Sentences with phrase «tissue analysis of»

Their soft - tissue analysis of bones has been largely limited to the muscle scars that can be seen with the naked eye.

Not exact matches

Right now such cancers are usually confirmed by way of a biopsy — a doctor literally removes tissue and sends it to a lab for analysis, which can take days.

Biopsy to remove tissue for diagnostic analysis can damage lactation ducts or nerves depending on the technique, amount of tissue removed and location of the incision.

Blood tests of liver functions provide important clues that aid in the diagnosis, and a liver biopsy (an analysis of a small sample of liver tissue under a microscope) often provides the definitive answer.

For that, Meteyer explains, microscopic analyses of skin tissue must confirm that the pathogen «is eroding it — actually eating away the skin of the bat.»

By examining tissue from different disease stages within valve samples of the same patient, the researchers were able to avoid donor variation in their analysis.

The analysis shows that the soft tissue layer around the bones retained traces of ferrous iron, a relic left over from haemoglobin that was also trapped in the sample.

In cancer research, our goal is to be able to start with a sample of human tissue, extract many cells of interest, and perform genetic analysis upon each of them separately.

An analysis of the HPV16 genome from 5,570 human cell and tissue samples revealed that the virus actually consists of thousands of unique genomes, such that infected women living in the same region often have different HPV16 sequences and variable risks to cancer.

The researchers used stable isotope analysis, a chemical assay of a tissue biopsy that provides an integrative view of what the animal ate in previous months.

The analysis revealed belly fat tissue biopsied in the winter had a higher level of two genetic markers for beige fat, compared to the samples taken in the summertime.

In an analysis of Medicare billing data submitted by more than 2,300 United States physicians, researchers have calculated the average number of surgical slices, or cuts, made during Mohs micrographic surgery (MMS), a procedure that progressively removes thin layers of cancerous skin tissue in a way that minimizes damage to healthy skin and the risks of leaving cancerous tissue behind.

Further analysis including in tissues from more patients with other forms of epilepsy also showed that CLOCK RNA and protein were often significantly lacking in both in excitatory and inhibitory neurons in affected brain regions.

However, in recent post mortem analyses of HD patients who received transplants of non-HD tissue in an attempt to repair their brain, the researchers showed that the mHtt can be found in the graft itself.

Dr Brastianos will say: «When brain metastasis tissue is available as part of clinical care, we are suggesting sequencing and analysis of that sample.

Conventional techniques for recovering ancient human DNA typically require the destruction of bone or tooth tissue during analysis, and this has been a cause of concern for many Native and indigenous communities.

Two months after therapy, tissue analysis showed less scarring and higher levels of regenerative agents such as fibroblast growth factor — which accelerate healing — in rats treated with SIS plus stem cells compared with those treated with SIS alone.

A postmortem analysis of human brain tissue, for example, conducted by Witelson and her colleagues at the Michael G. DeGroote School of Medicine at McMaster, revealed that women's neurons were 11 percent denser than men's in the prefrontal cortex and in a region of the temporal cortex that is involved with language processing, comprehension, and memory.

Analysis of blood and tissue samples from one patient revealed that plakoglobin was expressed in CTC clusters but not single CTCs and also was expressed in some portions of both the primary tumor and metastases.

They then performed statistical analyses to identify the key drivers of organ regeneration across different types of tissues.

Additionally, analyses of patient tissue samples showed that AEG - 1 and Akt2 expression correlated with GBM progression and reduced patient survival.

The scientists hope that publication of the protocol will also lead to an exchange with and further developments by colleagues with a view to advancing metabolic analyses of archived tissues.

«New protocol enables analysis of metabolic products from fixed tissues.»

Post-hoc analysis of the efficacy of first - line gefitinib revealed there was similar progression - free survival (PFS) for those with EGFR mutation positive tissue (9.7 months [CI 8.5 - 11.0]-RRB- versus both mutation positive tissue and plasma (10.2 months [CI 8.5 - 12.5]-RRB-.

Using virus histochemical analysis, the investigators looked at the pattern of attachment of two genetically engineered emerging H7 viruses (containing the hemagglutinin (HA) of either influenza virus A / Shanghai / 1 / 13 or A / Anhui / 1 / 13) to fixed human respiratory tract tissues and compared the findings to attachment patterns seen with human influenza viruses with high transmissibility but low virulence (seasonal H3N2 and pandemic H1N1) and highly pathogenic avian influenza (HPAI) viruses with low transmissibility and high virulence (H5N1 and H7N7).

«Our method permits the analysis of minute biopsies and even tissue micro-arrays, making it particularly interesting for molecular research and diagnostics,» explains doctoral candidate Achim Buck, together with Alice Ly, the first author of the study.

The researchers compared the DNA methylation profiles of thousands of genes in breast, colon, lung, and endometrial tissues, selecting one gene, TRIM29, for further analysis.

A new mass spectrometry imaging protocol allows the analysis of metabolites like Adenosine monophosphate from FFPE tissue, shown here as background.

Since the analysis uses light beams, SHP is not limited to thin sections of biopsy specimens — in fact, one can apply the method directly in live tissue, where it allows to inspect a site of interest with the aid of fibre - optics.

The current state - of - the - art method for diagnosing cancers and determining the boundary between cancer and normal tissue during surgery, called Frozen Section Analysis, is slow and sometimes inaccurate.

«As there are no published guidelines for the use of ctDNA for EGFR mutation analysis in the absence of tumor tissue, these results may help address this current unmet need.»

To unravel the complex signaling pathway map, the scientists used their own findings from the analysis of factors regulated up or down in the interplay between tissue and stem cells, linking them with the signaling pathways described in existing literature.

Analysis of the soft tissues of fossils also suggests morphological changes among lingulid brachiopods.

The massive analysis of human, chimpanzee, and monkey tissue published Nov. 23 in the journal Science shows that the human brain is not only a larger version of the ancestral primate brain but also one filled with distinct and surprising differences.

Analysis of the surfaces of the leaves revealed that the number of plant pathogens as well as of necrotic plant tissues increased considerably when mutualistic Pseudomyrmex ferrugineus ants were absent.

Analysis of images showed that the contrast used by the research team bound almost exclusively to the fibrin - fibronectin complexes, producing a strong and prolonged image enhancement of micrometastases and tumors compared with normal tissue.

Intravital two - photon bone imaging is superior compared with conventional analyses of the shape and form of a tissue because it enables two - dimensional scanning in bone in a focal plane to observe cell shapes and the appearance of mOBs and mOCs in the body.

Tissue analysis has confirmed the diagnosis, but it turns out that even this second patient didn't have a typical case of the disease: Johann F. suffered from the less common «plaque only» variant.

The researchers are also planning to conduct further analyses of patient samples to confirm their results, and are working with Charité - based cardiologists to determine the role of adipose tissue in patients with heart failure within the clinical setting.

Analysis revealed that trans fats from both animal and vegetable sources were significantly more abundant in the fat tissues of heart attack patients than in the healthy volunteers.

Other collaborators included David C. Williams M.D., Ph.D., co-director of the Tissue and Data Acquisition and Analysis Core at VCU Massey Cancer Center, researcher in the Developmental Therapeutics program at Massey and assistant professor in the VCU Department of Pathology; and Andrea Ferreira - Gonzalez, Ph.D., professor in the VCU Department of Pathology.

To help identify genes and signaling pathways that may be influenced by zinc, Knoell and his team performed a genome - wide microarray analysis of lung tissue taken from zinc - deficient mice with sepsis.

In an analysis of postmortem human brain tissue from 137 control subjects, they also found an association between the ECR47 risk variant and reduced ADGRL3 expression in the thalamus, a key brain region for coordinating sensory processing in the brain.

PEOPLE suspected or convicted of sex offences, serious assaults or burglaries in England and Wales will have to give a sample of tissue or blood for DNA analysis from next month.

Using a very sensitive DNA analysis technique that can also be employed when only very small amounts of DNA from old tissue are available, the researchers could compare the two current cell lines with the tumor from which the cell line was established.

After ScienceInsider revealed last week that scientists were condemning its use of DNA testing and isotopic tissue analysis to decide the fate of asylum seekers, the U.K. Border Agency has apparently changed its plans.

Miniaturising the key steps in DNA analysis could allow computerised machines the size of credit cards to perform forensic tests, tissue typing for transplants and other DNA analyses in minutes, rather than the days or weeks now needed.

For the new analysis, his team spent 5 years collecting brain tissue from 59 people who had died or had such tissue removed during surgery for epilepsy at different ages, ranging from before birth to 77 years of age.

The analysis of different tissues demonstrated MOCOS expression in the brain cells and intestine of several species, and notably the C. elegans worm and mammals.

But after treatment, tissue analysis showed that only 45 per cent of the abnormal axons were still there.