These substances do not degrade and are susceptible to infection; they remain in the tooth until they need to be replaced, which can happen multiple
times over a patient's life.
Not exact matches
Some of the challenges for this are government requirements tying prices to the lowest available, and the fact that
patients switch health insurance providers numerous
times over the course of their lives — an average of every three years, according to Spark.
Cancer
patients need
time and drugs that,
over time, are effective.
«If you're
patient and are reinvesting the income,
over time you are going to be better off with the higher income payout.»
One remarkable aspect of these treatments is they're essentially one - and - done —
patients don't have to keep receiving infusions
over time.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror
patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured
patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and
patients may not see advantages of these products
over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from
time to
time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
PROMs are questionnaires that
patients complete that assess how health services and interventions have,
over time, affected their quality of life, daily functioning, symptom severity, and other dimensions of health, which only
patients can know.
Finally, now is the perfect
time to be
patient in the market, especially considering the string of nice winning trades our Wagner Daily stock newsletter has had on the short side of the market
over the past week.
We are
patient investors who believe that,
over time, the price of a stock will rise to reflect the value of the underlying company.
Steady economic growth translated into dividends compounded
over time can result in huge gains for
patient stock market investors.
Given
patient mix, we could be conservative in our assumption that the blended avg price per
patient over time is ~ $ 200K as this is below Myozyme ($ 600K) pricing.
The drug overdose epidemic has become one of the most concerning public health issues of recent
time, and in an effort to stem the tide, moreg and more
patients and doctors are turning to pot
over pills.
If somebody has had a terrible
time in life and they have gone through one tragedy after another and you tell them that God loves them, they might just laugh at you... Many
times we have to be willing to show people the love of God, and that can be anything from being
patient over a long period of
time to providing for a physical need that they have that may cost [us] some money.
The whole truth is not given to us in advance on authority, but must be teased out
over time through
patient searching.
The December 1986 Hastings Center Report indicates that «many AIDS
patients report 1,000 sexual partners
over a single life
time.»
After the batter fluffs up and looks firm / mostly cooked, flip it
over to cook the other side (be
patient, this takes a little
time!).
Be
patient with these; they need to stay
over indirect heat the whole
time to minimize flare - ups.
Taylor's running style makes it hard to believe he still has so much
time left — he's really
patient, but he's thick enough to run defenders
over in the open field.
The Pirates trailed at the half, but the Bluejays» cast of precise and
patient perimeter players — call»em the Mutuals of Omaha — then came a cropper, turning the ball
over so many
times that Creighton coach Tony Barone, a former Chicago Cub batboy, must have been tempted to reach for the pine - tar rag.
How cld we be that negative while we have bn
patient for
over a decade??? if we do not win anything this season then pple will know my true negativity.it's
time to stand up and be on the right side of the club's history!!!
We were turning the ball
over far too much in our often
patient build - up — which left us vulnerable to a quick transition in which we paid the price for too many
times.
«Weight also appeared to be a factor associated with the rate of meniscal tears found at the
time of surgery,» comments senior author, Philip Wilson, MD. «Our data demonstrates
patient weight
over 143 lbs (65 kg) to be associated with an increased rate of medial and lateral meniscal tears at the
time of surgery.
But Conrad Murrary is facing several years of jail
time for letting one
patient die a preventable death, while Lisa Barrett is nominated as a «hero» having presided
over FIVE preventable deaths.
A long - term relationship between a
patient and provider or provider group ensures that a complete medical history and other health information are easily available, and that care is consistent and coordinated
over time.
In the country's 250 birth centers, midwives tend to take far more
time with
patients than busy doctors do and the emphasis is on the whole woman — everything from consultations on what a woman should be eating during pregnancy to conversations about anxiety
over delivery.
The more you know before you put the gown on and become a «
patient», prepare yourself so you don't have too many regrets (which can haunt you
over time).
The
time I spend with my
patients, the ways I get to know them, the blood, sweat, tears, and not to mention mountains of debt that I've accrued
over the years just to do this calling, this horrible calling that overworks me, underpays me, and leaves me with more stress and a shorter lifespan is all turned into some nebulous evil doctor woo woo that completely disregards me (and not to mention my
patients who you seem to view as bleating sheep) as a professional and as a human being.
They don't realize that you, the
patient, are being dragged through those emotions
over and
over again as they feel them for the first
time.
«If reproduced
over longer
time periods and across the UK, as a whole, the additional numbers of
patients presenting to [emergency care], with alcohol related problems could be very substantial.»
In the beginning, teaching was my passion, but I didn't just want to be a teacher; I wanted to be a teacher with a difference, I wanted to teach how to save lives, so I decided to study medicine, that way I get to be a doctor and a teacher at the same
time, which I still want to do, but
over the years I have come to fall in love with medicine, I want that instant gratification of treating a
patient and seeing them get better right in front of you, I mean that is the definition of joy for me.
Ed Miliband claims David Cameron fails to answer directly his questions
over waiting
times for cancer
patients.
This month's referral to treatment
times in Wales have shown a large increase in the number of
patients waiting
over 9 months to start a course of treatment.
Cuomo had raised expectations
over the weekend, when the New York
Times reported that the governor would embrace medicinal marijuana in his speech, with a new plan that revived a dormant 1980 statute allowing designated hospitals to prescribe the drug to approved
patients.
Dr Haruna, however, said Governor Yahaya Bello, has expressed deep concern
over the incident and has directed that all the
patients be treated at no cost and also charged the State Ministry of Health to conclude investigation within the shortest possible
time and prevent further spread of the disease.
Since then they have employed the system more than 45
times on
patients ranging in age from under 18 months to
over 60 years.
Rather than replace existing cochlear implants, it's likely that the two technologies will be combined, to give
patients a system with greater flexibility that can adapt to their needs
over time.
Over time, we have fostered special relationships with
patients and family members, and many have become our closest friends.
Future research should focus on how relationships between religious or spiritual involvement and health change
over time, and whether support services designed to enhance particular aspects of religion and spirituality in interested
patients might help improve their well - being.
Development of the drug was stopped after some
patients experienced a reduction in cholesterol lowering
over time.
Researchers said further studies are also planned that use other methods to analyze the relationship between volume and outcomes, follow
patients after discharge from the hospital, and assess how
patient outcomes are affected as hospitals gain more experience with TAVR and the technology is refined
over time.
Once opioids and sedatives have been prescribed, changing the dose must be done gradually and carefully, especially when a
patient has been accustomed to higher doses
over a longer period of
time.
These genetic mutations can fluctuate
over time, and some
patients can harbor more than one mutation,» said Zofia Piotrowska, MD, lead author of the study and a thoracic oncologist at the Massachusetts General Hospital Cancer Center in Boston.
I chose cardiology, and specifically heart failure, because I wanted to work in a subspecialty where I could care for a group of
patients over time, in my case
patients with chronic heart disease.
While we observed that biopsies were generally safe and feasible, noninvasive testing methods, such as liquid biopsies that analyze tumor DNA circulating in the
patient's blood, may provide another method to more easily characterize resistance
over time.»
«Although radiosurgery has been shown to be an effective post-surgical treatment for metastatic brain tumors, previous studies did not compare
patient outcomes from a single hospital
over the same period of
time,» said N. Scott Litofsky, M.D., chief of the Division of Neurological Surgery at the MU School of Medicine and senior author of the study.
«We'll certainly be looking at whether
patients who manage their pain with cannabis can reduce their opioid doses
over time or even wean themselves off opioids entirely,» he says.
The mean survival
time for this disease, which predominantly occurs in the elderly, is less than a year for
patients over 65 years.
Future trials might show improved results from testing the drug candidate in even younger
patients or
over much longer periods of
time, the scientists say.
Over a median follow - up of nearly eight years,
patients who were current smokers had a 40 % increased risk of cancer relapse, as well as more than 2 -
times increased risks of cancer spread and cancer - related death, compared with
patients who were never smokers.
«This study demonstrates the value of using the SEER database to analyze factors associated with surgery as a treatment for localized pancreatic cancer in a large number of
patients over a prolonged period of
time,» says Dr. Kim, who is also Chief Medical Officer of UH Seidman Cancer Center and the Charles Hubay Professor at Case Western Reserve School of Medicine.