Sentences with phrase «times current estimates»

When they multiplied that result times current estimates of the number of functional genes, it came to about 3,000 to 7,000.

Factor in these long - term complications and the total cost of diabetes is almost four times the current estimate.

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

Version nine, which is almost complete, cost about 35 percent less than the current version in space, and was made four times faster, he estimated.

London's current budget is nearly four times higher than initial estimates.

This will mean a longer wait for more recent arrivals than the current 20 - month average estimated time for processing claims.

This past April, the United States Energy Information Agency released an estimate that fracking has effectively increased the volume of recoverable gas in the world six times over, to the point where it could satisfy current demand for 250 years — and that isn't counting a number of countries including Russia where the necessary geological data were unavailable.

Denton was featured in the Sunday Times Rich List 2007 in position 502 with an estimated wealth of # 140m (approximately $ 290m) based on the sale of his previous companies and the current value of Gawker Media.

Jonas said that would be 4 - times larger than his estimate for Uber's current fleet.

A real - time GDP tracker from the Atlanta Fed suggests that the economy only expanded at a 1 percent annualized rate in the third quarter, well below the current consensus estimate of 2.5 percent.

Put simply, even taking account of current interest rate levels, and even assuming that stocks should be priced to deliver commensurately lower long - term returns, we currently estimate that the S&P 500 is about 2.8 times the level at which equities would provide an appropriate risk premium relative to bonds.

The four pillars are: timing of the tabling of the Main Estimates; the scope and accounting methods used in the Estimates and the Budget; changes to the current vote structure; and changes to the Reports on Plans and Priorities and the Departmental Performance Reports.

Forward - looking statements are based on estimates and assumptions made by BlackBerry in light of its experience and its perception of historical trends, current conditions and expected future developments, as well as other factors that BlackBerry believes are appropriate in the circumstances, including but not limited to the launch timing and success of products based on the BlackBerry 10 platform, general economic conditions, product pricing levels and competitive intensity, supply constraints, BlackBerry's expectations regarding its business, strategy, opportunities and prospects, including its ability to implement meaningful changes to address its business challenges, and BlackBerry's expectations regarding the cash flow generation of its business.

Supplementary Estimates include spending requirements included in the Budget which were not sufficiently developed in time for inclusion in the Main Estimates or have been subsequently refined to reflect current developments.

The four pillars are: timing of the tabling of the Estimates; the scope and accounting methods used in the Estimates and the Budget; changes to the current vote structure; and changes to the Reports on Plans and Priorities and the Departmental Performance Reports.

Hopefully, these connections will allow people working in corporations to feel better (current estimates show employee engagement at an all - time low in this country, with 70 % of the US workforce being disengaged), do better and create a happier workforce which is equally productive, profitable and purpose driven.

Given the current enterprise value of $ 440m, Cardno is trading on a multiple of just over six times this estimate.

The report, entitled Homelessness Projections: Core Homelessness In Great Britain, stated: «If current policies continue unchanged, the most acute forms of homelessness are likely to keep rising, with overall numbers estimated to rise by more than a quarter in the coming decade and two and a half times by 2041.»

Further, current estimates are that, 250 million years time, the stars of the Pleiades cluster will have in fact dispersed: they are not «bound» together, as implied in the verse.»

They estimate the current extinction rate is 100 to 1,000 times the average rate...

This could be occasion to paint a bleak picture: The current rate of global diversity loss is estimated to be a 1000 times higher than the extinction that would occur naturally.

In one study, a large reduction in blood pressure associated with having been breastfed for at least 3 months (Web table 1) was reported to have been somewhat attenuated after controlling for current weight, age, birth weight, time of birth, birth order, mother's age, and history of high antenatal maternal blood pressure (14), but quantitative estimates suitable for inclusion in the meta - analyses were not available.

The current proposition seems to be that the Hinkley plant will now cost double its original estimate, some # 14bn, and could require underwriting at a higher cost than most renewables, and over almost three times the period envisaged.

The Carbon Trust has estimated that wave power could eventually meet between 15 % and 20 % of our current power needs and that, given time, it might produce enough electricity to power 11 million homes.

Gelinas says if the state wants to pay for the project, estimated at $ 4 billion dollars, it will have to raise tolls by three times as high as the current rate of $ 5.00.

«The timing of payments and the level of financial sector bonuses will influence whether current estimates are met in the final quarter of the fiscal year.»

Bob Wisnieff, the principal investigator of the IBM study, says their current simulation runs about «a billion times slower» than the theoretical estimates for an actual 56 - qubit quantum computer.

The cost to treat and recycle water used at power plants is estimated to be 1.5 to 2 times the cost of freshwater, often because of the high price of current silica removal methods.

But the size of the observed bloom could mean that current estimates of the rates of so - called primary production — the production of organic molecules that results from phytoplankton consuming nutrients and photosynthesizing — on the Arctic continental shelf may be as much as 10 times too low, the team reports online today in Science.

The current rate of extinctions is, by some estimates, 10,000 times the average in the fossil record.

The new study found that the species then rose from less than 90,000 animals in 1975 to an estimated 281,450 in 2008, which was roughly the carrying capacity for sea lions in the California Current Ecosystem at that time.

Thinking that I might have a hot story to write about that would reveal something deeply wrong with current cosmological models, I first queried California Institute of Technology cosmologist Kip S. Thorne, who assured me that the discrepancy was merely a problem in the current estimates of the age of the universe and that it would resolve itself in time with more data and better dating techniques.

According to some estimates, the available energy in the jet streams is about 100 times the current global energy demand.

The current version of the software doesn't estimate the breathing rate in real time, but the researchers are working to incorporate this capability and to test their algorithms in more real - life situations.

New climate models — made by using estimated radiation levels from that time, along with data from the Magellan spacecraft about Venus's current surface — suggest that Venus would have been only 11 °C (52 °F).

This suggested there were plausibly 2.2 million TB cases, possibly more, treated in the private sector in 2014 — two to three times higher than current estimates.

Brusaw estimates that the cost of each panel would be around $ 10,000, which — based on figures from the Idaho Transportation Department — he estimates to be roughly four times the current cost of laying asphalt.

The aircraft and road traffic noise exposure levels estimated for their postcodes at that time — less than 50 decibels to more than 60 dB — were used for the current study in 2013.

One tentative estimate put warming two or even three times higher than current middle - range forecasts of 3 to 4 °C based on a doubling of greenhouse gases in the atmosphere, which is likely by late this century.

They estimated that participants with elevated CAC scores (> 100) were 2 − 4 times more likely to benefit from aspirin therapy than to be harmed, even if they did not qualify for aspirin use according to current AHA guidelines.

The best estimate for the current toll in Africa, 21,000 deaths, comes from a 2015 paper by Hampson and colleagues; it's 100 times higher than official figures.

Importance Estimates of the rate of revision septorhinoplasty and the risk factors associated with revision are unknown because the current published literature is limited to small, retrospective, single - surgeon studies with limited follow - up time.

Recent innovations in multivariate models allow researchers to simultaneously estimate multiple determinants of current ability as well as changes in ability over time (Jacobucci et al., 2018).

Current polar orbiting satellites can only provide a single snapshot of carbon dioxide uptake and water release each day, at the same time of day, so scientists have to estimate how that one - time snapshot translates over the course of the entire day.

Estimates of current and ancestral population sizes (Ne1 = 1,600,000; Ne2 = 780,000; Nancestral = 470,000), divergence time (1,800,000 years and assuming a generation time of 1 year), and gene flow (2Nm1autosomal = 1.69; 2Nm2autosomal = 0.83; 2Nm1X - chromosome = 0.38; 2Nm2X - chromosome = 0.26) were obtained from previous studies and inferred using an Isolation - with - Migration model [21], [26].

They estimate its current size to be about one - tenth of a light - year, or 170 times the distance between the sun and Pluto.

[ix] Because loan amounts naturally grow over time with interest, estimates here are expressed in current dollars to avoid confusion.

With direct - injection, a variable - displacement oil pump and variable cam timing, it makes an estimated 150 horsepower and 177 lb - ft of torque, up 12 hp and 29 lb - ft from the current car's 1.4 - liter turbo, and it's mated to an updated six - speed automatic transmission.

An updated dashboard computer records important stats like average trip speed, trip time, estimated miles to empty, current radio station, current fuel consumption, and more.

It's also possible to share destination, current location and estimated time of arrival (ETA) with others via email or text message1.