is 48).

Also not really sure about your point of trailer in 2010 — there's no conclusive evidence that significant development had been made at that time...?

And, the fact is, that's how most people decide to get married — when they reach a certain point in their lives, or their physical and psychological development, that they decide it's time to get married.

At this point in the game, and The Hateful Eight marks Tarantino's eighth feature film, audiences know what to expect from QT; fetishized wish - fulfillment violence, artfully staged, of course, pitch - dark comic relief, gratuitous and indiscriminate n - bombs dropped peremptorily, intricate plot developments that reveal themselves unexpectedly, linear time an option, not a maxim, and a jeering mise - en - scène certain to be dissected and redesigned.

As we learned yesterday, there was one point in time, very early in the development process, that A Quiet Place was...

It's been in development since 2009, a long time even for animation, and though LeFauve has sole screenplay credit, the fact that she shares story credit with four other writers — Sohn, Erik Benson, Kelsey Mann and Bob Peterson (who also has an original concept and development credit) points up how many cooks were involved in this tasty broth.

Long languishing in a peculiarly Middle Eastern form of «development hell», The Time That Remains adopts a deadpan vignette - heavy form loaded with the pointed absurdism that will be familiar to anyone who's seen the director's earlier work.

At one point during the film's development, the question was raised whether it was worth investing such a significant amount of money and screen time in what is essentially a giant prank on the audience.

Given the film's reportedly chaotic development, there's probably five times as much fascinating footage as we get in a tantalizing selection of «Deleted Scenes» (12:22, SD), but we're given trims that compliment the finished product: CIA Director Ezra Kramer (Scott Glenn) testifying before Congress and firing Landy, a slaying on the streets of Spain, Ross getting a point in the right direction, Bourne attempting to squeeze information from a contact, extra footage from the Waterloo Station sequence, two strategic pow - wows between Landy and Vosen, and Bourne seeing off Parsons.

Stockwell knows how to film in the water, except he relies too much on the Blue Crush formula to get from point A to B, filling up precious screen time with undulating bodies and hard - hitting music in place of where much - needed character development should be.

In it, they tell terrible tales of bank accounts being drained — «There was one point where I had emergency gallbladder surgery that put me in the hole $ 50k due to the fact that I couldn't afford health insurance,» McMillen writes — to an endless, vicious cycle of bugs, testing and development crunch hell — «We were basically developing features during bug checking, which meant every single time I turned on the computer and checked the bug database, the work I did the night before was pretty much rendered irrelevanIn it, they tell terrible tales of bank accounts being drained — «There was one point where I had emergency gallbladder surgery that put me in the hole $ 50k due to the fact that I couldn't afford health insurance,» McMillen writes — to an endless, vicious cycle of bugs, testing and development crunch hell — «We were basically developing features during bug checking, which meant every single time I turned on the computer and checked the bug database, the work I did the night before was pretty much rendered irrelevanin the hole $ 50k due to the fact that I couldn't afford health insurance,» McMillen writes — to an endless, vicious cycle of bugs, testing and development crunch hell — «We were basically developing features during bug checking, which meant every single time I turned on the computer and checked the bug database, the work I did the night before was pretty much rendered irrelevant.

Moreover, he pointed that they were glad to have this much development time from Sony as it took Guerrilla a long time to nail down the combat and make it feel as good as it does in the final version.

At any given point in time, studios are juggling multiple projects in various stages of development.

Now that many Star Wars fans have seen The Last Jedi, it's time for everyone to weigh in on what they think of Rey's development at this point in the franchise.

Recognition of the value of school leaders» autonomy in determining the best strategies at any particular point in time in a school's cycle of development 4.

Osprey Lake of the Women's Earth and Climate Action Network (WECAN) in the United States, where the battle over the Keystone XL Pipeline and the development of the Alberta Tar Sands is raging, addressed the failure of the COP to deal with the central point of ending fossil fuel extraction: «With the COP taking place in Peru, it is the first time a UNFCCC meeting was held in an Amazon country.

This is inefficient because new staff may be added at different times and current staff may be at different points in their professional development.

The key points from each strand are highlighted as follows: Early Identification and support • Early identification of need: health and development review at 2/2.5 years • Support in early years from health professionals: greater capacity from health visiting services • Accessible and high quality early years provision: DfE and DfH joint policy statement on the early years; tickell review of EYFS; free entitlement of 15 hours for disadvantaged two year olds • A new approach to statutory assessment: education, health and care plan to replace statement • A more efficient statutory assessment process: DoH to improve the provision and timeliness of health advice; to reduce time limit for current statutory assessment process to 20 weeks Giving parent's control • Supporting families through the system: a continuation of early support resources • Clearer information for parents: local authorities to set out a local offer of support; slim down requirements on schools to publish SEN information • Giving parents more control over support and funding for their child: individual budget by 2014 for all those with EHC plan • A clear choice of school: parents will have rights to express a preference for a state - funded school • Short breaks for carers and children: a continuation in investment in short breaks • Mediation to resolve disagreements: use of mediation before a parent can register an appeal with the Tribunal