The trick to getting the size down, says project leader John Kitching of NIST, was combining numerous microfabrication tricks, including a novel method for trapping cesium atoms in
tiny glass cells, a technique developed by his collaborators, Svenja Knappe and Li - Anne Liew, also at NIST.
Not exact matches
To insert genes into a
cell, scientists often prick it with a
tiny glass pipette and inject a solution with the new DNA.
The well plates used in drug screening, for example, may contain as many as 1,536
tiny wells on a playing - card - size piece of
glass or plastic, allowing researchers to conduct that many individual experiments by dosing each
cell with a different compound.
Kodandaramaiah, Boyden and Forest set out to automate a 30 - year - old technique known as whole -
cell patch clamping, which involves bringing a
tiny hollow
glass pipette in contact with the
cell membrane of a neuron, then opening up a small pore in the membrane to record the electrical activity within the
cell.
The WSU research team fitted a mat of
tiny glass springs with specially designed biomarkers that attract the fatty droplets of proteins and RNA that tumor
cells shed into body fluids.
PNNL says, «Using inexpensive
glass beads traditionally used for reflective pavement markings at airports, the PNNL team has demonstrated 1000x magnification, which is necessary to see
tiny anthrax spores and plague
cells.